Results 41 to 50 of about 54,719 (182)
Advanced Healthcare Materials, EarlyView.This study introduces a modular microfluidic platform that connects liver cells with live microbes to mimic key aspects of the gut–liver interaction in steatosis. Using this system, both microbial metabolites and live bacteria significantly reduced fat accumulation in liver cells, but live microbes triggered inflammation and broader metabolic changes ...
Hsih‐Yin Tan +7 more
wiley +1 more source
Monitoring of selected essential elements and contaminants at sheep and cow farms in Eastern Slovakia [PDF]
Journal of Central European Agriculture, 2016 The aim of this study was to determinate the actual contamination of selected area of Slovakia, in view of its environmental character referred both to the suitability or unsuitability of the use of milk from this area, to other food processing.
Martina TUNEGOVÁ +2 more
doaj +1 more source
Advanced Science, EarlyView.Lactate in cervical cancer induces HNRNPU K181 lactylation, opposed by NAA50‐mediated acetylation and suppressed by Pazopanib. This lactylation enhances HNRNPU binding to PHGDH pre‐mRNA exon 1, maintaining exon 1‐containing transcripts and mRNA stability, thereby activating serine metabolism.
Chang Zhang +6 more
wiley +1 more source
White Rot Fungi as Tools for the Bioremediation of Xenobiotics: A Review
Journal of FungiIndustrial development has enhanced the release into the environment of large quantities of chemical compounds with high toxicity and limited prospects of degradation.
Giselle Torres-Farradá +4 more
doaj +1 more source
Advanced Science, EarlyView.Comparative genomics of Gondwana‐diverged Pila and Pomacea reveals parallel evolution of aerial oviposition. Convergent chromosomal rearrangements reshape regulatory landscapes within topologically associating domains. Lineage‐specific gene family expansions and viral‐derived perivitelline proteins (PV1) underpin desiccation resistance.
Yufei Zhou +10 more
wiley +1 more source
Relevance of Carcinogen-Induced Preclinical Cancer Models
Journal of XenobioticsChemical agents can cause cancer in animals by damaging their DNA, mutating their genes, and modifying their epigenetic signatures. Carcinogen-induced preclinical cancer models are useful for understanding carcinogen-induced human cancers, as they can ...
Raj N. Sewduth, Konstantina Georgelou
doaj +1 more source
The role of invariant surface glycoprotein 75 in xenobiotic acquisition by African trypanosomes
Microbial Cell, 2023 The surface proteins of parasitic protozoa mediate functions essential to survival within a host, including nutrient accumulation, environmental sensing and immune evasion.
Alexandr Makarov +7 more
doaj +1 more source
Advanced Science, EarlyView.An optimized ex vivo human liver slice culture system preserves tissue architecture, hepatocyte function, and immune‐stromal complexity for at least five days. By refining slice thickness, oxygenation, air‐liquid interface, and extracellular matrix support, the platform enables human‐relevant hepatotoxicity testing and mechanistic studies, offering a ...
Huiche Feng +17 more
wiley +1 more source
Making Sweat Measurable: Induction, Sampling, and Refreshment in Wearable Biofluid Sensing
Advanced Science, EarlyView.Wearable sweat sensing relies not only on chemical detection but also on controlled biofluid management. This Review integrates sweat physiology, induction strategies, and microfluidic sampling architectures, demonstrating how flux, transport, and refreshment shape measurement reliability.
Soyoung Shin, Wei Gao
wiley +1 more source
Activation of PXR by Alpinetin Contributes to Abrogate Chemically Induced Inflammatory Bowel Disease
Frontiers in Pharmacology, 2020 Alpinetin is a naturally occurring flavonoid from the ginger plants. We previously reported the identification of alpinetin as a ligand of human pregnane X receptor (hPXR).
Zhilun Yu +8 more
doaj +1 more source