Results 91 to 100 of about 21,110 (223)

Xenotransplantation: Where do we stand in 2016? [PDF]

, 2017
Worldwide, there is a constant rise in the number of patients with end-stage organ failure in critical need for transplants, but the number of organs/cells available from deceased or living human donors is limited.
Leo Bhler, Henk-Jan Schuurman, Robert Rieben, Puga Yung, Gisella L, Puga Yung, Gisella, Rieben, Robert, Bühler, Leo, Jrg D. Seebach, Seebach, Jorg Dieter, Schuurman, Henk-Jan, Seebach, Jörg, Gisella L. Puga Yung, Buehler, Leo Hans   +12 more
core   +1 more source

3D-printed dictamni-calcium silicate scaffolds modulate the osteoimmune microenvironment and enhance macrophage-derived exosomal miR-21 signaling in vascularized bone regeneration

Journal of Nanobiotechnology
Reconstruction of critical-sized bone defects remains a formidable clinical challenge due to a persistent, localized, pro-inflammatory microenvironment that disrupts the coordinated process of osteogenic-angiogenic coupling.
Chia-Che Ho, Tuan-Ti Hsu, Yen-Hong Lin, Ting-You Kuo, Cheng-Yu Chen, Shang-Hsiu Hu, Jen-Ting Huang, Tsung-Li Lin, Der-Yang Cho, Ming-You Shie   +9 more
doaj   +1 more source

Is Allosensitization Detrimental to Pig Organ Xenotransplantation, and Is Xenosensitization Detrimental to Subsequent Organ Allotransplantation? A Debate Organized by the International Xenotransplantation Association (IXA) [PDF]

This report summarizes the content of a debate sponsored by eGenesis Bio, organized by the International Xenotransplantation Association (IXA), and attended by more than 150 delegates in the context of the IPITA‐IXA‐CTRMS Joint Congress held in San Diego
Kwun, Jean, Tector, A. Joseph, Knechtle, Stuart, Bühler, Léo H., Cooper, David K. C., Ladowski, Joseph, Jackson, Annette, Mangiola, Massimo, Cozzi, Emanuele, Tector, Alfred   +9 more
core   +1 more source

Detection of Pig Cells Harboring Porcine Endogenous Retroviruses in Non-Human Primate Bladder After Renal Xenotransplantation

Viruses, 2019
Pigs are used as potential donor animals for xenotransplantation. However, porcine endogenous retrovirus (PERV), shown to infect both human and non-human primate (NHP) cells in vitro, presents a risk of transmission to humans in xenotransplantation.
Yoonki Heo, Yeondong Cho, Keon Bong Oh, Ki Hoon Park, Hansam Cho, Hanul Choi, Minjee Kim, Ik Jin Yun, Hee Jung Lee, Young Bong Kim   +9 more
doaj   +1 more source

International Human Xenotransplantation Inventory [PDF]

, 2010
BACKGROUND: Xenotransplantation carries inherent risks of infectious disease transmission to the recipient and even to society at large, and it should only be carried out with strict regulation and oversight.
Sykes, Megan, Luc Noel, Sgroi, Antonino, Morel, Philippe, Noel, Luc, Philippe Morel, Antonino Sgroi, Leo H. Bühler, Megan Sykes, Buehler, Leo Hans   +9 more
core   +1 more source

Establishment of Allogeneic Kidney Transplantation Technical System in Banna Miniature Pig Inbred Strain

Shiyan dongwu yu bijiao yixue
ObjectiveTo establish a technical system for allogeneic kidney transplantation surgery in pigs using the Banna miniature pig inbred strain, and to evaluate it through routine blood tests, liver and kidney function tests, thus providing reference data for
ZHANG Ying, PENG Ziwei, YANG Chang, WANG Jing, ZHAO Hongfang, CHEN Gen, ZHAO Hongye, WEI Hongjiang   +7 more
doaj   +1 more source

Multi‐modified donor pigs for xenotransplantation [PDF]

, 2017
Wolf, Eckhard, Petersen, Björn, Fischer, Konrad*, Schnieke, Angelika, Rieblinger, Beate, Schwinzer, Reinhard, Schäffler, Andrea, Niemann, Heiner, Kind, Alexander   +8 more
core   +7 more sources

Increasing Follicular and Stromal Cell Proliferation in Cryopreserved Human Ovarian Tissue after Long-Term Precooling Prior to Freezing: In Vitro versus Chorioallantoic Membrane (CAM) Xenotransplantation

Cell Transplantation, 2013
A positive effect on the future development of cells, which have been cooled to low suprazero temperatures and then thawed, has been observed before and is not new.
Vladimir Isachenko, Evgenia Isachenko, Peter Mallmann, Gohar Rahimi   +3 more
doaj   +1 more source

The case for xenotransplantation [PDF]

Clinical Transplantation, 2015
AbstractThe availability of organs and cells from deceased humans for transplantation is not meeting the demand. Xenotransplantation, specifically the transplantation of organs and cells from genetically engineered pigs, could resolve this problem. Diabetic monkeys have remained normoglycemic and insulin‐independent after pig islet transplantation for &
openaire   +2 more sources

A chromosome-scale reference genome of the Banna miniature inbred pig

Scientific Data
The Banna miniature inbred pig (BN) is an intensively inbred line for biomedical research and xenotransplantation due to its low individual variation and stable genetic background.
Hong-Man Chen, Kai-Xiang Xu, Chen Yan, Heng Zhao, De-Ling Jiao, Si Si, Zheng-Xi Liu, Guo-Ying Peng, Muhammad Ameen Jamal, Min-Juan Lv, Pei Wang, Yang-Zhi Zeng, Hong-Ye Zhao, Ming-Shan Wang, Hong-Jiang Wei   +14 more
doaj   +1 more source