THE MEIOTIC BEHAVIOR OF GROSSLY DELETED X CHROMOSOMES IN DROSOPHILA MELANOGASTER [PDF]
, 1958 Dan L. Lindsley, L Sandler
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Advanced Functional Materials, EarlyView.A biofabricated 3D in vitro model recapitulating endochondral ossification (ECO) is described, mimicking the steps from condensation to chondrogenesis and hypertrophy, culminating with vascularization of the hypertrophic construct. As a model proof of concept application, Ewing Sarcoma cells are seeded in the model, showing modifications in their ...
Maria Vittoria Colombo +13 more
wiley +1 more source
A FURTHER ANALYSIS OF LOCI IN THE SO-CALLED "INERT REGION" OF THE X CHROMOSOME OF DROSOPHILA [PDF]
, 1937 Hermann J. Müller +3 more
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Versatile Cell Penetrating Peptide for Multimodal CRISPR Gene Editing in Primary Stem Cells
Advanced Functional Materials, EarlyView.CRISPR machinery in diverse molecular formats (DNA, RNA, and ribonucleic protein) is complexed into nanoparticles with the cell‐friendly arginine‐alanine‐leucine‐alanine (RALA) cell‐penetrating peptide. Nanoparticles are delivered to primary mesenchymal stem cells ex vivo or locally in vivo to facilitate multimodal CRISPR gene editing. This RALA‐CRISPR
Joshua P. Graham +9 more
wiley +1 more source
PROOF THAT THE ENTIRE CHROMOSOME IS NOT ELIMINATED IN THE PRODUCTION OF SOMATIC VARIATIONS BY X-RAYS IN DROSOPHILA [PDF]
, 1930 J. T. Patterson
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3D Multicellular Scaffold Based Model for Advancing Bone Disorder Research
Advanced Functional Materials, EarlyView.A scalable 3D multicellular in vitro bone model engineered by integrating osteoblasts, osteoclasts, and endothelial cells on biodegradable scaffolds. The system recapitulates key features of human bone remodeling and disease pathology. As a proof of concept, the model mimics osteogenesis imperfecta, demonstrating its potential as a physiologically ...
Gali Guterman‐Ram +5 more
wiley +1 more source
CROSSING OVER NEAR THE SPINDLE ATTACHMENT OF THE X CHROMOSOMES IN ATTACHED-X TRIPLOIDS OF DROSOPHILA MELANOGASTER [PDF]
, 1935 G W Beadle
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Elastic Energy Storage in Biological Materials: Internal Stresses and Their Functionality
Advanced Materials, EarlyView.Harnessing and storing internally generated elastic energy is a clever strategy by biological materials to perform functions like shape transformation, movement, and predation. This review explores how biological systems manipulate mechanisms like atomic or protein integration into minerals, protein conformational shifts, phase transitions, and osmotic
Shahrouz Amini +3 more
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The distribution of polygenic activity on the X-chromosome of Drosophila melanogaster [PDF]
, 1949 L. G. Wigan
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Probiotic‐Based Materials as Living Therapeutics
Advanced Materials, EarlyView.Recent advances in Engineered Living Materials are highlighted, integrating synthetic biology and advanced materials, with a focus on probiotic‐based therapeutics. Probiotic Living Materials hold great potential for biosensing, infection treatment, osteogenesis, wound healing, vaginal and gastrointestinal disorders, and cancer therapy. breakthroughs in
Laura Sabio +2 more
wiley +1 more source