Results 211 to 220 of about 149,321 (334)

Tryptophan‐Derived Microbial Metabolite Indole‐3‐Acetic Acid Ameliorates Periodontitis Through AhR/CYP1A1‐Mediated Macrophage Polarisation

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aim To investigate the association between tryptophan‐derived microbial metabolites and periodontitis, and to assess whether the differential tryptophan metabolite indole‐3‐acetic acid (IAA) could ameliorate periodontitis and elucidate its potential mechanism.
Shuyu Cheng, Shiyuan Song, Wen Zhang, Dan Qiao, Min Wang, Zhifeng Wang, Jiajie Pu, Wenrong Yang, Fuhua Yan, Yangheng Zhang   +9 more
wiley   +1 more source

Genetic architecture of resistance to plant secondary metabolites in Photorhabdus entomopathogenic bacteria. [PDF]

BMC Genomics
Boss A, Toepfer S, Erb M, Machado RAR.
europepmc   +1 more source

Therapeutic advances in pruritus as a model of personalized medicine

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Recent advances in itch biology reveal that chronic pruritus arises from distinct neuroimmune pathways driven by cytokines, JAK, BTK and GPCRs. Targeted biologics and small molecule inhibitors such as dupilumab, nemolizumab, remibrutinib and JAK inhibitors precisely modulate these pathways, leading to a new era of personalized therapeutics in pruritus.
Kelsey Auyeung, Ramsey Kubofcik, Brian S. Kim   +2 more
wiley   +1 more source

Editorial: Xenosensors as the targets of endocrine-disrupting chemicals. [PDF]

Front Endocrinol (Lausanne)
Ghassemi-Barghi N, Khan F, Bayrami Z.
europepmc   +1 more source

AlkaPlorer: A database‐driven explorer for natural alkaloids and derivatives

Journal of Integrative Plant Biology, EarlyView.
The alkaloid database AlkaPlorer integrates over 130,000 compounds across 12,250 species. By linking chemical structures with biological and evolutionary data, it reveals how these molecules evolve and function. This platform serves as a vital resource for AI‐driven discovery in plant metabolism and modern drug development. ABSTRACT Alkaloids, renowned
Jiahao Li, Tao Zeng, Hongquan Xu, Xu Kang, Minghui Liang, Ruibo Wu   +5 more
wiley   +1 more source

Urinary Metabolomics as a Window into Occupational Exposure: The Case of Foundry Workers. [PDF]

J Xenobiot
De Rosa M, Canepari S, Tranfo G, Giampaoli O, Patriarca A, Smolinska A, Marini F, Massimi L, Sciubba F, Spagnoli M.   +9 more
europepmc   +1 more source

Xenobiotics: Interaction with the Intestinal Microflora.

ILAR journal, 2015
Kun Lu, R. Mahbub, J. Fox
semanticscholar   +1 more source

Erythrocyte ‘Feierzeit’ reaction: Novel filamentous and vesicular response to n‐butyl acetate

Journal of Microscopy, EarlyView.
Abstract Human erythrocytes (red blood cells; RBCs) undergo spontaneous disassembly after several hours of exposure to n‐butyl acetate (nBA). Images of the morphological changes were captured in time‐lapse sequences using differential interference contrast (DIC) light microscopy.
Philip W. Kuchel
wiley   +1 more source

Xenobiotic resistance in mosquito eggs: current understanding and data gaps. [PDF]

PeerJ
Turaga U, Peper ST, Garcia CJ, Presley SM.   +3 more
europepmc   +1 more source

Impact of Electronic Nicotine Delivery Systems on Oral Mucosa: A Cytopathological and Molecular Study

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Background The packaging and marketing of electronic cigarettes (e‐cigs) often target younger demographics. This study aimed to evaluate gene expression in e‐cig users through exfoliative cytology. Methods Samples were collected from 17 e‐cig users and 10 nonsmokers as controls.
Alba Pérez‐Jardón, Bruna Fernandes do Carmo Carvalho, Cintia Micaela Chamorro‐Petronacci, Maria Dolores Reboiras‐López, Natalia de Carvalho Faria, Renata Falchete do Prado, Mónica Ghislaine Oliveira Alves, Fábio França Vieira e Silva, Maria‐Elena Padín‐Iruegas, Mario Pérez‐Sayáns, Janete Dias Almeida   +10 more
wiley   +1 more source