Results 91 to 100 of about 31,863 (228)

Metabolism Controls the Timing of Human Brain Development and Maturation

Journal of Inherited Metabolic Disease, Volume 49, Issue 3, May 2026.
ABSTRACT Among primates the human brain is the largest in size, exhibiting a higher neuronal density and connectivity. The prolonged expansion and subsequent connectome reorganization of the human brain have been suggested to promote higher cognitive and behavioral abilities.
Valentina Rava, Erica Cannone, Maura Francolini, Elena Taverna   +3 more
wiley   +1 more source

In vivo imaging enables high resolution preclinical trials on patients' leukemia cells growing in mice. [PDF]

, 2012
Xenograft mouse models represent helpful tools for preclinical studies on human tumors. For modeling the complexity of the human disease, primary tumor cells are by far superior to established cell lines.
Brentjens, Renier J., Castro Alves, Catarina, Ehrhardt, Harald, Farkasova, Katarina, Groiss, Volker, Horstmann, Martin, Jeremias, Irmela, Ogris, Manfred, Quintanilla-Martinez, Leticia, Schneider, Katja, Terziyska, Nadia, Wagner, Ernst, zur Stadt, Udo   +12 more
core   +3 more sources

The Top Five Advances in Solid Organ Transplantation in the Past Fifty Years

World Journal of Surgery, EarlyView.
Stephen J. Wigmore, Diana A. Wu
wiley   +1 more source

Dual Use Research of Concern—The Necessity of Global Bioethics Engagement

Bioethics, Volume 40, Issue 4, Page 373-379, May 2026.
ABSTRACT Dual use research of concern (DURC) refers to research conducted for legitimate scientific purposes that could also be misused to pose a significant threat to public health and safety, agricultural crops and other plants, animals, the environment, or national security.
Daniel J. Hurst, Christopher A. Bobier
wiley   +1 more source

Characterization and phylogenetic analysis of the complete mitochondrial genome of Cotylorhiza tuberculata assembled using next-generation sequencing

Mitochondrial DNA. Part B. Resources
In this study, the complete mitochondrial genome (mitogenome) of Cotylorhiza tuberculata (Scyphozoa; Rhizostomeae; Cepheidae) was assembled by the next-generation sequencing data.
Hui Jiang, Wangxiao Xia, Shaoxia Pu, Yanhua Su, Anzhu Zhu, Hongye Zhao, Hongjiang Wei, Yaowen Liu   +7 more
doaj   +1 more source

Hamster-to-rat heart and liver xenotransplantation with FK506 plus antiproliferative drugs [PDF]

, 1993
Heterotopic hamster hearts transplanted to unmodified LEW rats underwent humoral rejection in 3 days. Survival was prolonged to a median of 4 days with 2 mg/kg/day FK506.
Cramer, D, Demetris, AJ, Makowka, L, Murase, N, Starzl, TE, Tanabe, M, Valdivia, L   +6 more
core   +1 more source

Laparoscopic Embryo Transfer in Swine: An Effective Alternative to Traditional Open Surgery

Reproduction in Domestic Animals, Volume 61, Issue 5, May 2026.
ABSTRACT While embryo transfer (ET) has not yet been widely adopted in the commercial swine industry, it is an essential tool in biomedical research, including the creation of gene‐edited pigs. Traditionally, ET in pigs is performed by open surgery (laparotomy), an effective but invasive and time‐consuming method associated with risks such as infection
H. Baldassarre, L. G. Currin, M. P. de Macedo, V. Guay, F. L. Facioli, R. Duffy, A. Ojerio, L. Socransky, Z. da Silva, K. Gutierrez, W. G. Glanzner, V. Bordignon   +11 more
wiley   +1 more source

A chromosome-scale reference genome of the Banna miniature inbred pig

Scientific Data
The Banna miniature inbred pig (BN) is an intensively inbred line for biomedical research and xenotransplantation due to its low individual variation and stable genetic background.
Hong-Man Chen, Kai-Xiang Xu, Chen Yan, Heng Zhao, De-Ling Jiao, Si Si, Zheng-Xi Liu, Guo-Ying Peng, Muhammad Ameen Jamal, Min-Juan Lv, Pei Wang, Yang-Zhi Zeng, Hong-Ye Zhao, Ming-Shan Wang, Hong-Jiang Wei   +14 more
doaj   +1 more source

Evidence for engraftment of human bone marrow cells in non-lethally irradiated baboons [PDF]

, 1997
Background. Prior to organ harvesting, an attempt was made to modulate the donor's immune responses against prospective xenogeneic recipients by infusion of 'recipient-type' bone marrow. Methods.
Fontes, P, Fung, JJ, Rao, AS, Ricordi, C, Rogers, J, Starzl, TE, Trucco, M, Zeevi, A   +7 more
core   +1 more source

Xenoperfusion—The Transformative Role of Machine Perfusion in Xenotransplantation

Xenotransplantation, Volume 33, Issue 3, May/June 2026.
ABSTRACT Recent advances in xenotransplantation have gained substantial public and clinical attention as genetically modified porcine organs are now being transplanted into living human recipients. While only case reports have been published to date, the first clinical trials for kidney xenotransplantation are now ongoing.
Florian Huwyler, Simon Stoerzer, Pierre‐Alain Clavien, Mark W. Tibbitt   +3 more
wiley   +1 more source