Results 11 to 20 of about 2,582,389 (248)
General lack of global dosage compensation in ZZ/ZW systems? Broadening the perspective with RNA-seq [PDF]
BMC Genomics, 2011 Background Species with heteromorphic sex chromosomes face the challenge of large-scale imbalance in gene dose. Microarray-based studies in several independent male heterogametic XX/XY systems suggest that dosage compensation mechanisms are in place to ...
Wolf Jochen BW, Bryk Jarosław
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, 2010 2010, 1st quarter-; At head of title: Ohio Deferred Compensation.; "A publication of the Ohio Deferred Compensation Board.
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The epigenome of evolving Drosophila neo-sex chromosomes: dosage compensation and heterochromatin formation. [PDF]
PLoS Biology, 2013 Sex chromosomes originated from autosomes but have evolved a highly specialized chromatin structure. Drosophila Y chromosomes are composed entirely of silent heterochromatin, while male X chromosomes have highly accessible chromatin and are ...
Qi Zhou +5 more
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Genetic compensation: A phenomenon in search of mechanisms. [PDF]
PLoS Genetics, 2017 Several recent studies in a number of model systems including zebrafish, Arabidopsis, and mouse have revealed phenotypic differences between knockouts (i.e., mutants) and knockdowns (e.g., antisense-treated animals).
Mohamed A El-Brolosy +1 more
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Computational and Structural Biotechnology Journal, 2020 Hereditary diseases and complex traits often manifest in specific tissues, whereas their causal genes are expressed in many tissues that remain unaffected.
Juman Jubran +3 more
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Chromatin accessibility, not 5mC methylation covaries with partial dosage compensation in crows.
PLoS Genetics, 2023 The evolution of genetic sex determination is often accompanied by degradation of the sex-limited chromosome. Male heterogametic systems have evolved convergent, epigenetic mechanisms restoring the resulting imbalance in gene dosage between diploid ...
Ana Catalán +3 more
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Sex-specific trans-regulatory variation on the Drosophila melanogaster X chromosome. [PDF]
PLoS Genetics, 2015 The X chromosome constitutes a unique genomic environment because it is present in one copy in males, but two copies in females. This simple fact has motivated several theoretical predictions with respect to how standing genetic variation on the X ...
Michael Stocks +3 more
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Identification of chromatin-associated regulators of MSL complex targeting in Drosophila dosage compensation. [PDF]
PLoS Genetics, 2012 Sex chromosome dosage compensation in Drosophila provides a model for understanding how chromatin organization can modulate coordinate gene regulation. Male Drosophila increase the transcript levels of genes on the single male X approximately two-fold to
Erica Larschan +9 more
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Dosage compensation in birds [PDF]
, 2001 The Z and W sex chromosomes of birds have evolved independently from the mammalian X and Y chromosomes [1]. Unlike mammals, female birds are heterogametic (ZW), while males are homogametic (ZZ).
Bird, Adrian P +14 more
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PLoS Genetics, 2020 Proper control of gene expression levels upon various perturbations is a fundamental aspect of cellular robustness. Protein-level dosage compensation is one mechanism buffering perturbations to stoichiometry of multiprotein complexes through accelerated ...
Koji Ishikawa +2 more
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