Results 31 to 40 of about 167,815 (303)

Retinoic acid-activated Ndrg1a represses Wnt/β-catenin signaling to allow Xenopus pancreas, oesophagus, stomach, and duodenum specification. [PDF]

PLoS ONE, 2013
How cells integrate multiple patterning signals to achieve early endoderm regionalization remains largely unknown. Between gastrulation and neurulation, retinoic acid (RA) signaling is required, while Wnt/β-catenin signaling has to be repressed for the ...
Tiejun Zhang, Xiaogang Guo, Yonglong Chen   +2 more
doaj   +1 more source

QuickProt: A Fast and Accurate Homology-Based Protein Annotation Tool for Non-Model Organisms to Advance Comparative Genomics. [PDF]

Mol Ecol Resour
ABSTRACT The rapid growth of genome sequencing has outpaced the development of efficient annotation tools, especially for species lacking transcriptome data. To address this challenge, we present QuickProt, a fast, accurate and user‐friendly homology‐based protein annotation tool.
Chen G, Du H, Cao Z, Wu Y, Zhang C, Zhou Y, Ao J, Sun Y, Yuan Z.   +8 more
europepmc   +2 more sources

Evi5 is required for Xenopus limb and tail regeneration

Frontiers in Cell and Developmental Biology, 2022
Amphibians such as salamanders and the African clawed frog Xenopus are great models for regeneration studies because they can fully regenerate their lost organs.
Li Yang, Youwei Chen, Huahua Liu, Yu Liu, Feng Yuan, Qianyan Li, Gufa Lin   +6 more
doaj   +1 more source

mNanog possesses dorsal mesoderm-inducing ability by modulating both BMP and Activin/nodal signaling in Xenopus ectodermal cells. [PDF]

PLoS ONE, 2012
BACKGROUND:In Xenopus early embryogenesis, various genes are involved with mesoderm formation. In particular, dorsal mesoderm contains the organizer region and induces neural tissues through the inhibition of bone morphogenetic protein (BMP) signaling ...
Aya Miyazaki, Kentaro Ishii, Satoshi Yamashita, Susumu Nejigane, Shinya Matsukawa, Yuzuru Ito, Yasuko Onuma, Makoto Asashima, Tatsuo Michiue   +8 more
doaj   +1 more source

The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3.

Genes & Development, 1996
The serine/threonine kinase Xgsk-3 and the intracellular protein beta-catenin are necessary for the establishment of the dorsal-ventral axis in Xenopus.
C. Yost, M. Torres, Jeffrey R. Miller, Eugene Y. Huang, D. Kimelman, R. Moon   +5 more
semanticscholar   +1 more source

Comparative Analysis of Cartilage Marker Gene Expression Patterns during Axolotl and Xenopus Limb Regeneration. [PDF]

PLoS ONE, 2015
Axolotls (Ambystoma mexicanum) can completely regenerate lost limbs, whereas Xenopus laevis frogs cannot. During limb regeneration, a blastema is first formed at the amputation plane.
Kazumasa Mitogawa, Aki Makanae, Ayano Satoh, Akira Satoh   +3 more
doaj   +1 more source

Ferritin‐Doped Nanoparticles Triggered Tumor‐Specific Darkening for Enhanced Photothermal Tumor Ablation and Immune Activation

Advanced Healthcare Materials, EarlyView.
Ferritin‐doped hybrid nanoparticles triggered accurate tumor‐specific hemorrhage for enhanced in situ photothermal therapy and evoked anti‐tumor immunity. Notably, HFn/GA‐Fe specifically induced tumor hemorrhage 12 h after intravenous injection, resulting in visible color darkening. Through photoacoustic imaging, tumor vessels could be clearly observed
Haidong Zha, Xiao Liang, Long Xi, Jiamao Chen, Wenzhao Zhong, Zhen Yuan, Meng Xu, Ying Zheng   +7 more
wiley   +1 more source

Amputation-induced reactive oxygen species (ROS) are required for successful Xenopus tadpole tail regeneration

Nature Cell Biology, 2013
Understanding the molecular mechanisms that promote successful tissue regeneration is critical for continued advancements in regenerative medicine.
Nick R. Love, Yaoyao Chen, Shoko Ishibashi, Paraskevi Kritsiligkou, R. Lea, Yvette Koh, J. Gallop, Karel Dorey, E. Amaya   +8 more
semanticscholar   +1 more source

High‐Throughput In Vivo Screening Using Barcoded mRNA Identifies Lipid Nanoparticles With Extrahepatic Tropism for In Situ Immunoengineering

Advanced Materials, EarlyView.
A high‐throughput in vivo mRNA LNP screening platform is developed and employed to screen a large library of 122 mRNA LNPs in vivo for delivery to immune, stromal, and parenchymal cells, identifying promising LNP candidates. A novel small particle flow cytometry‐based protein adsorption analysis method is utilized to interrogate protein corona ...
Alex G. Hamilton, Ajay S. Thatte, Junchao Xu, Zhangyi Luo, Hannah C. Safford, Kelsey L. Swingle, Jenna Muscat‐Rivera, Michael Kegel, Xuexiang Han, Ryann A. Joseph, Amanda M. Murray, Hannah C. Geisler, Ricardo C. Whitaker, Lulu Xue, Roman Spektor, Jilian R. Melamed, Drew Weissman, Michael J. Mitchell   +17 more
wiley   +1 more source

Elucidating nuclear size control in the Xenopus model system [PDF]

Veterinarski Glasnik, 2018
Background. Nuclear size is a tightly regulated cellular feature. Mechanisms that regulate nuclear size and the functional significance of this regulation are largely unknown. Nuclear size and morphology are often altered in many diseases, such as cancer.
Jevtić Predrag, Levy Daniel L.
doaj   +1 more source