Results 111 to 120 of about 31,863 (228)

Moral approval of xenotransplantation in Egypt: associations with religion, attitudes towards animals and demographic factors

BMC Medical Ethics
Xenotransplantation has great potential as an alternative to alleviate the shortage of organs for donation. However, given that the animal most suited for xenotransplantation is the pig, there are concerns that people in Muslim countries may be more ...
Gabriel Andrade, Eid AboHamza, Yasmeen Elsantil, AlaaEldin Ayoub, Dalia Bedewy   +4 more
doaj   +1 more source

Clinical xenotransplantation

Japanese Journal of Clinical Immunology, 2007
The growing numerical gap between the number of patients and available human donor organs have led to a revival interest in xenotransplantation. This review will mainly focus on the clinical affairs of xenotransplantation and the project of producing the gene modified pigs.
openaire   +2 more sources

The Role of Costimulation Blockade in Solid Organ and Islet Xenotransplantation

Journal of Immunology Research, 2017
Pig-to-human xenotransplantation offers a potential bridge to the growing disparity between patients with end-stage organ failure and graft availability.
Kannan P. Samy, James R. Butler, Ping Li, David K. C. Cooper, Burcin Ekser   +4 more
doaj   +1 more source

Directing mesenchymal stem cells to bone to augment bone formation and increase bone mass. [PDF]

, 2012
Aging reduces the number of mesenchymal stem cells (MSCs) that can differentiate into osteoblasts in the bone marrow, which leads to impairment of osteogenesis.
Guan, Min, Jia, Junjing, Lam, Kit S, Lane, Nancy E, Liu, Ruiwu, Meng, Liping, Nolta, Jan, Panganiban, Brian, Ritchie, Robert O, Shahnazari, Mohammad, Yao, Wei, Zhou, Ping   +11 more
core   +1 more source

Infection in xenotransplantation

BMJ, 2000
Advances in transplantation immunology have enhanced the possibility of xenotransplantation as a therapeutic option for end-stage organ failure. The potential spread of animal-derived pathogens to the recipient and to the general population, termed "xenosis," is a potential complication of interspecies transplantation.
openaire   +4 more sources

Donor pigs for clinical islet xenotransplantation: Review and future directions

Cell Transplantation
Allogeneic islet transplantation becomes a viable option for patients with unstable type 1 diabetes. However, considering the huge number of patients with type 1 diabetes, human donor shortage is a serious issue.
Shinichi Matsumoto, Sadaki Asari, Yoshihide Nanno, Hiroyuki Nakamura, Taisuke Okawa, Takumi Fukumoto   +5 more
doaj   +1 more source

Complement networks in gene-edited pig xenotransplantation: enhancing transplant success and addressing organ shortage

Journal of Translational Medicine
The shortage of organs for transplantation emphasizes the urgent need for alternative solutions. Xenotransplantation has emerged as a promising option due to the greater availability of donor organs.
Yinglin Yuan, Yuanyuan Cui, Dayue Zhao, Yuan Yuan, Yanshuang Zhao, Danni Li, Xiaomei Jiang, Gaoping Zhao   +7 more
doaj   +1 more source

Is it currently possible to evaluate the risk posed by PERVs for clinical xenotransplantation? [PDF]

, 2018
Denner, Joachim, Schuurman, Henk-Jan, Scobie, Linda   +2 more
core   +1 more source

Integrative analysis of swine infectious diseases in the context of xenotransplantation

International Journal of Infectious Diseases
Background: The initiation of clinical pig xenotransplantation trials offers the prospect of alleviating global organ shortage. However, current knowledge of swine-derived microorganisms relevant to xenotransplantation remains fragmented due to the ...
Jiayu Li, Kai Liu, Muhammad Ameen Jamal, Kaixiang Xu, Wenmin Cheng, Baoyu Jia, Hong-Ye Zhao, Hongzhou Lu, Jay A. Fishman, Hong-Jiang Wei   +9 more
doaj   +1 more source

Profound thrombocytopenia associated with administration of multiple anti‐inflammatory agents in baboons

Immunity, Inflammation and Disease, 2022
Mohamed H. Bikhet, Christophe Hansen‐Estruch, Mariyam Javed, Dalis E. Collins, Jeremy B. Foote, David Ayares, Hidetaka Hara, David K. C. Cooper   +7 more
doaj   +1 more source