Results 171 to 180 of about 121,926 (279)

Xenbase: 25 years of integrating molecular and biomedical data from Xenopus. [PDF]

open access: yesGenetics
Chu S   +18 more
europepmc   +1 more source

Pitfalls and missing links in current understanding of 4D genomes

open access: yesQuantitative Biology, Volume 14, Issue 2, June 2026.
Abstract The spatial and temporal organization of the genome—collectively termed the 4D genome—is pivotal for regulating gene expression, maintaining genome stability, and guiding development. The convergence of chromosome conformation capture technologies, super‐resolution microscopy, and single‐cell epigenomics has transformed our understanding of ...
Michael Q. Zhang
wiley   +1 more source

A homozygous human WNT11 variant is associated with laterality, heart and renal defects

open access: yesDisease Models & Mechanisms
Henrike Berns   +6 more
doaj   +1 more source

Cryo‐EM structure of ALC1 in an open conformation bound to a PARylated nucleosome

open access: yesActa Crystallographica Section D, Volume 82, Issue 6, Page 683-699, June 2026.
Reanalysis of a publicly available cryo‐EM dataset identifies a new conformation of the oncogenic chromatin remodeler ALC1/CHD1L bound to a PARylated nucleosome. This new structure reveals the position of the macro domain in the complex, and may help to understand the large conformational change leading to the activation of ALC1.Nucleosomes are the ...
Hannah R. Bridges   +3 more
wiley   +1 more source

Roles of ER Membrane Protein Complex in Protein Biogenesis and Quality Control in the Lung and Beyond

open access: yesCell Proliferation, Volume 59, Issue 6, June 2026.
The endoplasmic reticulum membrane protein complex (EMC) is an evolutionarily conserved, multi‐subunit transmembrane protein complex crucial to membrane protein biogenesis and cellular protein quality control. This review systematically examines the structure, functions and disease‐associated regulatory mechanisms of EMC across multiple organ systems ...
Yan Qiao   +6 more
wiley   +1 more source

Prickle and Ror modulate Dishevelled-Vangl interaction to regulate non-canonical Wnt signaling during convergent extension in <i>Xenopus</i>. [PDF]

open access: yesElife
Seo HS   +11 more
europepmc   +1 more source

NPF2 is involved in intracellular pH regulation and ion balance in the diatom Phaeodactylum tricornutum

open access: yesNew Phytologist, Volume 250, Issue 6, Page 3885-3899, June 2026.
Summary Cellular ion and pH homeostasis are crucial factors affecting and regulating metabolic reactions, protein stability, signalling and transport mechanisms. To balance intracellular ion concentrations, organisms need to constantly sense and respond to both the extracellular environment and cell compartments' requests.
Anna Santin   +15 more
wiley   +1 more source

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