Results 191 to 200 of about 26,824 (211)

SLC7A11/xCT Prevents Cardiac Hypertrophy by Inhibiting Ferroptosis

Cardiovascular Drugs and Therapy, 2021
Systemic hypertension may induce adverse hypertrophy of the left cardiac ventricle. Pathological cardiac hypertrophy is a common cause of heart failure. We investigated the significance of ferroptosis repressor xCT in hypertrophic cardiomyopathy.xCT expression in angiotensin II (Ang II)-treated mouse hearts and rat cardiomyocytes was determined using ...
Xiyu, Zhang, Cuiting, Zheng, Zhenqiang, Gao, Hongyu, Chen, Kai, Li, Lingling, Wang, Yuanyuan, Zheng, Chunjia, Li, Hongjia, Zhang, Ming, Gong, Hongbing, Zhang, Yan, Meng   +11 more
openaire   +2 more sources

xCT/SLC7A11 antiporter function inhibits HIV-1 infection

Virology, 2021
Human macrophages are protected by intrinsic antiviral defenses that provide moderate protection against HIV-1 infection. Macrophages that do become infected can serve as long-lived reservoirs, to disseminate HIV-1 to CD4+ T cells. Infection of macrophages with HIV-1 and HIV-2 is inhibited by constitutive mobilization of antioxidant response master ...
Jesse Rabinowitz, Hamayun J. Sharifi, Hunter Martin, Anthony Marchese, Michael Robek, Binshan Shi, Alexander A. Mongin, Carlos M.C. de Noronha   +7 more
openaire   +2 more sources

Least-squares and maximum-likelihood in XCT

Developments in X-Ray Tomography XIII, 2021
Statistical reconstruction methods in X-ray Computed Tomography (XCT) are well-regarded for their ability to produce more accurate and artefact-free reconstructed volumes, in the presence of measurement noise. Maximum-likelihood methods are particularly salient and have been shown to result in superior reconstruction quality, compared with methods that
Murdock Grewar, Glenn Myers, Andrew Kingston   +2 more
openaire   +1 more source

Precision of the XCT 3000 and Comparison of Densitometric Measurements in Distal Radius Scans Between XCT 3000 and XCT 2000 Peripheral Quantitative Computed Tomography Scanners

Journal of Clinical Densitometry, 2008
Researchers conducting longitudinal studies face challenges as technology evolves and data collection equipment is upgraded from older to newer models. In this study, we report precision error and associations from correlation, regression equations, and Bland-Altman plots that compare results of distal radius images from the XCT 2000 and XCT 3000 ...
Cory, Koenig, Howard, Wey, Teresa, Binkley   +2 more
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Bone and Muscle Parameters of the Tibia: Agreement Between the XCT 2000 and XCT 3000 Instruments

Journal of Clinical Densitometry, 2009
Peripheral quantitative computed tomography is a valuable tool to assess bone in children across growth, with long-term studies capturing nuances missed in cross-sectional studies. As children grow, a change from XCT 2000 to a XCT 3000 may be required to accommodate the increasing size of the lower limbs. We examined the precision and agreement between
Burrows, Melonie, Cooper, David M. L., Liu, Danmei, McKay, Heather A.   +3 more
openaire   +3 more sources

Decreased reproductive performance in xCT-knockout male mice

Free Radical Research, 2017
Sulphoxidation occurs in protamines that are enriched in cysteine and supplies chromatin for packaging. The extracellular fluid contains higher levels of oxidised cysteine (cystine), and some cells utilise system xc-, a cystine transporter in which xCT is the main protein component, to fulfil the need for cysteine. We hypothesised that system xc- might
Shinji, Hamashima, Takujiro, Homma, Sho, Kobayashi, Naoki, Ishii, Toshihiro, Kurahashi, Ren, Watanabe, Naoko, Kimura, Hideyo, Sato, Junichi, Fujii   +8 more
openaire   +2 more sources

Meso-scale XCT-based modeling of ordinary concrete

Construction and Building Materials, 2021
Abstract The increasing attention to numerical issues related to material modeling is still a strong incentive to develop sound mechanical models that can explain material behavior up to failure. A procedure to handle a robust geometric meso-scale reconstruction of concrete materials is here proposed, based on X-ray Computed Tomography (CT-scan or X ...
Mazzucco Gianluca, Pomaro Beatrice, Xotta Giovanna, Garbin Enrico, Maiorana Carmelo, De Marchi Nico, Concheri Gianmaria   +6 more
openaire   +3 more sources

XCT - Röntgen-Computertomographie

2017
Bei dieser Technik wird das zwischen Rontgenrohre und Flachendetektor angeordnete Objekt in definierten Winkelschritten gedreht und je ein zweidimensionales Radiographiebild detektorseitig registriert. In der Detektorebene wird somit die Absorption der Rontgenstrahlen langs einer Vielzahl von Geraden von der Rontgenquelle zum Detektor in einer Ebene ...
Jürgen Bauch, Rüdiger Rosenkranz
openaire   +1 more source

Defect prediction dataset (Thermography & XCT)

2023
Thermogram feature data and x-ray computed tomography (XCT) data from 316L stainless steel specimen manufactured by PBF-LB/M. The experimental setup and feature extractionis described in [https://doi.org/10.1117/12.2587913]. Both datasets were registered according to [https://doi.org/10.3390/met12060947].
openaire   +1 more source

JNK activation mediates the apoptosis of xCT-deficient cells

Biochemical and Biophysical Research Communications, 2008
System X(c)(-) is an anionic amino acid transport system highly specific for cystine and glutamate. The underlying mechanism of cell death of cultured cells from the subtle gray (sut) mouse which contains an xCT null mutation remains elucidated. Our results show that the death of sut cells is likely caused by apoptosis mediated by c-Jun N-terminal ...
Hai-Xuan, Qiao, Chan-Juan, Hao, Yan, Li, Xin, He, Ri-Sheng, Chen, Jie, Cui, Zhi-Heng, Xu, Wei, Li   +7 more
openaire   +2 more sources