Results 11 to 20 of about 842 (148)

OmpR Indirectly Regulates Biosynthesis of Xenocoumacin 1 in <i>Xenorhabdus nematophila</i>. [PDF]

Microorganisms
Xenorhabdus nematophila has excellent potential for application in both medicine and agriculture due to its various active secondary metabolites. The transcriptional regulator OmpR negatively regulates Xenocoumacin 1 (Xcn1), which has wide antimicrobial activity.
Han Y, Zhao X, He M, Zhang S, Tang G, Wang Y.   +5 more
europepmc   +4 more sources

Regulation of antimicrobial activity and xenocoumacins biosynthesis by pH in Xenorhabdus nematophila. [PDF]

Microb Cell Fact, 2017
Xenocoumacin 1 (Xcn1) and Xenocoumacin 2 (Xcn2) are the main antimicrobial compounds produced by Xenorhabdus nematophila. Culture conditions, including pH, had remarkably distinct effects on the antimicrobial activity of X. nematophila. However, the regulatory mechanism of pH on the antimicrobial activity and antibiotic production of this bacterium is ...
Guo S, Zhang S, Fang X, Liu Q, Gao J, Bilal M, Wang Y, Zhang X.   +7 more
europepmc   +10 more sources

CpxRA Regulates Mutualism and Pathogenesis in Xenorhabdus nematophila [PDF]

Applied and Environmental Microbiology, 2007
ABSTRACT The CpxRA signal transduction system, which in Escherichia coli regulates surface structure assembly and envelope maintenance, is involved in the pathogenic and mutualistic interactions of the entomopathogenic bacterium Xenorhabdus nematophila . When Δ cpxR1
Erin E, Herbert, Kimberly N, Cowles, Heidi, Goodrich-Blair   +2 more
  +9 more sources

Pleiotropic role of PAX cyclolipopeptides in the <i>Xenorhabdus</i> bacterium mutualistically associated with entomopathogenic nematodes. [PDF]

Appl Environ Microbiol
Xenorhabdus is an entomopathogenic bacterium involved in a mutualistic relationship with Steinernema nematodes. Xenorhabdus produces a multitude of specialized metabolites by non-ribosomal peptide synthetase (NRPS) pathways to mediate bacterium-nematode ...
Claveyroles N, Lanois-Nouri A, El Fannassi I, Ogier J-C, Pagès S, Chouchou A, Cazals G, Valette G, Carré-Mlouka A, Givaudan A.   +9 more
europepmc   +2 more sources

Studying the Symbiotic Bacterium Xenorhabdus nematophila in Individual, Living Steinernema carpocapsae Nematodes Using Microfluidic Systems. [PDF]

mSphere, 2018
Animal-microbe symbioses are ubiquitous in nature and scientifically important in diverse areas, including ecology, medicine, and agriculture.
Stilwell MD, Cao M, Goodrich-Blair H, Weibel DB.   +3 more
europepmc   +2 more sources

CpxR negatively regulates the production of xenocoumacin 1, a dihydroisocoumarin derivative produced by Xenorhabdus nematophila. [PDF]

Microbiologyopen, 2019
Xenocoumacin 1 (Xcn1), a major antimicrobial compound produced by Xenorhabdus nematophila, has great potential for use in agricultural productions. In this study, we evaluated the effects of CpxR, a global response regulator associated with the mutualism
Zhang S, Fang X, Tang Q, Ge J, Wang Y, Zhang X.   +5 more
europepmc   +2 more sources

Glucosinolate hydrolysis products suppress entomopathogenic nematodes in vitro but do not protect sequestering flea beetle larvae in vivo. [PDF]

Pest Manag Sci
The flea beetle's glucosinolate‐based chemical defense fails to protect larvae from nematode infection. However, the defense inhibits the nematode's symbiotic bacteria, thereby potentially impairing nematode reproduction and biocontrol success. Abstract BACKGROUND The efficacy of entomopathogenic nematodes (EPNs) in the biological control of insect ...
Körnig J, Beneš V, Manthey C, Reichelt M, Kunert G, Paetz C, Kutzschbach J, Lampe P, Kaltenpoth M, Beran F.   +9 more
europepmc   +2 more sources

The Global Transcription Factor Lrp Controls Virulence Modulation in Xenorhabdus nematophila. [PDF]

J Bacteriol, 2015
ABSTRACT The bacterium Xenorhabdus nematophila engages in phenotypic variation with respect to pathogenicity against insect larvae, yielding both virulent and attenuated subpopulations of cells from an isogenic culture. The global regulatory protein Lrp is necessary for X. nematophila
Hussa EA, Casanova-Torres ÁM, Goodrich-Blair H.   +2 more
europepmc   +4 more sources

Comparative Analysis of Xenorhabdus koppenhoeferi Gene Expression during Symbiotic Persistence in the Host Nematode. [PDF]

PLoS ONE, 2016
Species of Xenorhabdus and Photorhabdus bacteria form mutualistic associations with Steinernema and Heterorhabditis nematodes, respectively and serve as model systems for studying microbe-animal symbioses. Here, we profiled gene expression of Xenorhabdus
Ruisheng An, Parwinder S Grewal
doaj   +1 more source

Xenocin export by the flagellar type III pathway in Xenorhabdus nematophila. [PDF]

J Bacteriol, 2013
ABSTRACT The xenocin operon of Xenorhabdus nematophila consists of xciA and ximB genes encoding a 64-kDa xenocin and 42-kDa immunity protein to kill competing microbes in the insect larva.
Singh P, Park D, Forst S, Banerjee N.
europepmc   +4 more sources