Results 31 to 40 of about 137,221 (140)

Xenopus laevis Oocytes

, 2003
Xenopus oocytes are a versatile expression system particularly suited for membrane transporters and channels. Oocytes have little background activity and therefore offer a very high signal-to-noise ratio for transporter and channel characterization. This chapter provides an overview of the basic methods used for the analysis of membrane transporters in
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An ontology for Xenopus anatomy and development [PDF]

BMC Developmental Biology, 2008
Abstract Background The frogs Xenopus laevis and Xenopus (Silurana) tropicalis are model systems that have produced a wealth of genetic, genomic, and developmental information. Xenbase is a model organism database that provides centralized access to this information, including gene function data from high-throughput ...
Peter D. Vize, Erik Segerdell, Jeff B. Bowes, Nicolas Pollet, Nicolas Pollet   +4 more
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TALEN-mediated apc mutation in Xenopus tropicalis phenocopies familial adenomatous polyposis [PDF]

, 2015
Truncating mutations in the tumor suppressor gene adenomatous polyposis coli (APC) are the initiating step in the vast majority of sporadic colorectal cancers, and they underlie familial adenomatous polyposis (FAP) syndromes.
Creytens, David, Geurs, Sarah, Naert, Thomas, Sanders, Ellen, Tran Thi, Hong, Van Imschoot, Griet, Van Nieuwenhuysen, Tom, Van Roy, Frans, Vleminckx, Kris   +8 more
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The Immunoglobulins of Cold-Blooded Vertebrates [PDF]

, 2014
Peer reviewedPublisher ...
Chen, Clem, Cone, Cooper, Crouch, Deza, Grey, Hadji-Azimi, Hsu, Kokubu, Leslie, Magor, Malecek, Mansikka, Patel, Schaerlinger, Schaerlinger, Small, Steiner, Turchin, Wilson, Wu, Zapata   +22 more
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Primitive roles for inhibitory interneurons in developing frog spinal cord [PDF]

, 2004
Understanding the neuronal networks in the mammal spinal cord is hampered by the diversity of neurons and their connections. The simpler networks in developing lower vertebrates may offer insights into basic organization.
Higashijima, S-I, Li, W-C, Parry, DM, Roberts, A, Soffe, SR   +4 more
core   +2 more sources

The Xenopus Chk1 Protein Kinase Mediates a Caffeine-sensitive Pathway of Checkpoint Control in Cell-free Extracts [PDF]

, 1998
We have analyzed the role of the protein kinase Chk1 in checkpoint control by using cell-free extracts from Xenopus eggs. Recombinant Xenopus Chk1 (Xchk1) phosphorylates the mitotic inducer Cdc25 in vitro on multiple sites including Ser-287.
Dunphy, William G., Emami, Katayoon H., Guo, Zijian, Kumagai, Akiko, Wang, Sophie X.   +4 more
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The Mre11-Rad50-Nbs1 complex mediates activation of TopBP1 by ATM [PDF]

, 2009
The activation of ATR-ATRIP in response to double-stranded DNA breaks (DSBs) depends upon ATM in human cells and Xenopus egg extracts. One important aspect of this dependency involves regulation of TopBP1 by ATM.
Abraham R. T., Akiko Kumagai, Andrej Shevchenko, Anna Shevchenko, Bakkenist C. J., Byun T. S., Caldecott K. W., Chapman J. R., Cimprich K. A., Cortez D., Costanzo V., Costanzo V., Cuadrado M., Daniel J. Lew, Delacroix S., Garcia V., Glover J. N., Goldberg M., Guo Z., Hae Yong Yoo, Hashimoto Y., Jazayeri A., Kobayashi T., Kumagai A., Kumagai A., Kumagai A., Kumagai A., Lee J., Lee J. H., Liu Q., Melander F., Mordes D. A., Morishima K., Myers J. S., Nyberg K. A., Parrilla-Castellar E. R., Perry J. A., Qin X. F., Rupnik A., Sancar A., Shevchenko A., Shiloh Y., Spycher C., Stewart G. S., Walter J., Waridel P., William G. Dunphy, Williams R. S., Wu L., Yoo H. Y., Yoo H. Y., Yoo H. Y., Yoo H. Y., You Z., You Z., Zhao H., Zou L.   +56 more
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Normal levels of p27Xic1 are necessary for somite segmentation and determining pronephric organ size [PDF]

, 2009
The Xenopus laevis cyclin dependent kinase inhibitor p27Xic1 has been shown to be involved in exit from the cell cycle and differentiation of cells into a quiescent state in the nervous system, muscle tissue, heart and retina.
Anna Philpott, Barnett MW, Bassez T, Brändli AW, Carroll T, Chen J, Dale L, Daniels M, Di Cunto F, Elizabeth A. Jones, Greenwood J, Haldin CE, Hardcastle Z, Harland RM, Harlow E, Harris WA, Hartley RS, Jin X, Jones EA, Jones EA, Mauch TJ, Mitchell T, Moody SA, Movassagh M, Nguyen L, Nieuwkoop PD, Ohnuma S, Ohnuma S, Ozato K, Philpott A, Polyak K, Primmett DR, Reggiani L, Reynaud EG, Reynaud EG, Richard W. Naylor, Robert J. Collins, Saxén L, Seufert DW, Shou W, Snow MHL, Stern CD, Su JY, Thayer MJ, Vernon AE, Vernon AE, Vize PD, Wang Z, Zezula J   +48 more
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Hes6 acts in a positive feedback loop with the neurogenins to promote neuronal differentiation [PDF]

, 2000
During the development of the vertebrate nervous system, neurogenesis is promoted by proneural bHLH proteins such as the neurogenins, which act as potent transcriptional activators of neuronal differentiation genes.
Anderson­, David J., Kim, Jaesang, Kintner, Chris, Koyano-Nakagawa, Naoko   +3 more
core  

XenDB: Full length cDNA prediction and cross species mapping in Xenopus laevis [PDF]

, 2005
BACKGROUND: Research using the model system Xenopus laevis has provided critical insights into the mechanisms of early vertebrate development and cell biology.
Altmann, Curtis R, Beckstette, Michael, Brivanlou, Ali H, Giegerich, Robert, Sczyrba, Alexander   +4 more
core   +5 more sources