Results 151 to 160 of about 149,321 (334)

A Review of the Occurrence of Metals and Xenobiotics in European Hedgehogs (Erinaceus europaeus)

open access: yesAnimals
Monitoring data from several European countries indicate that European hedgehog (Erinaceus europaeus) populations are declining, and research exploring the causes of the decline, including exposure to potentially harmful xenobiotics and metals, may ...
Sophie Lund Rasmussen   +4 more
doaj   +1 more source

Investigation of effects of two environmental heavy metals in a combined exposure model on the nervous system in rats [PDF]

open access: yes, 2012
In the present study, the interaction of inhalational and oral exposure to manganese and lead was investigated. Young adult male Wistar rats (2 x 10 per group) were treated orally with MnCl2 (15 and 60 mg/kg b.w.) or Pb acetate (80 and 320 mg/kg) for 3 ...
Horváth, Edina   +3 more
core  

Functional Bread From Bambara Groundnut and Orange Peel Attenuates Hyperglycemia and Oxidative Stress in a High‐Fat Diet/Streptozotocin‐Induced Type 2 Diabetes Rat Model

open access: yesFood Chemistry International, EarlyView.
This study evaluated Bambara groundnut–wheat composite bread fortified with orange peel in diabetic rats. Diets significantly lowered blood glucose, inhibited α‐glucosidase and α‐amylase, and boosted antioxidant enzymes compared to controls. Results emphasize BG‐based functional foods' potential to help manage type 2 diabetes through regulation of ...
S. O. Oguntuase   +3 more
wiley   +1 more source

Do Microplastics in Soil Influence the Bioavailability of Sulfamethoxazole to Plants?

open access: yesPlants
The presence of pharmaceuticals and MPs in soil raises concern due to their potential impact on plant health and ecosystem stability. This study investigates the impact of MPs on the bioavailability and phytotoxicity of sulfamethoxazole (SMX) using ...
Anna Parus   +3 more
doaj   +1 more source

Noninvasive Disease Diagnostics: The Swiss Contribution Highlights to Breath Analysis Research

open access: yesHelvetica Chimica Acta, EarlyView.
Breath analysis networks across Switzerland linking health monitoring, clinical applications, population studies, and data‐driven public health decisions. ABSTRACT To celebrate the 125th anniversary of the Swiss Chemical Society, we present a review and perspective to highlight the recent research in breath analysis that has been conducted in ...
Stefan James Swift   +6 more
wiley   +1 more source

Convergent evolution of metabolic functions: Evidence from the gut microbiomes of humans and dogs

open access: yesiMetaOmics, EarlyView.
Dogs have undergone convergent evolution in their genome with humans in long‐term co‐living. Studies have shown that the gut microbiomes of dogs exhibit greater similarity to those of humans compared to mice and pigs. In our study, we first compared the gut microbiomes of macaques, three dog groups, and two wolf groups to those in humans.
Xiaoyang Wang   +10 more
wiley   +1 more source

Nano‐plastics disrupt systemic metabolism by remodeling the bile acid–microbiota axis and driving hepatic–intestinal dysfunction

open access: yesiMeta, EarlyView.
The pervasiveness of microplastic pollution poses a growing health risk, yet its long‐term metabolic consequences remain poorly defined. Here, we exposed mice to polyethylene terephthalate nanoparticle (NP) and combined histopathology, biochemistry, metabolomics, and metagenomics to resolve their interactions.
Yi Zhang   +11 more
wiley   +1 more source

Impact of organic pollutants on phenotype and gene expression in human breast cancer cells

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Human exposure to industrial chemical compounds is widespread and, although often beneficial, prolonged contact may contribute to disease development, including cancer. While many studies have shown organic pollutants (OP) are cytotoxic, few have explored how long‐term exposure alters cell phenotype.
Camila Confortin   +7 more
wiley   +1 more source

Evaluation of Acephate Metabolites Generated by Zebrafish (Danio rerio) Using LC–HRMS and Metabolomics Approach

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Acephate is an organophosphate insecticide widely used. This pesticide can be metabolized into methamidophos, a molecule highly toxic. Both have demonstrated the ability to promote serious toxic effects on nontarget organisms and have been identified in surface waters around the world. Therefore, it is important to understand their behavior in
Mariana Laiz Silva de Lima   +3 more
wiley   +1 more source

Chronic Low‐Dose Unsymmetrical Dimethylhydrazine Exposure in Rats: Multiorgan Mechanisms and Biomarker Identification

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Unsymmetrical dimethylhydrazine (UDMH), a highly toxic rocket propellant with known multiorgan effects, requires urgent characterization of its chronic low‐dose toxicity. Using an integrated approach including exploratory transcriptomics (n = 3/group) and metabolomic (n = 4/group) approaches in male Sprague–Dawley rats exposed to high‐dose ...
Fuzhou Liu   +6 more
wiley   +1 more source

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