Results 31 to 40 of about 92,735 (222)
Advanced Science, EarlyView.We uncover a large variety of putative inhibitory ligand‐gated ion channels (LGICs) in the phylum Cnidaria, the sister group to all bilaterian animals. Phylogenetic analysis suggests a complex evolutionary history of inhibitory LGICs with diverse neurotransmitter ligands.
Abhilasha Ojha +13 more
wiley +1 more source
Elucidating nuclear size control in the Xenopus model system [PDF]
Veterinarski Glasnik, 2018 Background. Nuclear size is a tightly regulated cellular feature. Mechanisms that regulate nuclear size and the functional significance of this regulation are largely unknown. Nuclear size and morphology are often altered in many diseases, such as cancer.
Jevtić Predrag, Levy Daniel L.
doaj +1 more source
Kinesin‐Induced Buckling Reveals the Limits of Microtubule Self‐Repair
Advanced Science, EarlyView.This study shows that kinesin‐driven buckling induces extensive microtubule lattice damage that often exceeds intrinsic self‐repair and leads to filament failure. While curvature, motor motility, and force individually cause limited damage, their combination overwhelms repair.
Shweta Nandakumar +9 more
wiley +1 more source
Xenopus Models of Cancer: Expanding the Oncologist’s Toolbox
Frontiers in Physiology, 2018 The use of the Xenopus model system has provided diverse contributions to cancer research, not least because of the striking parallels between tumour pathogenesis and early embryo development.
Laura J. A. Hardwick +4 more
doaj +1 more source
Xenbase: Facilitating the Use of Xenopus to Model Human Disease
Frontiers in Physiology, 2019 At a fundamental level most genes, signaling pathways, biological functions and organ systems are highly conserved between man and all vertebrate species. Leveraging this conservation, researchers are increasingly using the experimental advantages of the
Mardi J. Nenni +15 more
doaj +1 more source
The Anatomical Record, EarlyView.Abstract Stages of embryonic development for reptiles have been presented in tables that may include all or part of embryonic development. When oviposition occurs in some lizards, embryos are already in the later stages of development; likewise, the size of the eggs increases as incubation time progresses.
Nivia Rocio Antonio‐Rubio +3 more
wiley +1 more source
Journal of Cardiovascular Development and Disease, 2016 The African clawed frog, Xenopus, is a valuable non-mammalian model organism to investigate vertebrate heart development and to explore the underlying molecular mechanisms of human congenital heart defects (CHDs).
Annemarie Hempel, Michael Kühl
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The skin microbiome of Xenopus laevis and the effects of husbandry conditions
Animal Microbiome, 2021 Background Historically the main source of laboratory Xenopus laevis was the environment. The increase in genetically altered animals and evolving governmental constraints around using wild-caught animals for research has led to the establishment of ...
Maya Z. Piccinni +4 more
doaj +1 more source
Animal Research and One Health, EarlyView.This review critically evaluates clotrimazole as a potential antifungal for finfish aquaculture, highlighting strong mechanistic and in vitro efficacy against aquatic mycoses alongside major gaps in in vivo evidence, toxicokinetics, residue safety, and environmental risk, outlining priorities for responsible therapeutic development and regulatory ...
Arya Sen +2 more
wiley +1 more source
Genetic code expansion for chemosensing and chemical actuation of biological functions
Bulletin of the Korean Chemical Society, EarlyView.Genetic code expansion (GCE) broadens the chemical repertoire for precise control of protein function in biological systems. This review highlights GCE‐based sensing and actuating systems that operate through selective interactions between noncanonical amino acids and chemical triggers.
Jieun Bae, Dong‐Hyun Kim, Minseob Koh
wiley +1 more source