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Developmental Genetics in Xenopus tropicalis

2011
The diploid pipid frog Xenopus tropicalis has recently emerged as a powerful new model system for combining genetic and genomic analysis of tetrapod development with embryological and biochemical assays. Its early development closely resembles that of its well-understood tetraploid relative Xenopus laevis, from which techniques and reagents can be ...
Timothy J, Geach, Lyle B, Zimmerman
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Construction of BAC library for the amphibian Xenopus tropicalis

open access: yesGenes and Genetic Systems, 2004
Xenopus tropicalis has become an alternative model to the amphibian Xenopus laevis because it is better suited for genetic and genomic studies. We have constructed a genomic BAC library consisting of over 100,000 clones from sperm of Xenopus tropicalis. Analysis by pulsed field gel electrophoresis of representative BAC clones indicated the average size
Takeshi Yagi, Nobuyoshi Shimizu
exaly   +4 more sources

Best Practices forXenopus tropicalisHusbandry

Cold Spring Harbor Protocols, 2022
Xenopus tropicalishas been adopted by laboratories as a developmental genetic system because of its diploid genome and short generation time, contrasting withXenopus laevis, which is allotetraploid and takes longer to reach sexual maturity. BecauseX.
Takuya Nakayama, Robert M. Grainger
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Xenopus tropicalis Oocytes

2006
For more than 30 yr, Xenopus laevis has been the animal of choice for studying the biochemical regulation of the meiotic and early mitotic vertebrate cell cycles. Attracted by its diploid genome, several laboratories have begun using the similar, although evolutionarily distinct, frog Xenopus tropicalis for studies of vertebrate development ...
Jean-François L. Bodart   +1 more
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Cornea-lens transdifferentiation in the anuran, Xenopus tropicalis

Development Genes and Evolution, 2001
Previously, the only anuran amphibian known to regenerate the lens of the eye was Xenopus laevis. This occurs during larval stages through transdifferentiation of the outer cornea epithelium under control of factors presumably secreted by the neural retina. This study demonstrates that a distantly related species, X.
J J, Henry, M B, Elkins
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Navigating the Xenopus tropicalis Genome

2012
The frog Xenopus laevis has for more than 60 years served as a model system for the study of vertebrate embryogenesis, molecular and cell biology, and physiology. Recently, there has been great interest in the related species Xenopus tropicalis, in part because it is diploid, unlike the allotetraploid X.
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Genetic and genomic prospects for Xenopus tropicalis research

Seminars in Cell & Developmental Biology, 2006
Research using Xenopus laevis has made enormous contributions to our understanding of vertebrate development, control of the eukaryotic cell cycle and the cytoskeleton. One limitation, however, has been the lack of systematic genetic studies in Xenopus to complement molecular and cell biological investigations.
Samantha, Carruthers, Derek L, Stemple
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Teratogenic effects of tetrabromobisphenol A on Xenopus tropicalis embryos

Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 2010
Tetrabromobisphenol A (TBBPA) is the most widely used brominated flame retardant and a known thyroid disruptor. We reported exposing Xenopus tropicalis embryos (NF10) to 0.01, 0.1 or 1 mg/L of TBBPA with or without 70 microg/L triiodothyronine (T(3)). Compared with the controls, 1 mg/L of TBBPA significantly reduced the body length of embryos after 24,
Huahong, Shi   +5 more
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Frog genetics: Xenopus tropicalis jumps into the future

Trends in Genetics, 1998
. The two mainreasons for this are that the embryosdevelop externally and their relativelylarge size allows embryologists toperform microsurgery and manipu-late the embryos experimentally inways that are not as easy in other ver-tebrate embryos (e.g. mouse or zebra-fish).
Amaya, E.; id_orcid 0000-0002-1805-8548   +2 more
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Karyotype analysis of Xenopus tropicalis Gray, Pipidae

Cytogenetics and Cell Genetics, 2008
A cytological analysis of the anuran species Xenopus tropicalis was performed. The diploid chromosome number is 2n = 20, whereas two other Xenopus species previously analyzed, laevis and muelleri, have 2n = 36. In X. tropicalis the morphology of the various chromosome groups differs from the other two species.
openaire   +2 more sources

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