Results 81 to 90 of about 15,110 (190)

The Future of Pig Liver Xenotransplantation

open access: yesTransplant International
Recent technological advances in genetic engineering have led to a renewed interest in xenotransplantation. Milestones achievements in heart, kidney and more recently liver xenotransplantation raise the hope of an alternative source of organs and pave ...
Ahmad Karadagi   +3 more
doaj   +1 more source

Moral approval of xenotransplantation in Egypt: associations with religion, attitudes towards animals and demographic factors

open access: yesBMC Medical Ethics
Xenotransplantation has great potential as an alternative to alleviate the shortage of organs for donation. However, given that the animal most suited for xenotransplantation is the pig, there are concerns that people in Muslim countries may be more ...
Gabriel Andrade   +4 more
doaj   +1 more source

The Role of Costimulation Blockade in Solid Organ and Islet Xenotransplantation

open access: yesJournal of Immunology Research, 2017
Pig-to-human xenotransplantation offers a potential bridge to the growing disparity between patients with end-stage organ failure and graft availability.
Kannan P. Samy   +4 more
doaj   +1 more source

Donor pigs for clinical islet xenotransplantation: Review and future directions

open access: yesCell Transplantation
Allogeneic islet transplantation becomes a viable option for patients with unstable type 1 diabetes. However, considering the huge number of patients with type 1 diabetes, human donor shortage is a serious issue.
Shinichi Matsumoto   +5 more
doaj   +1 more source

Complement networks in gene-edited pig xenotransplantation: enhancing transplant success and addressing organ shortage

open access: yesJournal of Translational Medicine
The shortage of organs for transplantation emphasizes the urgent need for alternative solutions. Xenotransplantation has emerged as a promising option due to the greater availability of donor organs.
Yinglin Yuan   +7 more
doaj   +1 more source

Integrative analysis of swine infectious diseases in the context of xenotransplantation

open access: yesInternational Journal of Infectious Diseases
Background: The initiation of clinical pig xenotransplantation trials offers the prospect of alleviating global organ shortage. However, current knowledge of swine-derived microorganisms relevant to xenotransplantation remains fragmented due to the ...
Jiayu Li   +9 more
doaj   +1 more source

Profound thrombocytopenia associated with administration of multiple anti‐inflammatory agents in baboons

open access: yesImmunity, Inflammation and Disease, 2022
Mohamed H. Bikhet   +7 more
doaj   +1 more source

A Remarkable Journey of Porcine to Human Xenotransplantation

open access: yesIndian Journal of Transplantation
Xenotransplantation of pig hearts offers a potential solution to the scarcity of available human organs for transplantation. This abstract explores the challenges and risks associated with xenotransplantation, as well as the ongoing research and ...
Dhruva Sharma   +1 more
doaj   +1 more source

Generation and transcriptomic characterization of MIR137 knockout miniature pig model for neurodevelopmental disorders

open access: yesCell & Bioscience
Background Neurodevelopmental disorders (NDD), such as autism spectrum disorders (ASD) and intellectual disorders (ID), are highly debilitating childhood psychiatric conditions.
Shengyun Xu   +15 more
doaj   +1 more source

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