Results 31 to 40 of about 121,926 (279)

Generation and Care of Xenopus laevis and Xenopus tropicalis Embryos [PDF]

open access: yes, 2018
Robust and efficient protocols for fertilization and early embryo care of Xenopus laevis and Xenopus tropicalis are essential for experimental success, as well as maintenance and propagation of precious animal stocks. The rapid growth of the National Xenopus Resource has required effective implementation and optimization of these protocols.
Marcin, Wlizla   +2 more
openaire   +2 more sources

Dusp1 modulates activin/smad2 mediated germ layer specification via FGF signal inhibition in Xenopus embryos

open access: yesAnimal Cells and Systems, 2020
Activin, a member of the transforming growth factor (TGF-β) superfamily, induces mesoderm, endoderm and neuro-ectoderm formation in Xenopus embryos. Despite several previous studies, the complicated gene regulatory network and genes involved in this ...
Zobia Umair   +9 more
doaj   +1 more source

Reversible Thiol Oxidation Inhibits the Mitochondrial ATP Synthase in Xenopus Laevis Oocytes

open access: yesAntioxidants, 2020
Oocytes are postulated to repress the proton pumps (e.g., complex IV) and ATP synthase to safeguard mitochondrial DNA homoplasmy by curtailing superoxide production. Whether the ATP synthase is inhibited is, however, unknown.
James Cobley   +4 more
doaj   +1 more source

Mechanisms of tail resorption during anuran metamorphosis

open access: yesBiomolecular Concepts, 2017
Amphibian metamorphosis has historically attracted a good deal of scientific attention owing to its dramatic nature and easy observability. However, the genetic mechanisms of amphibian metamorphosis have not been thoroughly examined using modern ...
Nakai Yuya   +2 more
doaj   +1 more source

Actin in Xenopus oocytes [PDF]

open access: yesThe Journal of cell biology, 1978
It has been found that a high-speed supernatant fraction from Xenopus oocytes extracted in the cold will form a clear, solid gel upon warming. Gel formation occurs within 60 min at 18 degrees-40 degrees C, and is, at least initially, temperature reversible. Gelation is strictly dependent upon the addition of sucrose to the extraction medium.
T G, Clark, R W, Merriam
openaire   +2 more sources

Functional limb muscle innervation prior to cholinergic transmitter specification during early metamorphosis in Xenopus

open access: yeseLife, 2018
In vertebrates, functional motoneurons are defined as differentiated neurons that are connected to a central premotor network and activate peripheral muscle using acetylcholine.
Francois M Lambert   +7 more
doaj   +1 more source

Retinoic acid-activated Ndrg1a represses Wnt/β-catenin signaling to allow Xenopus pancreas, oesophagus, stomach, and duodenum specification. [PDF]

open access: yesPLoS ONE, 2013
How cells integrate multiple patterning signals to achieve early endoderm regionalization remains largely unknown. Between gastrulation and neurulation, retinoic acid (RA) signaling is required, while Wnt/β-catenin signaling has to be repressed for the ...
Tiejun Zhang   +2 more
doaj   +1 more source

5-HT2B-mediated serotonin signalling participates in retinal and craniofacial morphogenesis during Xenopus laevis development

open access: yes, 2007
Serotonin (5HT) is a neurotransmitter that mediates a wide variety of effects in the central and peripheral adult nervous system. Experimental evidences demonstrated that serotonin even has an important role as growth and differentiating factor for ...
I. NARDI   +6 more
core   +1 more source

Evi5 is required for Xenopus limb and tail regeneration

open access: yesFrontiers in Cell and Developmental Biology, 2022
Amphibians such as salamanders and the African clawed frog Xenopus are great models for regeneration studies because they can fully regenerate their lost organs.
Li Yang   +6 more
doaj   +1 more source

Transposon transgenesis in Xenopus [PDF]

open access: yesMethods, 2010
Transposon-mediated integration strategies in Xenopus offer simple and robust methods for the generation of germline transgenic animals. Co-injection of fertilized one-cell embryos with plasmid DNA harboring a transposon transgene and synthetic mRNA encoding the cognate transposase enzyme results in mosaic integration of the transposon at early ...
Donald A, Yergeau   +4 more
openaire   +2 more sources

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