Results 71 to 80 of about 31,863 (228)
Donor species complement after liver xenotransplantation: The mechanism of protection from hyperacute rejection [PDF]
, 1994 Hamster hearts transplanted into stable rat recipients of hamster livers (OLT rats) were hyperacutely rejected after transfer with unaltered rat antihamster hyperimmune serum (HS).
Celli, S +6 more
core +1 more source
Cell Proliferation, EarlyView.Clinical‐grade HLA‐homozygous iPSC‐derived neural precursor cells restore motor function, rebuild striatal circuitry and reduce neuroinflammation in QA‐lesioned rats. These findings demonstrate robust neuronal replacement and microenvironment modulation, supporting their potential as a regenerative therapy for Huntington's disease.
Hyeonjoong Jeon +6 more
wiley +1 more source
Data in Brief, 2018 This report is related to the research article entitled “B cell phenotypes in baboons with pig artery patch grafts receiving conventional immunosuppressive therapy” (Yamamoto et al., in press).
Takayuki Yamamoto +14 more
doaj +1 more source
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Background Type 1 diabetes mellitus (T1DM) is a chronic autoimmune disease marked by the destruction of pancreatic β‐cells, resulting in lifelong dependence on exogenous insulin. Despite advances in insulin delivery and glucose monitoring technologies, patients remain at risk for acute and long‐term complications, underscoring the need for ...
Tzu‐Min Lin +5 more
wiley +1 more source
The FEBS Journal, EarlyView.NOTCH signalling is indispensable for tissue homeostasis and, consequently, corruption of its normal function promotes numerous diseases, including cancer. However, the development of targeted therapies has been hampered by inefficacy and overt toxicity. Here, we show that NOTCH receptor dimerization is necessary for receptor transactivation, which has
Xinxin Liu +9 more
wiley +1 more source
Photochemistry and Photobiology, EarlyView.Zebrafish provide a high‐throughput, optically transparent platform for cancer and drug screening. Their ~80% genetic homology, xenograft compatibility, and transgenic strains enable targeted photosensitizer screening, real‐time ROS and tumor imaging, and mechanistic assays, while fish embryo acute toxicity (FET) and in vitro tests streamline toxicity ...
Ethan Wilson +5 more
wiley +1 more source
MicroorganismsThe beta T-cell receptor (TRB) expressed by beta T cells is essential for foreign antigen recognition. The TRB locus contains a TRBV family that encodes three complementarity determining regions (CDRs).
Jiayu Li +15 more
doaj +1 more source
Humoral and cellular immunopathology of hepatic and cardiac hamster-into-rat xenograft rejection: Marked stimulation of IgM++bright/IgD+dull splenic B cells [PDF]
, 1993 Normal Lewis rat serum contains antibodies (IgM > IgG) that bind to hamster leukocytes and endothelial cells. Transplantation of either the heart or liver from hamster rat results in release of hamster hematolymphoid cells from the graft, which lodge in ...
Celli, S +7 more
core
MedComm – Oncology, Volume 5, Issue 2, June 2026.This article systematically elucidates the molecular mechanisms of colorectal precancerous lesions, introduces cutting‐edge research tools like multi‐omics and organoids, and highlights the potential and prospects of natural products such as berberine, resveratrol, and curcumin in preventing and intervening in colorectal carcinogenesis by modulating ...
Shunji Liu +6 more
wiley +1 more source
Acute rejection is associated with antibodies to non-Gal antigens in baboons using Gal-knockout pig kidneys [PDF]
, 2005 We transplanted kidneys from α1,3-galactosyltransferase knockout (GalT-KO) pigs into six baboons using two different immunosuppressive regimens, but most of the baboons died from severe acute humoral xenograft rejection. Circulating induced antibodies to
Anthony Jevnikar +33 more
core +1 more source