Characterization of atrazine-induced gonadal malformations in African clawed frogs (Xenopus laevis) and comparisons with effects of an androgen antagonist (cyproterone acetate) and exogenous estrogen (17beta-estradiol): Support for the demasculinization/feminization hypothesis. [PDF]
, 2006 Atrazine is a potent endocrine disruptor that both chemically castrates and feminizes male amphibians. It depletes androgens in adult frogs and reduces androgen-dependent growth of the larynx in developing male larvae.
Collins, Atif +8 more
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Characterization of Xenopus tissue inhibitor of metalloproteinases-2: a role in regulating matrix metalloproteinase activity during development. [PDF]
PLoS ONE, 2012 Frog metamorphosis is totally dependent on thyroid hormone (T3) and mimics the postembryonic period around birth in mammals. It is an excellent model to study the molecular basis of postembryonic development in vertebrate.
Liezhen Fu +3 more
doaj +1 more source
Transcriptionally inactive oocyte-type 5S RNA genes of Xenopus laevis are complexed with TFIIIA in vitro [PDF]
, 1987 An extract from whole oocytes of Xenopus laevis was shown to transcribe somatic-type 5S RNA genes approximately 100-fold more efficiently than oocyte-type 5S RNA genes.
Eversole-Cire, Pamela +4 more
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Notch activates Wnt-4 signalling to control medio-lateral patterning of the pronephros [PDF]
, 2009 Previous studies have highlighted a role for the Notch signalling pathway during pronephrogenesis in the amphibian Xenopus laevis, and in nephron development in the mammalian metanephros, yet a mechanism for this function remains elusive.
Jones, E. A., Naylor, Richard William
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RMND5 from Xenopus laevis is an E3 ubiquitin-ligase and functions in early embryonic forebrain development. [PDF]
PLoS ONE, 2015 In Saccharomyces cerevisiae the Gid-complex functions as an ubiquitin-ligase complex that regulates the metabolic switch between glycolysis and gluconeogenesis.
Thorsten Pfirrmann +5 more
doaj +1 more source
Of Frogs & Rhetoric: The Atrazine Wars [PDF]
, 2015 In a scientific dispute over the effects of atrazine on amphibians, chemical industry–funded and publically funded scientists present stunningly contrasting constructions of atrazine\u27s environmental concentrations, persistence, and potential to harm ...
Reeves, Carol
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Synuclein Analysis in Adult Xenopus laevis
International Journal of Molecular Sciences, 2022 The α-, β- and γ-synucleins are small soluble proteins expressed in the nervous system of mammals and evolutionary conserved in vertebrates. After being discovered in the cartilaginous fish Torpedo californica, synucleins have been sequenced in all vertebrates, showing differences in the number of genes and splicing isoforms in different taxa. Although
Maria Carmela Bonaccorsi di Patti +5 more
openaire +3 more sources
Xenopus Hybrids Provide Insight Into Cell and Organism Size Control
Frontiers in Physiology, 2018 Determining how size is controlled is a fundamental question in biology that is poorly understood at the organismal, cellular, and subcellular levels. The Xenopus species, X. laevis and X. tropicalis differ in size at all three of these levels.
Romain Gibeaux +4 more
doaj +1 more source
Regional requirements for Dishevelled signaling during Xenopus gastrulation: separable effects on blastopore closure, mesendoderm internalization and archenteron formation [PDF]
, 2004 During amphibian gastrulation, the embryo is transformed by the combined actions of several different tissues. Paradoxically, many of these morphogenetic processes can occur autonomously in tissue explants, yet the tissues in intact embryos must interact
Ewald, Andrew J. +4 more
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Lipids of Xenopus laevis Spermatozoa [PDF]
Development, Growth & Differentiation, 1992 Xenopus laevis sperm lipid composition has been studied. The cholesterol content of Xenopus spermatozoa is 194 μ/mg DNA. Their content of glycolipids and phospholipids (measured as inorganic phosphorus) is respectively 40 and 27 μ/mg DNA. The phospholipid pattern is quite homogeneous and all the principal molecular species are present.
BERNARDINI, GIOVANNI BATTISTA +4 more
openaire +3 more sources