Results 51 to 60 of about 23,059 (229)

Organ xenotransplantation acceptance in veterinary students: A multicentric opinion study in Spain

, 2023
2023 Acuerdos transformativos CRUEBackground: The shortage of available transplant organs has made it necessary to search for alternatives, one of which is xenotransplantation.
Fidel San Román‐Ascaso, Gómez Laguna, Jaime, Juan Manuel Herrero, López Chicheri, Isabel, Xavier Moll, Ana López‐Navas, José Luis Martin‐Barrasa, Ríos, Antonio, Antonio Ríos, Quereda, Juan José, Fernández, Olga María, Olga María Fernández, Jaime Gómez‐Laguna, Gutiérrez, Pedro, Ramis, Guillermo, Martínez Alarcón, Laura, Mendonça, Livia, Isabel López‐Chicheri, Herrero, Juan Manuel, Victoria Falceto, Pablo Ramírez, Muñoz, Antonio, San Román Ascaso, Fidel, Guillermo Ramis, Pedro Gutiérrez, San Román Llorens, Fidel, Juan Flores‐Medina, Fidel San Román‐Llorens, Falceto, Victoria, Flores Medina, Juan, Martín Barrasa, José Luis, López Navas, Ana, Livia Mendonça, Moll, Xavier, Antonio Muñoz, Ramírez, Pablo, Laura Martínez‐Alarcón, Juan José Quereda   +37 more
core   +1 more source

Health sciences students and their attitude toward islet xenotransplantation for diabetes: a multicenter stratified study from Spain

, 2019
Health sciences students and their attitude toward islet xenotransplantation for diabetes: a multicenter stratified study from ...
Santainés Borredá, Elena, Ramírez, Pablo, Martínez-Alarcón, Laura   +2 more
core   +3 more sources

Construction and Functional Validation of GTKO/hCD55 Gene-Edited Xenotransplant Donor Pigs

Shiyan dongwu yu bijiao yixue
Objective To develop GTKO (α-1,3-galactosyltransferase gene-knockout, GTKO)/hCD55 (human CD55) gene-edited xenotransplant donor pigs and verify their function. Methods In this study, CRISPR (clustered regularly interspaced short palindromic repeats)/Cas9
WANG Jiaoxiang, ZHANG Lu, CHEN Shuhan, JIAO Deling, ZHAO Heng, WEI Taiyun, GUO Jianxiong, XU Kaixiang, WEI Hongjiang   +8 more
doaj   +1 more source

Immunoglobulin G profile in hyperacute rejection after multivisceral xenotransplantation

, 2012
Galvao FHF, Soler W, Pompeu E, Waisberg DR, Mello ES, Costa ACL, Teodoro W, Velosa AP, Capelozzi VL, Antonangelo L, Catanozi S, Martins A, Malbouisson LMS, Cruz RJ, Figueira ER, Filho JAR, Chaib E, D'Albuquerque LAC.
Chaib, Eleazar, Soler, Wangles, Velosa, Ana P., Antonangelo, Leila, Cruz, Ruy J., Jr., Mello, Evandro S. D., Pompeu, Eduardo, Malbouisson, Luiz M. S., Figueira, Estela R., Teodoro, Walcy, Waisberg, Daniel R., Costa, Anderson C. L., Catanozi, Sergio, Filho, Joel A. R., D'Albuquerque, Luiz A. C., Galvao, Flavio H. F., Capelozzi, Vera L., Martins, Alessandro   +17 more
core   +1 more source

Korean attitudes to Xenotransplantation: A survey conducted in 2009

, 2018
Background: Xenotransplantation research has been being actively conducted in Korea. However, there are numbers of socio-ethical issues involved in this research, and it is necessary to know public attitudes toward the research, inducing &quot ...
권복규
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Generation and characterization of genetically modified pigs with GGTA1/β4GalNT2/CMAH knockout and human CD55/CD47 expression for xenotransfusion studies

Scientific Reports
Pig red blood cells (pRBCs) represent a promising alternative to address the shortage in transfusion medicine. Nonetheless, a major obstacle to their clinical implementation is immunological rejection.
Bin Fang, Chunting Wang, Yilin Yuan, Xiaorui Liu, Lili Shi, Lin Li, Ying Wang, Yifan Dai, Haiyuan Yang   +8 more
doaj   +1 more source

The Ethics of Xenotransplantation [PDF]

Journal of Applied Philosophy, 2000
Xenotransplantation--moving organs or cells from one species to another--is currently being actively researched as a possible contribution to the problem of a global shortage of human organs for transplants. Should xenotransplantation be encouraged, permitted, frowned upon or forbidden?
openaire   +4 more sources

Liver xenotransplantation [PDF]

Current Opinion in Organ Transplantation, 2017
There continues to be an inadequate organ supply and lack of effective temporary support, for patients with liver failure. The purpose of this review is to discuss recent progress in the field of orthotopic pig-to-nonhuman primate (NHP) liver xenotransplantation (LXT).From 1968 to 2012, survival in pig-to-NHP LXT was limited to 9 days, initially due to
Madhukar S, Patel, Nathan, Louras, Parsia A, Vagefi   +2 more
openaire   +2 more sources

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source