Results 81 to 90 of about 26,824 (211)
xCT inhibition sensitizes tumors to γ-radiation via glutathione reduction [PDF]
Oncotarget, 2018 About 3 million US cancer patients and 1.7 million EU cancer patients received multiple doses of radiation therapy (RT) in 2012, with treatment duration limited by normal adjacent tissue damage. Tumor-specific sensitization could allow treatment with lower radiation doses, reducing normal tissue damage.
Timmerman, Luika A +4 more
openaire +5 more sources
Journal of Inflammation, 2007 Background Cystine/glutamate transporter, system xc-, contributes to the maintenance of intracellular glutathione levels and the redox balance in the extracellular space.
Bannai Shiro +3 more
doaj +1 more source
Pancreatic acinar cell fate relies on system xC - to prevent ferroptosis during stress
Cell Death and Disease, 2023 Acinar cell dedifferentiation is one of the most notable features of acute and chronic pancreatitis. It can also be the initial step that facilitates pancreatic cancer development.
Zhaolong Pan +10 more
doaj +1 more source
GPX4 Inhibitor Resistance and Metastatic Features in Triple‐Negative Breast Cancer
Advanced Science, EarlyView.This study establishes breast cancer cell lines that are resistant to glutathione peroxidase 4 inhibitors (GPX4i) in vitro and investigates the metastatic capacity of the GPX4i‐resistant versus parental lines in vivo. GPX4i‐resistant cells survive upon intravenous injection, but lose capacity to spontaneously metastasize.
Marie Sabatier +16 more
wiley +1 more source
Anti-adiabatic limit of the exchange-correlation kernels of an inhomogeneous electron gas [PDF]
, 2010 We express the high-frequency (anti-adiabatic) limit of the exchange-correlation kernels of an inhomogeneous electron gas in terms of the following equilibrium properties: the ground-state density, the kinetic stress tensor, the pair-correlation function,
A. Holas +6 more
core +3 more sources
Advanced Science, EarlyView.ABSTRACT The lithium plating reaction in graphite electrodes acts as a root cause for the accelerated degradation and the internal short circuits in lithium‐ion batteries. Here, an electrochemical model based on multi‐scale microstructural images was established to identify lithium plating‐stripping processes, thereby supporting the predictive outcomes
Heng Huang +9 more
wiley +1 more source
Sulfide‐Based Electrolytes for All‐Solid‐State Sodium Batteries
Advanced Energy Materials, EarlyView.This review covers the structural features and synthesis strategies of sulfide‐based solid electrolytes, as well as critical challenges related to conductivity, interfacial and moisture stability, and scaling‐up for practical application in Sodium‐based All Solid‐State Batteries.
Han Yang +6 more
wiley +1 more source
Advanced Intelligent Systems, EarlyView.Feature from recent image foundation models (DINOv2) are useful for vision tasks (segmentation, object localization) with little or no human input. Once upsampled, they can be used for weakly supervised micrograph segmentation, achieving strong results when compared to classical features (blurs, edge detection) across a range of material systems.
Ronan Docherty +2 more
wiley +1 more source
xCT expression modulates cisplatin resistance in Tca8113 tongue carcinoma cells
Oncology Letters, 2016 Tongue squamous cell carcinoma (TSCC), which is a subtype of head and neck cancer, is the most common type of oral cancer. Due to its high recurrence rate and chemoresistance, the average survival rate for patients with TSCC remains unsatisfactory.
Peng, Zhang +5 more
openaire +3 more sources
Applicability and Utility of the Astromaterials X-Ray Computed Tomography Laboratory at Johnson Space Center [PDF]
The Astromaterials Acquisition and Curation Office at NASAs Johnson Space Center is responsible for curating all of NASAs astromaterial sample collections (i.e.
Eckley, S. A. +5 more
core +1 more source