Results 81 to 90 of about 31,863 (228)

Xenotransplantation at a Crossroads: Breakthroughs, Challenges, and the Path Forward

Organ Medicine, EarlyView.
Xiaoyu Gan, Jizhang Yu, Jie Wu, Junjie Zong   +3 more
wiley   +1 more source

Engineered Microfluidic Organoid Systems: New Paradigms for Menopause Mechanism Research and Personalized Medicine

Advanced Materials Technologies, Volume 11, Issue 9, 6 May 2026.
This review explores the integration of microfluidic technology with organoid systems as an innovative platform for studying menopausea complex multi‐organ condition. By enabling precise simulation of inter‐organ communication and hormone responses, microfluidic organoids offer a physiologically relevant model for investigating menopausal syndrome and ...
Qianyi Zhang, He Huang, Hongliang Dong, Qiang Ma, Hongyan Jin   +4 more
wiley   +1 more source

Detection of Pig Cells Harboring Porcine Endogenous Retroviruses in Non-Human Primate Bladder After Renal Xenotransplantation

Viruses, 2019
Pigs are used as potential donor animals for xenotransplantation. However, porcine endogenous retrovirus (PERV), shown to infect both human and non-human primate (NHP) cells in vitro, presents a risk of transmission to humans in xenotransplantation.
Yoonki Heo, Yeondong Cho, Keon Bong Oh, Ki Hoon Park, Hansam Cho, Hanul Choi, Minjee Kim, Ik Jin Yun, Hee Jung Lee, Young Bong Kim   +9 more
doaj   +1 more source

Fludarabine as a cost-effective adjuvant to enhance engraftment of human normal and malignant hematopoiesis in immunodeficient mice [PDF]

, 2018
There is still an unmet need for xenotransplantation models that efficiently recapitulate normal and malignant human hematopoiesis. Indeed, there are a number of strategies to generate humanized mice and specific protocols, including techniques to ...
A Rambaldi, A Terenzi, AM Carroll, AM Carroll, BS Andersson, CR Giver, D Niederwieser, DA Frank, DE Mosier, E McCormack, F Aversa, IF Khouri, K Tajima, L Luznik, L Weiss, M Furukawa, NC Kirkiles-Smith, S Goyama   +17 more
core   +1 more source

Different Immune Cells Modified With Chimeric Antigen Receptors Are Being Applied to Ovarian Cancer: Which Is the Most Effective?

Cancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Ovarian Cancer (OC), the deadliest gynecological malignancy, poses a major therapeutic challenge in advanced stages owing to its high recurrence rate and metastatic potential. In this regard, it is noteworthy that immunotherapy has recently gained significant attention in OC treatment, a phenomenon attributable to notable advances in over‐the ...
Liying Wang, Yisen Cao, Yuan Ren, Yuhang Zhang, Liang Wang   +4 more
wiley   +1 more source

Establishment of Allogeneic Kidney Transplantation Technical System in Banna Miniature Pig Inbred Strain

Shiyan dongwu yu bijiao yixue
ObjectiveTo establish a technical system for allogeneic kidney transplantation surgery in pigs using the Banna miniature pig inbred strain, and to evaluate it through routine blood tests, liver and kidney function tests, thus providing reference data for
ZHANG Ying, PENG Ziwei, YANG Chang, WANG Jing, ZHAO Hongfang, CHEN Gen, ZHAO Hongye, WEI Hongjiang   +7 more
doaj   +1 more source

Increasing Follicular and Stromal Cell Proliferation in Cryopreserved Human Ovarian Tissue after Long-Term Precooling Prior to Freezing: In Vitro versus Chorioallantoic Membrane (CAM) Xenotransplantation

Cell Transplantation, 2013
A positive effect on the future development of cells, which have been cooled to low suprazero temperatures and then thawed, has been observed before and is not new.
Vladimir Isachenko, Evgenia Isachenko, Peter Mallmann, Gohar Rahimi   +3 more
doaj   +1 more source

Understanding Morality in the Religion-and-Science Context [PDF]

, 2012
Recent developments in biotechnology require re/definition of human \"being.\" In this paper, the author suggests that the term \"human being \" is substituted with \"human betweenness.\" This substitution emerges from a philosophical/theological reading
Park, Iljoon
core   +1 more source

Immunodepletion in xenotransplantation [PDF]

, 1990
Xenograft transplantation is perhaps the most immunologically difficult problem in transplantation today. An overwhelming hyperacute rejection reaction (HAR) occurs within minutes of organ implantation.
A. Casavilla, A. G. Tzakis, A. Oks, A. Oral, B. Banner, Branda R F, Forsgren A, Giles G R, J. Murray, K. Yanaga, L. Makowka, L. Podesta, Langone J J, P. D'andrea, R. Shapiro, R. Watt, S. Wos, T. E. Starzl, Ting A, V. Scantlebury   +19 more
core   +1 more source

Five Advances in the Last 50 Years: Liver Malignancies

World Journal of Surgery, EarlyView.
Alex B. Blair, Timothy M. Pawlik
wiley   +1 more source