Results 271 to 280 of about 317,261 (329)

Unraveling the role of Xist in X chromosome inactivation: insights from rabbit model and deletion analysis of exons and repeat A. [PDF]

Cell Mol Life Sci
Liang M, Zhang L, Lai L, Li Z.
europepmc   +1 more source

Quantification of escape from X chromosome inactivation with single-cell omics data reveals heterogeneity across cell types and tissues. [PDF]

Cell Genom
Tomofuji Y, Edahiro R, Sonehara K, Shirai Y, Kock KH, Wang QS, Namba S, Moody J, Ando Y, Suzuki A, Yata T, Ogawa K, Naito T, Namkoong H, Xuan Lin QX, Buyamin EV, Tan LM, Sonthalia R, Han KY, Tanaka H, Lee H, Asian Immune Diversity Atlas (AIDA) Network, Japan COVID-19 Task Force, Biobank Japan Project, Okuno T, Liu B, Matsuda K, Fukunaga K, Mochizuki H, Park WY, Yamamoto K, Hon CC, Shin JW, Prabhakar S, Kumanogoh A, Okada Y.   +35 more
europepmc   +1 more source

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Regulation of X-chromosome inactivation by the X-inactivation centre

Nature Reviews Genetics, 2011
X-chromosome inactivation (XCI) ensures dosage compensation in mammals and is a paradigm for allele-specific gene expression on a chromosome-wide scale. Important insights have been made into the developmental dynamics of this process. Recent studies have identified several cis- and trans-acting factors that regulate the initiation of XCI via the X ...
Sandrine Augui, E. Nora, E. Heard
semanticscholar   +5 more sources

Gene regulation in time and space during X-chromosome inactivation

Nature Reviews Molecular Cell Biology, 2022
A. Loda, Samuel Collombet, E. Heard
semanticscholar   +3 more sources

Requirement for Xist in X chromosome inactivation

Nature, 1996
Graeme D. Penny, G. Kay, S. Sheardown, S. Rastan, N. Brockdorff   +4 more
semanticscholar   +3 more sources

X-chromosome inactivation: counting, choice and initiation

Nature Reviews Genetics, 2001
P. Avner, E. Heard
semanticscholar   +3 more sources

Gene silencing in X-chromosome inactivation: advances in understanding facultative heterochromatin formation

Nature Reviews Genetics, 2011
A. Wutz
semanticscholar   +3 more sources

X-Chromosome Inactivation

2013
The dimorphism of the sex chromosomes has led to some of the most dramatic epigenetic phenomena known in order to achieve dosage compensation between the sexes. Mammalian X-chromosome inactivation (XCI) requires the differential treatment of two essentially identical chromosomes in the same nuclear environment.
Wendy P. Robinson, Allison M. Cotton, Maria S. Peñaherrera, Samantha B. Peeters, Carolyn J. Brown   +4 more
openaire   +2 more sources

Mammalian X Chromosome Inactivation

1992
The initial step in mammalian sexual differentiation is based on the XX: XY chromosomal system. In order to function properly, this chromosomal mechanism must be regulated to eliminate the aneuploidy effects in somatic tissues and still insure normal sexual differentiation and development.
S M, Gartler, K A, Dyer, M A, Goldman
openaire   +2 more sources

Digging into X chromosome inactivation

Science, 2021
Characterizing X chromosome inactivation in nonhuman primates reveals some ...
Rougeulle, C., Heard, Edith
openaire   +3 more sources