Results 51 to 60 of about 33,018 (264)
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Chandra X-Ray Observatory Observations of 13 Fermi LAT Sources
The Astrophysical JournalIn the latest data release from the Fermi Gamma-ray Space Telescope (the 4th Fermi LAT 14 yr Catalog, or 4FGL), more than 50% of the Galactic sources are yet to be identified.
Blagoy Rangelov +5 more
doaj +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
The 157 Month Swift/BAT All-sky Hard X-Ray Survey
The Astrophysical JournalThe Burst Alert Telescope (BAT) on board the Neil Gehrels Swift Observatory has been serving as a survey instrument for the hard X-ray sky, and has detected thousands of X-ray sources (e.g., active galactic nuclei, X-ray binaries, etc).
Amy Y. Lien +14 more
doaj +1 more source
A multi-frequency study of the deep Pavo field [PDF]
Serbian Astronomical Journal, 2003 We test the prediction of Hamilton and Helfand (1993) that faint radio selected galaxies are a new class contributing to the diffuse X-ray background (XRB) radiation.
Filipović M.D. +11 more
doaj +1 more source
THE GALACTIC BULGE SURVEY: COMPLETION OF THE X-RAY SURVEY OBSERVATIONS
The Astrophysical Journal Supplement Series, 2014 10 pages, 5 figures, accepted for publication by ApJS.
Jonker, Peter G. +10 more
openaire +5 more sources
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
EROSITA: AGN SCIENCE, BACKGROUND DETERMINATION, AND OPTICAL FOLLOW-UP SPECTROSCOPY
Acta Polytechnica, 2013 More than 20 years after the highly impacting ROSAT all-sky survey in the soft X-ray spectral range, we are close to the next major X-ray all/sky surveys with eROSITA. eROSITA will be the primary instrument on-board the Russian “Spectrum–Roentgen–Gamma” (
Thomas Boller
doaj +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source