Characterization of heterogeneity and spatial distribution of phases in complex solid dispersions by thermal analysis by structural characterization and X-ray micro computed tomography [PDF]
Purpose: This study investigated the effect of drug-excipient miscibility on the heterogeneity and spatial distribution of phase separation in pharmaceutical solid dispersions at a micron-scale using two novel and complementary characterization ...
Alhijjaj, Muqdad +5 more
core +1 more source
Effect of horse sex status on British Eventing competition performance: an observational study between 1998 and 2016 [PDF]
To test the hypothesis that gender affects horse scores in eventing competition, data on the scores and points awarded to 681 horses was collected from the British Eventing website.
Fouladi-Nashta, A A +2 more
core +2 more sources
Yunhan Zhang,1,* Meihui Xia,2,* Zizhen Zhou,3 Xiaoqing Hu,1 Jiabin Wang,1 Meiyu Zhang,3 Yi Li,4 Liankun Sun,1 Fangfang Chen,4,5 Huimei Yu1,6 1Key Laboratory of Pathobiology, Ministry of Education, Department of Pathophysiology, College of Basic Medical ...
Zhang Y +9 more
doaj
Applications of X-ray computed tomography in textile field
Traditional optical imaging technique used as an analysis method for microstructure can only observe surface and can't achieve 3D characterization of the material interior, which greatly limits its application in textile field.
GUO Weina +3 more
doaj +1 more source
Augmented Cystine–Glutamate Exchange by Pituitary Adenylate Cyclase-activating Polypeptide Signaling via the VPAC1 Receptor [PDF]
In the central nervous system, cystine import in exchange for glutamate through system xc- is critical for the production of the antioxidant glutathione by astrocytes, as well as the maintenance of extracellular glutamate. Therefore, regulation of system
Arimura +74 more
core +2 more sources
Novel mouse model for evaluating in vivo efficacy of xCT inhibitor
xCT, a well-known cystine transporter, is reported to be involved in the proliferation of various cells, such as cancer cells, immune cells, and fibroblasts. xCT inhibitor is expected to be a promising drug for cancer or immune diseases.
Ryosuke Yoshioka +7 more
doaj +1 more source
AbstractChondrules are microscopic, recrystallized melt droplets found in chondritic meteorites. High‐resolution isotope analyses of minor elements require large enough element quantities which are obtained by dissolving entire chondrules. This work emphasizes the importance of X‐ray computed tomography (XCT) to detect features that can significantly ...
Noah Jäggi +4 more
openaire +3 more sources
xCT forms part of the xc− cysteine-glutamate antiporter which inhibits antimicrobial inflammatory immune functions and thus increases susceptibility to tuberculosis (TB).
Wenfei Wang +10 more
doaj +1 more source
Optical and XCT Measurement of Additively Manufactured Surfaces
This paper illustrates the comparative results of measuring the surface texture of additive manufacturing parts using optical techniques (Alicona G4) and X-ray Computed Tomography (Nikon XTH225). The results of optical and XCT measurements are analysed respectively, per the surface texture parameters of ISO 25178-2.
openaire +3 more sources
Structure‐Activity‐Relationship‐Aided Design and Synthesis of xCT Antiporter Inhibitors [PDF]
AbstractThe xCT antiporter is a cell membrane protein involved in active counter‐transportation of glutamate (outflux) with cystine (influx) over the human cell membrane. This feature makes the xCT antiporter a crucial element of the biosynthesis of the vital free radical scavenger glutathione.
Davide Cirillo +3 more
openaire +4 more sources

