Results 271 to 280 of about 299,059 (319)

Role of xanthine-oxidase system in mucosal injury after intestinal preservation and transplantation [PDF]

, 1993
Hamamoto, I, Kokudo, K, Starzl, TE, Todo, S, Zhang, S   +4 more
core  

Xanthine oxidase inhibition study of isolated secondary metabolites from Dolichandrone spathacea (Bignoniaceae): In vitro and in silico approach. [PDF]

Saudi Pharm J
Nguyen DK, Liu TW, Hsu SJ, Huynh QT, Thi Duong TL, Chu MH, Wang YH, Vo TH, Lee CK.   +8 more
europepmc   +1 more source

Effect of the Xanthine Oxidase Inhibitor, Febuxostat, on WBC Count in Asymptomatic Hyperuricemia: Subanalysis of the Randomized PRIZE Study. [PDF]

J Atheroscler Thromb
Takeshita M, Tanaka A, Yoshida H, Nakamura I, Shibata Y, Hata S, Kushiyama A, Okutsu M, Ishizu T, Node K.   +9 more
europepmc   +1 more source

Inhibition of xanthine oxidase alleviated pancreatic necrosis via HIF-1α-regulated LDHA and NLRP3 signaling pathway in acute pancreatitis. [PDF]

Acta Pharm Sin B
Rong J, Han C, Huang Y, Wang Y, Qiu Q, Wang M, Wang S, Wang R, Yang J, Li X, Hu C, Chen Z, Deng L, Huang W, Xia Q, Du D.   +15 more
europepmc   +1 more source

Density functional theory (DFT), molecular docking, and xanthine oxidase inhibitory studies of dinaphthodiospyrol S from Diospyros kaki L. [PDF]

Saudi Pharm J
Abu-Izneid T, Rauf A, Ahmad Z, Wadood A, Ayub K, Muhammad N, Al-Awthan YS, Maqbool M, Bahattab OS, Hemeg HA, Naz S, Formanowicz D.   +11 more
europepmc   +1 more source

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Natural compounds with xanthine oxidase inhibitory activity: A review

Chemical Biology and Drug Design, 2019
Hyperuricemia (HUA), a disease due to an elevation of body uric acid level and responsible for various diseases such as gout, cardiovascular disorders, and renal failure, is a major ground debate for the medical science these days.
A. Mehmood, M. Ishaq, Lei Zhao, Bushra Safdar, A. Rehman, Masooma Munir, A. Raza, M. Nadeem, W. Iqbal, Chengtao Wang   +9 more
semanticscholar   +1 more source

Sulfhydryl oxidase-catalyzed conversion of xanthine dehydrogenase to xanthine oxidase

Archives of Biochemistry and Biophysics, 1981
Abstract Xanthine oxidase may be isolated from various mammalian tissues as one of two interconvertible forms, viz., a dehydrogenase (NAD+ dependent, form D) or an oxidase (O2 utilizing, form O). A crude preparation of rat liver xanthine dehydrogenase (form D) was treated with an immobilized preparation of crude bovine sulfhydryl oxidase.
Debra A. Clare, Barbara A. Blakistone, H.Robert Horton, Harold E. Swaisgood   +3 more
openaire   +3 more sources

The reactions of chloroperoxidase in the presence of xanthine/xanthine oxidase

Biochemical and Biophysical Research Communications, 1989
Spectral data are presented which indicate that chloroperoxidase is converted to compound II during the reaction with superoxide/hydrogen peroxide generated in the xanthine/xanthine oxidase system. Upon completion of compound II formation, compound II returns back to the native state of chloroperoxidase without formation of detectable intermediates. It
H. Brian Dunford, Diana Metodiewa, Michael A. Pickard   +2 more
openaire   +3 more sources

Novel insights into the inhibitory mechanism of kaempferol on xanthine oxidase.

Journal of Agricultural and Food Chemistry, 2015
Xanthine oxidase (XO), a key enzyme in purine catabolism, is widely distributed in human tissues. It can catalyze xanthine to generate uric acid and cause hyperuricemia and gout.
Yajie Wang, Guowen Zhang, Jun-hui Pan, D. Gong   +3 more
semanticscholar   +1 more source