Xenbase: 25 years of integrating molecular and biomedical data from Xenopus. [PDF]
Chu S +18 more
europepmc +1 more source
Pitfalls and missing links in current understanding of 4D genomes
Abstract The spatial and temporal organization of the genome—collectively termed the 4D genome—is pivotal for regulating gene expression, maintaining genome stability, and guiding development. The convergence of chromosome conformation capture technologies, super‐resolution microscopy, and single‐cell epigenomics has transformed our understanding of ...
Michael Q. Zhang
wiley +1 more source
A homozygous human WNT11 variant is associated with laterality, heart and renal defects
Henrike Berns +6 more
doaj +1 more source
Bilateral equalization of synaptic output in olfactory glomeruli of <i>Xenopus</i> tadpoles. [PDF]
Casas M, Terni B, Llobet A.
europepmc +1 more source
Cryo‐EM structure of ALC1 in an open conformation bound to a PARylated nucleosome
Reanalysis of a publicly available cryo‐EM dataset identifies a new conformation of the oncogenic chromatin remodeler ALC1/CHD1L bound to a PARylated nucleosome. This new structure reveals the position of the macro domain in the complex, and may help to understand the large conformational change leading to the activation of ALC1.Nucleosomes are the ...
Hannah R. Bridges +3 more
wiley +1 more source
Simultaneous Whole-Cell Recording and Calcium Imaging Does Not Reveal Electrically Coupled Neurons in <i>Xenopus</i> Tadpoles. [PDF]
Xu-Ying B, Zwart MF, Li WC.
europepmc +1 more source
The endoplasmic reticulum membrane protein complex (EMC) is an evolutionarily conserved, multi‐subunit transmembrane protein complex crucial to membrane protein biogenesis and cellular protein quality control. This review systematically examines the structure, functions and disease‐associated regulatory mechanisms of EMC across multiple organ systems ...
Yan Qiao +6 more
wiley +1 more source
Prickle and Ror modulate Dishevelled-Vangl interaction to regulate non-canonical Wnt signaling during convergent extension in <i>Xenopus</i>. [PDF]
Seo HS +11 more
europepmc +1 more source
Summary Cellular ion and pH homeostasis are crucial factors affecting and regulating metabolic reactions, protein stability, signalling and transport mechanisms. To balance intracellular ion concentrations, organisms need to constantly sense and respond to both the extracellular environment and cell compartments' requests.
Anna Santin +15 more
wiley +1 more source
A FKBP (FK506 Binding protein) enhances BMP signaling during Xenopus dorso-ventral patterning
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한진관, 여인철
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