Evolutionary importance of translation elongation factor eEF1A variant switching:eEF1A1 down-regulation in muscle is conserved in Xenopus but is controlled at a post-transcriptional level [PDF]
, 2011 Translation elongation isoform eEF1A1 has a pivotal role in protein synthesis and is almost ubiquitously expressed. In mice and rats that transcription of the gene encoding eEF1A1 is downregulated to undetectable levels in muscle after weaning; eEF1A1 is
Abbott, Catherine M +3 more
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Zoological Letters, 2018 Background DNA transposons are generally destroyed by mutations and have short lifespans in hosts, as they are neutral or harmful to the host and therefore not conserved by natural selection.
Akira Hikosaka, Seigo Konishi
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Patterns of tubb2b Promoter-Driven Fluorescence in the Forebrain of Larval Xenopus laevis
Frontiers in Neuroanatomy, 2022 Microtubules are essential components of the cytoskeleton of all eukaryotic cells and consist of α- and β-tubulin heterodimers. Several tissue-specific isotypes of α- and β-tubulins, encoded by distinct genes, have been described in vertebrates.
Daniela Daume +3 more
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Characterization of atrazine-induced gonadal malformations in African clawed frogs (Xenopus laevis) and comparisons with effects of an androgen antagonist (cyproterone acetate) and exogenous estrogen (17beta-estradiol): Support for the demasculinization/feminization hypothesis. [PDF]
, 2006 Atrazine is a potent endocrine disruptor that both chemically castrates and feminizes male amphibians. It depletes androgens in adult frogs and reduces androgen-dependent growth of the larynx in developing male larvae.
Collins, Atif +8 more
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Phosphorylation by Cdk1 increases the binding of Eg5 to microtubules in vitro and in Xenopus egg extract spindles. [PDF]
PLoS ONE, 2008 BACKGROUND:Motor proteins from the kinesin-5 subfamily play an essential role in spindle assembly during cell division of most organisms. These motors crosslink and slide microtubules in the spindle.
Julie Cahu +8 more
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Obtaining Xenopus laevis Embryos
Cold Spring Harbor Protocols, 2020 The embryos of the African clawed frog, Xenopus laevis, are a powerful substrate for the study of complex fundamental biological and disease mechanisms in neurobiology, physiology, molecular biology, cell biology, and developmental biology. A simple and straightforward technique for generating a large number of developmentally synchronized embryos is ...
Nikko-Ideen, Shaidani +3 more
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Microinjection of Xenopus Laevis Oocytes [PDF]
Journal of Visualized Experiments, 2009 Microinjection of Xenopus laevis oocytes followed by thin-sectioning electron microscopy (EM) is an excellent system for studying nucleocytoplasmic transport. Because of its large nucleus and high density of nuclear pore complexes (NPCs), nuclear transport can be easily visualized in the Xenopus oocyte.
Cohen, Sarah, Au, Shelly, Panté, Nelly
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A Model for Investigating Developmental Eye Repair in Xenopus Laevis [PDF]
, 2018 Vertebrate eye development is complex and requires early interactions between neuroectoderm and surface ectoderm during embryogenesis. In the African clawed frog, Xenopus laevis, individual eye tissues such as the retina and lens can undergo regeneration.
Kha, Cindy X. +3 more
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A NuRD Complex from Xenopus laevis Eggs Is Essential for DNA Replication during Early Embryogenesis
Cell Reports, 2018 Summary: DNA replication in the embryo of Xenopus laevis changes dramatically at the mid-blastula transition (MBT), with Y RNA-independent random initiation switching to Y RNA-dependent initiation at specific origins.
Christo P. Christov +6 more
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Cooperation behavior of fore‐ And hindlimbs during jumping in Rana dybowskii and Xenopus laevis
Ecology and Evolution, 2021 Frogs are characterized by their outstanding jumping ability, depending on the rapid extension of hindlimbs to propel their bodies into air. A typical jumping cycle could be broken into four phases: preparation, takeoff, flight, and landing. Considerable
Mo Li +6 more
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