Results 281 to 290 of about 90,734 (327)

Palladium compounds of xanthine and xanthine derivatives

Inorganica Chimica Acta, 1983
The biological importance of purine bases is well known. The interaction of metal ions with nucleic acids, nucleotides and nucleotides has been an active area of inorganic and structural chemistry during the last few years, and a number of recent reviews exist on the subject [1, 2].
E. Colacio, Manuel Nogueras, M.A. Romero, Juan M. Salas, Adolfo Sánchez   +4 more
openaire   +2 more sources

Mammalian xanthine oxidoreductase – mechanism of transition from xanthine dehydrogenase to xanthine oxidase

The FEBS Journal, 2008
Reactive oxygen species are generated by various biological systems, including NADPH oxidases, xanthine oxidoreductase, and mitochondrial respiratory enzymes, and contribute to many physiological and pathological phenomena. Mammalian xanthine dehydrogenase (XDH) can be converted to xanthine oxidase (XO), which produces both superoxide anion and ...
Takeshi Nishino, Tomoko Nishino, Bryan T. Eger, Emil F. Pai, Ken Okamoto   +4 more
openaire   +3 more sources

Xanthine urolithiasis

Urology, 2006
Xanthine calculi are uncommonly encountered stones. When they occur, they typically do so in association with inborn metabolic disorders such as hereditary xanthinuria or Lesch-Nyhan syndrome. They may also occur in association with states of profound hyperuricemia such as myeloproliferative disease after treatment with allopurinol.
Vernon M, Pais, Gregory, Lowe, Costas D, Lallas, Glenn M, Preminger, Dean G, Assimos   +4 more
openaire   +2 more sources

Xanthine oxidase and xanthine dehydrogenase

The FASEB Journal, 1995
Xanthine oxidase and xanthine dehydrogenase are enzymes involved in the metabolism of purines and pyrimidines in various organisms. Their relationship to one another has been the subject of considerable debate, primarily because of their proposed roles in ischemia/reperfusion damage in tissues.
Takeshi Nishino, Russ Hille
openaire   +3 more sources

Novel insights into the inhibitory mechanism of kaempferol on xanthine oxidase.

Journal of Agricultural and Food Chemistry, 2015
Xanthine oxidase (XO), a key enzyme in purine catabolism, is widely distributed in human tissues. It can catalyze xanthine to generate uric acid and cause hyperuricemia and gout.
Yajie Wang, Guowen Zhang, Jun-hui Pan, D. Gong   +3 more
semanticscholar   +1 more source

Regulation of xanthine dehydrogenase and xanthine oxidase activity by hypoxia

American Journal of Physiology-Lung Cellular and Molecular Physiology, 1996
The present study determined the effect of hypoxia on xanthine dehydrogenase (XDH) and xanthine oxidase (XO) activity and gene and protein expression in cultured bovine aortic endothelial cells (BAEC). BAEC were exposed to hypoxia (3% O2) or anoxia (0% O2) for 24 or 48 h and to 24 h of hypoxia followed by 24 h of reoxygenation.
T. P. Huecksteadt, W. B. Poss, P. C. Panus, John R. Hoidal, B. A. Freeman   +4 more
openaire   +3 more sources

Non-Enzymatic Electrochemical Sensor for the Simultaneous Determination of Xanthine, its Methyl Derivatives Theophylline and Caffeine as well as its Metabolite Uric Acid

, 2017
Xanthine and its methyl derivatives, theophylline and caffeine are purines which find important roles in biological systems. The simultaneous voltammetric behaviour of these purines has been studied on a glassy carbon electrode modified with an ...
S. Jesny, K. D. Kumar
semanticscholar   +1 more source

Dietary Flavonoids as Xanthine Oxidase Inhibitors: Structure-Affinity and Structure-Activity Relationships.

Journal of Agricultural and Food Chemistry, 2015
The flavonoid family has been reported to possess a high potential for inhibition of xanthine oxidase (XO). This study concerned the structural aspects of inhibitory activities and binding affinities of flavonoids as XO inhibitors.
Suyun Lin, Guowen Zhang, Yi-jing Liao, Jun-hui Pan, D. Gong   +4 more
semanticscholar   +1 more source

Ischaemic Brain Oedema and Xanthine-Xanthine Oxidase System

1990
The formation of oxygen-derived free radicals in cerebral ischaemia has been implicated in altering the BBB permeability, cause oedema and tissue damage. However little attention has been paid regarding the involvement of xanthine oxidase in the cerebral ischaemic events.
Masatsune Ishikawa, Haruhiko Kikuchi, Kinuta Y   +2 more
openaire   +2 more sources

Structure-activity relationship and classification of flavonoids as inhibitors of xanthine oxidase and superoxide scavengers.

Journal of Natural Products, 1998
The structure-activity relationship of flavonoids as inhibitors of xanthine oxidase and as scavengers of the superoxide radical, produced by the action of the enzyme xanthine oxidase, was investigated.
P. Cos, Li Ying, M. Calomme, Jia P. Hu, K. Cimanga, B. V. Poel, L. Pieters, A. Vlietinck, D. V. Berghe   +8 more
semanticscholar   +1 more source