Results 61 to 70 of about 491,746 (343)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Analyses non destructives par tomographie à rayons X

Les Nouvelles de l’Archéologie, 2020
X-ray imaging techniques benefit from developments in physics, mathematics, and computer science, and provide analytical tools to study 3D internal structures of a wide range of objects.
Patricia Wils
doaj   +1 more source

Realistic CT image simulation tools for laboratory based X-ray CT at UGCT [PDF]

, 2013
In laboratory based X-ray Computed Tomography (CT), the grey values in the resulting CT image depend on several scanning conditions such as the emitted spectrum, the response characteristics of the detector and beam filtration.
Brabant, Loes, Dierick, Manuel, Pauwels, Elin, Van Hoorebeke, Luc   +3 more
core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Two-view topogram-based anatomy-guided CT reconstruction for prospective risk minimization

Scientific Reports
To facilitate a prospective estimation of the effective dose of an CT scan prior to the actual scanning in order to use sophisticated patient risk minimizing methods, a prospective spatial dose estimation and the known anatomical structures are required.
Chang Liu, Laura Klein, Yixing Huang, Edith Baader, Michael Lell, Marc Kachelrieß, Andreas Maier   +6 more
doaj   +1 more source

X-ray Digital Radiography and Computed Tomography

Journal of Imaging, 2022
In recent years, X-ray imaging has rapidly grown and spread beyond the medical field; today, it plays a key role in diverse research areas [...]
Maria Pia Morigi, Fauzia Albertin
doaj   +1 more source

A Convex Reconstruction Model for X-ray Tomographic Imaging with Uncertain Flat-fields [PDF]

, 2017
Classical methods for X-ray computed tomography are based on the assumption that the X-ray source intensity is known, but in practice, the intensity is measured and hence uncertain.
Aggrawal, Hari Om, Andersen, Martin Skovgaard, Rose, Sean, Sidky, Emil Y.   +3 more
core   +2 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

WEST tokamak hard x-ray tomography inversion

AIP Advances, 2021
Long-pulse steady-state discharges with lower hybrid current drive were successfully obtained in the limiter configuration machine, Tore Supra. The hard x-ray (HXR) diagnostic system in Tore Supra associated with tomographic inversion provided a good ...
K. Wongrach, D. Mazon, J. Morales, L. Fleury, R. Picha, J. Promping   +5 more
doaj   +1 more source