Results 31 to 40 of about 77,053 (291)
Frontiers in Cellular Neuroscience, 2018 The main olfactory epithelium (MOE) functions to detect odor molecules, provide an epithelial surface barrier, and remove xenobiotics from inhaled air.
Ziying Fu +3 more
doaj +1 more source
Transcriptomic Profiling of SLC and ABC Transporters in the Human Term Placenta. [PDF]
Clin Pharmacol TherSolute carriers (SLC) and ATP‐binding cassette (ABC) transporters are essential for placental solute exchange and fetal protection, yet their transcriptomic profiles in the human placenta remain poorly characterized. Although fetal sex influences placental development and function, its impact on transporter expression is unclear.
Jung EM +12 more
europepmc +2 more sources
The steroid and xenobiotic receptor (SXR), beyond xenobiotic metabolism [PDF]
Nuclear Receptor Signaling, 2009 The steroid and xenobiotic receptor (SXR) (also known as pregnane X receptor or PXR) is a nuclear hormone receptor activated by a diverse array of endogenous hormones, dietary steroids, pharmaceutical agents, and xenobiotic compounds. SXR has an enlarged, flexible, hydrophobic ligand binding domain (LBD) which is remarkably divergent across mammalian ...
Zhou, Changcheng +2 more
openaire +2 more sources
Archives of Plastic Surgery, 2021 Background The result of illicit polymer injection is chronic inflammation with foreign-body granuloma (FBG) formation. Treatment can be divided into medical and surgical. Some patients develop severe complications with need surgical treatment.
Javier Lopez-Mendoza +3 more
doaj +1 more source
Lessons From Insect Fungiculture: From Microbial Ecology to Plastics Degradation
Frontiers in Microbiology, 2022 Anthropogenic activities have extensively transformed the biosphere by extracting and disposing of resources, crossing boundaries of planetary threat while causing a global crisis of waste overload. Despite fundamental differences regarding structure and
Mariana O. Barcoto +3 more
doaj +1 more source
Frontiers in Bioengineering and Biotechnology, 2021 Global environmental contamination with a complex mixture of xenobiotics has become a major environmental issue worldwide. Many xenobiotic compounds severely impact the environment due to their high toxicity, prolonged persistence, and limited ...
Sandhya Mishra +11 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Study of interaction of xenobiotics with macrophytes in experimental aquatic ecosystems
RUDN Journal of Ecology and Life Safety, 2021 Phytotoxicity of three types of organic xenobiotics (ethyl acetate, butanol-1, tetrachloromethane) was evaluated when three macrophyte species Ceratophyllum demersum , Elodea canadensis , Chara fragilis were exposed.
Vladislav A. Poklonov +4 more
doaj +1 more source
Glucosylation of xenobiotics in maize, soybean and arabidopsis thaliana [PDF]
, 2004 Many natural products and xenobiotics become glucosylated in the course of their metabolism in plants. This reaction is catalysed by type 1 UDP-glucose dependent glucosyltransferases (GTs), a super-family of enzymes which differ in their substrate ...
Loutre, Caroline
core
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source