Results 111 to 120 of about 26,824 (211)

Peroxiredoxin 4 Involved in Spermatogenesis by Affecting Oxidative Stress and Ferroptosis

open access: yesAndrology, EarlyView.
ABSTRACT Background The main functions of testes are sperm production and androgen secretion in testicular befitting microenvironment. Excessive level of the reactive oxygen species (ROS) from metabolism and cellular events can lead to oxidative stress (OS) and ferroptosis, which injure the functions of mitochondria and endoplasmic reticulum (ER) of ...
Shuning Yuan   +10 more
wiley   +1 more source

Determinacy Through Intertemporal Capital Adjustment Costs [PDF]

open access: yes
It is well known that if mild sector–specific externalities are considered, then the steady state of the standard two-sector real business cycle model can become locally indeterminate and endogenous business cycles can arise.
Akos Valentinyi, Berthold Herrendorf
core  

LAT1/SLC7A5‐mediated amino acid uptake is regulated by redox signals triggered by formyl‐peptide receptor 2

open access: yesThe FEBS Journal, EarlyView.
FPR2 activation mediates NOX‐dependent LAT1 expression and, in turn, promotes mTORC1 signaling. Upon stimulation with WKYMVm, the FPR2‐NOX2‐ROS axis upregulates LAT1 via increased c‐Myc phosphorylation and decreased miR‐126. Additionally, it promotes CD98 translocation to the plasma membrane.
Myrhiam Cassese   +5 more
wiley   +1 more source

Neoclassical Growth Model with Externalities [PDF]

open access: yes
This paper explores the local stability properties of the steady state in the twosector neoclassical growth model with sector–specific externalities. We show analytically that capital adjustment costs of any size preclude local indeterminacy nearby the ...
Akos Valentinyi, Berthold Herrendorf
core  

Modeling and Optimization of Complex Building Energy Systems with Deep Neural Networks

open access: yes, 2017
Modern buildings encompass complex dynamics of multiple electrical, mechanical, and control systems. One of the biggest hurdles in applying conventional model-based optimization and control methods to building energy management is the huge cost and ...
Chen, Yize, Shi, Yuanyuan, Zhang, Baosen
core   +1 more source

Computational Investigation on the Combined Effect of Applied Strain and Pore Configuration on Strain Concentrators in Additively Manufactured Metals

open access: yesFatigue &Fracture of Engineering Materials &Structures, EarlyView.
ABSTRACT Metal additive manufacturing (AM) provides a pathway for creating highly optimized components that would be difficult to produce using traditional manufacturing methods. However, regardless of printing parameters or postprocessing, porosity remains a prevalent challenge in AM components because strain concentrates in the vicinity of the pore ...
Erick Adan Ramirez   +3 more
wiley   +1 more source

FY05 Xradia 3D (mu)XCT System Accomplishments

open access: yes, 2005
The Xradia 3D {mu}XCT system was delivered to LLNL on April 5, 2005. The system became operational the week of April 11, 2005. The Xradia 3D {mu}XCT system has been extensively used to scan several high-energy density physics (see Table 1) and other programmatic (NIF, E&E and DNT) materials, components and full assemblies. In this summary we only focus
openaire   +2 more sources

Influence of spectra sewing on XCT measurement

open access: yes
The paper presents an analysis of the possible spectra manipulation and its consequence for the specific application of XCT. The focus was on the modification of the registered spectra dominantly by the sewing/stitching method. A model spectrum was created to analyse the possible behaviour of the spectral components when specifically arranged.
Arikkat, A. J.   +3 more
openaire   +2 more sources

xCT as a Predictor for Survival in a Population‐Based Cohort of Head and Neck Squamous Cell Carcinoma

open access: yesCancer Medicine
Background xCT, also known as SLC7A11 (solute carrier Family 7 Member 11), is a cystine/glutamate antiporter protein that mediates regulated cell death and antioxidant defense.
Linda Nissi   +10 more
doaj   +1 more source

Effects of amoxicillin and Augmentin on cystine-glutamate exchanger and glutamate transporter 1 isoforms as well as ethanol intake in alcohol-preferring rats

open access: yesFrontiers in Neuroscience, 2016
Alcohol dependence is associated with alteration of glutamate transport and glutamate neurotransmission. Glutamate transporter 1 (GLT-1) is a major transporter that regulates the majority of extracellular glutamate concentration, which is also regulated
Alqassem Y Hakami   +2 more
doaj   +1 more source

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