Results 61 to 70 of about 70,449 (261)
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Two-view topogram-based anatomy-guided CT reconstruction for prospective risk minimization
Scientific ReportsTo facilitate a prospective estimation of the effective dose of an CT scan prior to the actual scanning in order to use sophisticated patient risk minimizing methods, a prospective spatial dose estimation and the known anatomical structures are required.
Chang Liu +6 more
doaj +1 more source
X-ray induced acoustic computed tomography
Photoacoustics, 2020 X-ray imaging has proved invaluable in medical diagnoses and non-destructive testing (NDT) in the past century. However, there remain two major limitations: radiation harm and inaccessibility to the sample.
P. Samant, L. Trevisi, X. Ji, L. Xiang
doaj +1 more source
X-ray computed tomography for composites
, 2014 Presentation made at the 53rd Annual Conference of the British Institute of Non-Destructive Testing at Manchester on September 10 2014.
Léonard, Fabien +3 more
openaire +2 more sources
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Analyses non destructives par tomographie à rayons X
Les Nouvelles de l’Archéologie, 2020 X-ray imaging techniques benefit from developments in physics, mathematics, and computer science, and provide analytical tools to study 3D internal structures of a wide range of objects.
Patricia Wils
doaj +1 more source
Ground-truth verification of dynamic x-ray micro-tomography images of fluid displacement
, 2012 X-ray micro computed tomography (jtCT) is a method of choice for the non-destructive imaging of static 3d samples. A fundamental constraint of conventional X-ray jtCT is that the sample must remain static during data acquisition.
Sheppard, Adrian +9 more
core +1 more source
Computed tomography-osteoabsorptiometry for assessing the density distribution of subchondral bone as a measure of long-term mechanical adaptation in individual joints [PDF]
, 1989 To estimate subchondral mineralisation patterns which represent the long-term loading history of individual joints, a method has been developed employing computed tomography (CT) which permits repeated examination of living joints.
Müller-Gerbl, Magdalena +4 more
core +1 more source
, 2022 S.143-184In this chapter, an identification and classification of influence factors in X-ray computed tomography metrology is given. A description of image artefacts commonly encountered in industrial X-ray computed tomography is presented together with ...
Kasperl, S., Chiffre, L. de, Stolfi, A.
core +1 more source