Results 61 to 70 of about 6,787 (215)

Cytotoxicity and Toxicity Evaluation of Xanthone Crude Extract on Hypoxic Human Hepatocellular Carcinoma and Zebrafish (Danio rerio) Embryos

open access: yesToxics, 2018
Xanthone is an organic compound mostly found in mangosteen pericarp and widely known for its anti-proliferating effect on cancer cells. In this study, we evaluated the effects of xanthone crude extract (XCE) and α-mangostin (α-MG) on normoxic
Shazrul Fazry   +13 more
doaj   +1 more source

Molecular Cloning and Characterization of a Xanthone Prenyltransferase from Hypericum calycinum Cell Cultures

open access: yesMolecules, 2015
In plants, prenylation of metabolites is widely distributed to generate compounds with efficient defense potential and distinct pharmacological activities profitable to human health. Prenylated compounds are formed by members of the prenyltransferase (PT)
Tobias Fiesel   +8 more
doaj   +1 more source

Tetraoxygenated naturally occurring xanthones

open access: yesPhytochemistry, 2000
This review, with 350 references, gives information on the chemical study of 234 naturally occurring tetraoxygenated xanthones in 12 families, 53 genus and 182 species of higher plants, and two which are described as fungal and lichen metabolites. The value of these groups of substances in connection with pharmacological activity and therapeutic use of
V, Peres, T J, Nagem, F F, de Oliveira
openaire   +3 more sources

Xanthone-boronic acids: An insight into the synthesis of borylated xanthone derivates

open access: yes, 2023
CHARLES UNIVERSITY FACULTY OF PHARMACY IN HRADEC KRÁLOVÉ DEPARTMENT OF PHARMACEUTICAL CHEMISTRY AND PHARMACEUTICAL ANALYSIS DIPLOMA THESIS XANTHONE-BORONIC ACIDS: AN INSIGHT INTO THE SYNTHESIS OF BORYLATED XANTHONE DERIVATIVES Supervisor: prof.
Houngbedji, Priam-Amedeo
core  

Biological activity, quantitative structure–activity relationship analysis, and molecular docking of xanthone derivatives as anticancer drugs

open access: yesDrug Design, Development and Therapy, 2018
Isnatin Miladiyah,1,2 Jumina Jumina,3 Sofia Mubarika Haryana,4 Mustofa Mustofa5 1Pharmacology Department, Faculty of Medicine, Islamic University of Indonesia, 2Doctorate Program of Medical Science and Health, Faculty of Medicine, 3Chemistry Department,
Miladiyah I   +3 more
doaj  

ANTIBACTERIAL ACTIVITY OF XANTHONE FROM ETHYL ACETATE EXTRACT OF THE STEAM BARK OF Garcinia picrorrhiza Miq

open access: yesAlchemy, 2017
A compound was isolated from the ethyl acetate extract of stem bark Garcinia picrorrhiza. The extraction was conducted by maseration. Separation and purification were done by chromatography method.
Muharni Muharni   +2 more
doaj   +1 more source

Xanthone-boronic acids: An insight into the synthesis of borylated xanthone derivates

open access: yes, 2021
CHARLES UNIVERSITY FACULTY OF PHARMACY IN HRADEC KRÁLOVÉ DEPARTMENT OF PHARMACEUTICAL CHEMISTRY AND PHARMACEUTICAL ANALYSIS DIPLOMA THESIS XANTHONE-BORONIC ACIDS: AN INSIGHT INTO THE SYNTHESIS OF BORYLATED XANTHONE DERIVATIVES Supervisor: prof.
Houngbedji, Priam-Amedeo
core  

Discovery of a New Xanthone against Glioma: Synthesis and Development of (Pro)liposome Formulations

open access: yesMolecules, 2019
Following our previous work on the antitumor activity of acetylated flavonosides, a new acetylated xanthonoside, 3,6-bis(2,3,4,6-tetra-O-acetyl-β-glucopyranosyl)xanthone (2), was synthesized and discovered as a potent inhibitor of tumor cell growth.
Ana Alves   +10 more
doaj   +1 more source

Antitumor Activity of Some Prenylated Xanthones [PDF]

open access: yesPharmaceuticals, 2009
Pyranoxanthones 6-8 were obtained by dehydrogenation of the respective dihydropyranoxanthones 3-5 with DDQ in dry dioxane. Two prenylated xanthones 10,11 were obtained from the reaction of 1-hydroxyxanthone (9) with prenyl bromide in alkaline medium, or by condensation of xanthone 9 with isoprene in the presence of orthophosphoric acid.
Raquel A.P. Castanheiro   +4 more
openaire   +4 more sources

Ceramidonines, Fused 3,9‐Diazaperylenes, and Related Compounds: From Synthesis to Physicochemical Properties and Evaluation as Inhibitors of PIM Kinases

open access: yesChemistryEurope, Volume 4, Issue 5, May 2026.
Ceramidonines, benzo‐fused 3,9‐diazaperylenes and related compounds were synthesized, and their properties studied. Substituted ceramidonines were synthesized by cyclization of 1‐(arylamino)anthraquinones under acidic conditions. These key intermediates were prepared either by copper‐promoted N‐arylation of 1‐aminoanthraquinone with iodoarenes or, more
Ahlem N. Khelf‐Maghraoui   +15 more
wiley   +1 more source

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