Results 1 to 10 of about 38,995 (265)

The effect of X-linked dosage compensation on complex trait variation

Nature Communications, 2019
Dosage compensation (DC) on the X chromosome has predictable effects on genetic and phenotypic trait variance. Here, the authors use information for 20 quantitative traits in the UK Biobank and across-tissue gene expression to compare X-linked ...
Julia Sidorenko, Irfahan Kassam, Kathryn E. Kemper, Jian Zeng, Luke R. Lloyd-Jones, Grant W. Montgomery, Greg Gibson, Andres Metspalu, Tonu Esko, Jian Yang, Allan F. McRae, Peter M. Visscher   +11 more
doaj   +1 more source

Influence of homoeologous chromosomes on gene-dosage effects in allohexaploid wheat (Triticum aestivum L.)

, 1978
Gene-dosage responses for a group of six wheat endosperm proteins have been investigated by using compensated nulli-tetrasomic lines of cv. Chinese Spring. Practically linear dosage responses have been observed for all the proteins.
Aragoncillo Ballesteros, Cipriano, Rodriguez Loperena, M.A., Salcedo Duran, Gabriel, Carbonero Zalduegui, Pilar, García Olmedo, Francisco   +4 more
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Conflict on the sex chromosomes: cause, effect, and complexity [PDF]

, 2014
Intralocus sexual conflict and intragenomic conflict both affect sex chromosome evolution and can in extreme cases even cause the complete turnover of sex chromosomes.
Hosken, DJ, Mank, JE, Wedell, N
core   +1 more source

Relationships between cell cycle regulator gene copy numbers and protein expression levels in Schizosaccharomyces pombe. [PDF]

PLoS ONE, 2013
We previously determined the copy number limits of overexpression for cell division cycle (cdc) regulatory genes in the fission yeast Schizosaccharomyces pombe using the "genetic tug-of-war" (gTOW) method.
Ayako Chino, Koji Makanae, Hisao Moriya
doaj   +1 more source

Expression of homoeologous molecular systems in wheat alloploids [PDF]

, 1976
Allopolyploidy is widespread in the plant kingdom, where it has been of considerable evolutionary significance. Although the existence of heterotic interactions between the genomes that make up an alloploid have been generally assumed, the precise nature
Aragoncillo Ballesteros, Cipriano, Carbonero Zalduegui, Pilar, Fernandez de Caleya, R., García Olmedo, Francisco, Torres, V.   +4 more
core   +1 more source

Investigating the mechanism behind the feedback regulation of the Exon Junction Complex component MAGOH [PDF]

, 2020
RNA binding proteins are critical for regulation of RNA function, and therefore maintaining appropriate levels of these proteins is important for cellular regulation.
Nega, Abigail
core  

How to make a sex chromosome [PDF]

, 2016
Sex chromosomes can evolve once recombination is halted between a homologous pair of chromosomes. Owing to detailed studies using key model systems, we have a nuanced understanding and a rich review literature of what happens to sex chromosomes once ...
A Auton, A Auton, A Burt, A Kong, A McNair, AE Wright, AE Wright, AG Hinch, AK Chippindale, AST Papadopulos, B Charlesworth, B Charlesworth, B Charlesworth, B Charlesworth, B Lemos, B Payer, B Vicoso, B Vicoso, B Vicoso, BT Lahn, C Dufresnes, C Kupper, C Lemaitre, C Mullon, D Bachtrog, D Bachtrog, D Bachtrog, D Bachtrog, D Bachtrog, D Charlesworth, D Charlesworth, D Charlesworth, E Suomalai, ED Parvanov, F Baudat, GS van Doorn, GS van Doorn, H Muller, H Skaletsky, H Wallace, HK Moghadam, HM Natri, I Miura, IL Berg, J Haldane, J Hough, J Ironside, J Kitano, J Lange, J Wang, JA Tennessen, JE Mank, JE Mank, JE Mank, JE Mank, JF Flot, JL Feder, JP Wang, JR Ser, K Choi, K Matsubara, LB Koerich, LD Brooks, M Joron, M Nakamura, M Roesti, M Rovatsos, M Stock, M Stock, M White, MA Wilson, MG Poggio, MJ Wyman, MJD White, MT Ross, MV Chibalina, N Perrin, Q Zhou, Q Zhou, Q Zhou, R Bergero, R Bergero, R Bergero, R Bergero, R Gorelick, R Ming, RA Fisher, RB Roberts, RB Spigler, RS Pandey, S Ahmed, S Grozeva, S Lamichhaney, S Myers, S Myers, S Naurin, S Nokkala, S Singhal, S Yoshimoto, SS Renner, T Dobzhansky, T Dobzhansky, T Dobzhansky, T Gamble, T Kamiya, T Lenormand, T Lenormand, T Morgan, VB Bardella, WR Rice, WR Rice, YQS Soh, ZY Liu, Ö Winge   +113 more
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Theoretical and empirical comparisons of expected and realized relationships for the X-chromosome

Genetics Selection Evolution, 2020
Background X-chromosomal loci present different inheritance patterns compared to autosomal loci and must be modeled accordingly. Sexual chromosomes are not systematically considered in whole-genome relationship matrices although rules based on ...
Tom Druet, Andres Legarra
doaj   +1 more source

Genome-Wide Effects on Gene Expression Between Parental and Filial Generations of Trisomy 11 and 12 of Rice

Rice, 2023
Aneuploid refers to the gene dosage imbalance due to copy number alterations. Aneuploidy is generally harmful to the growth, development and reproduction of organisms according to the numerous research.
Shang Sun, Kai Liu, Chao Xue, Yingying Hu, Hengxiu Yu, Guoxiao Qi, Jijin Chen, Xiya Li, Xinru Zhao, Zhiyun Gong   +9 more
doaj   +1 more source

Transcriptional effects of gene dose reduction [PDF]

, 2014
Large-scale gene dose reductions usually lead to abnormal phenotypes or death. However, male mammals, Drosophila, and Caenorhabditis elegans have only one X chromosome and thus can be considered as monosomic for a major chromosome.
Brian Oliver, Hina Sultana, Kseniya Golovnina, Satish Kumar, Zhen-Xia Chen   +4 more
core   +1 more source