Results 61 to 70 of about 4,599 (180)

Effect of Xanthone Derivatives on Animal Models of Depression

Current Therapeutic Research, 2014
Background: Extracts of the plant Hypericum perforatum L. have been traditionally used in folk medicine for the treatment of depressive disorders. Xanthone, a component of Hypericum perforatum L., has been shown to be effective in animal models of ...
Xu Zhao, MD, Qunying Chen, MD, Yuan Liu, BS, Chao Xia, BS, Jincheng Shi, MD, Maqing Zheng, PhD   +5 more
doaj   +1 more source

Tablet Formulation Containing Chitosan-Alginate Microparticles: Characterization and Release Profile of Xanthones

International Journal of Technology, 2020
Mangosteen pericarp extract contains a high amount of xanthones, which are secondary plant metabolites that exhibit high antioxidant activities as well as beneficial pharmacological properties, but low bioavailabilities.
Elsa Anisa Krisanti, David Lazuardi, Kianti Kasya Kiresya, Kamarza Mulia   +3 more
doaj   +1 more source

Anti-Tumor Xanthones from Garcinia nujiangensis Suppress Proliferation, and Induce Apoptosis via PARP, PI3K/AKT/mTOR, and MAPK/ERK Signaling Pathways in Human Ovarian Cancers Cells

Drug Design, Development and Therapy, 2020
Zhongyan Tang,1,* Lihua Lu,2,* Zhengxiang Xia3 1Department of Emergency and Critical Care Medicine, Jin Shan Hospital, Fudan University, Shanghai 201508, People’s Republic of China; 2Department of Neonatology, International Peace Maternity and ...
Tang Z, Lu L, Xia Z
doaj  

Antioxidants and Anticholinesterase Activities of the Characterized Ethanolic of Ripe Sesoot (Garcinia picrorrhiza Miq.) Fruit Extract (GpKar) and Xanthone

Majalah Obat Tradisional, 2017
Oxidative stress has been known to contribute to Alzheimer’s disease. Acetylcholinesterase (AChE) enzyme may lead to Alzheimer’s disease as a neurotransmitter.
Sri Utami, Pratami Adityaningsari, Insan Sosiawan, Susi Endrini, Qomariyah Romadhiyani Sachrowardi, Sonny Pamudji Laksono, Said Nafik, Betharie Cendera Arrahmani, Ervi Afifah, Wahyu Widowati   +9 more
doaj   +1 more source

Borylcyclopropanes: Synthetic Strategies and Applications

Angewandte Chemie, Volume 138, Issue 37, 7 September 2026.
Borylcyclopropanes (cyclopropanes bearing a boron substituent) sit at the intersection of two privileged frameworks in synthesis. This review provides the first exhaustive survey of their chemistry, spanning metal–carbene, nucleophilic cyclization, radical, hydroboration, and C─H activation routes, and documenting applications in medicinal chemistry ...
Aiza A. Butt, Joseph M. Ready
wiley   +1 more source

Preparation and characterization of mangiferin-loaded lipid nanocapsules

Archives of Pharmaceutical Sciences Ain Shams University, 2023
Mangiferin (Mgf), a xanthone glucoside of natural origin, is well known to possess different pharmacological actions such as analgesic, antiviral, antidiabetic, anti-inflammatory, hepatoprotective, and antitumor. However, concerning water solubility it
Sara S. Barakat, Maha S. Nasr , Sabry S. Badawy, Nahed D. Mortada   +3 more
doaj  

Prenylates Xanthones from Garcinia xanthochymus.

ChemInform, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
Chanmahasathien, Wisinee, Li, Yushan, Satake, Masayuki, Oshima, Yasukatsu, Ishibashi, Masami, Ruangrungsi, Nijsiri, Ohizumi, Yasushi   +6 more
openaire   +3 more sources

Xanthones and Cancer

, 2020
Xanthones are a class of heterocyclic natural products that have been widely studied for their pharmacological potential. In fact, they have been serving as scaffolds for the design of derivatives focusing on drug development. One of the main study targets of xanthones is their anticancer activity. Several compounds belonging to this class have already
Klein-Júnior, Luiz C, Campos, Adriana, Niero, Rivaldo, Corrêa, Rogério, Yvan, Vander Heyden, Filho, Valdir Cechinel   +5 more
openaire   +1 more source

Determinação da constante de velocidade absoluta para a reação de abstração de hidrogênio fenólico pelo estado excitado triplete de xantona em acetonitrila e no líquido iônico hexafluorfosfato de 1-butil-3-metil-imidazólio [bmim.PF6]

Química Nova, 2013
The triplet excited state of xanthone was generated and characterized by laser flash photolysis in acetonitrile (λmax=620 nm; t=1.8 ms) and in ionic liquid 1-butyl-3-methylimidazolium hexafluorophosphate [bmim.PF6] (λmax=620 nm; t=3.0 ms). It reacts with
Ada Ruth Bertoti, José Carlos Netto-Ferreira   +1 more
doaj   +1 more source

Transcription profiling of the Neurospora crassa response to a group of synthetic (thio)xanthones and a natural acetophenone

Genomics Data, 2015
Xanthones are a class of heterocyclic compounds characterized by a dibenzo-γ-pyrone nucleus. Analysis of their mode of action in cells, namely uncovering alterations in gene expression, is important because these compounds have potential therapeutic ...
A. Pedro Gonçalves, Nuno Silva, Carla Oliveira, David J. Kowbel, N. Louise Glass, Anake Kijjoa, Andreia Palmeira, Emília Sousa, Madalena Pinto, Arnaldo Videira   +9 more
doaj   +1 more source