Results 91 to 100 of about 2,411 (230)
Rare Germline Variants in CDKN2A‐Negative Children and Adolescents With Cutaneous Melanoma
Individuals with childhood and adolescent melanoma carry inherited mutations in shelterin complex genes, pigmentation genes and MBD4, but have fewer MC1R R‐alleles than adults with melanoma. Created with BioRender.com. ABSTRACT Cutaneous melanoma is a complex disease influenced by both environmental and genetic factors. Inherited susceptibility plays a
Peter A. Johansson +10 more
wiley +1 more source
X-Ray Photon Correlation Spectroscopy with Coherent Nanobeams: A Numerical Study
X-ray photon correlation spectroscopy accesses a wide variety of dynamic phenomena at the nanoscale by studying the temporal correlations among photons that are scattered by a material in dynamical equilibrium when it is illuminated with a coherent X-ray
Oier Bikondoa, Dina Carbone
doaj +1 more source
Capillary wave dynamics on supported viscoelastic films: Single and double layers
We study the capillary wave dynamics of a single viscoelastic supported film and of a double layer of immiscible viscoelastic supported films. Using both simple scaling arguments and a continuum hydrodynamic theory, we investigate the effects of ...
Henle, Mark L., Levine, Alex J.
core +1 more source
Impact of an Irreversibly Adsorbed Layer on Local Viscosity of Nanoconfined Polymer Melts [PDF]
We report the origin of the effect of nanoscale confinement on the local viscosity of entangled polystyrene (PS) films at temperatures far above the glass transition temperature.
Endoh, M.K. +6 more
core +2 more sources
Proposed model for the dual role of cNOS in DNA damage and repair upon UV radiation. Abstract Solar ultraviolet (sUV) radiation is a major environmental factor that induces DNA damage, promoting skin aging and carcinogenesis. The formation of cyclobutane pyrimidine dimers (CPDs) is one of the most prevalent forms of UV‐induced DNA lesions, playing a ...
Veronica Bahamondes Lorca +8 more
wiley +1 more source
Evaluation of XPC and prototypes on aflatoxin-challenged broilers
Various products and prototypes were added to poultry diets during an aflatoxin challenge on growth and histological parameters. Male broiler chicks were randomly assigned to 8 treatment groups with 8 replicates/treatment and 3 birds/replicate. Treatments were as follows: 1) negative control containing no aflatoxin (NC); 2) positive control containing ...
G D, Osweiler +6 more
openaire +2 more sources
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Neuronal degeneration is a hallmark of many DNA repair syndromes. Yet, how DNA damage causes neuronal degeneration and whether defects in different repair systems affect the brain differently is largely unknown.
Dick Jaarsma +10 more
doaj +1 more source
Glutamine deprivation triggers ACSL5 upregulation in tumor cells, sustaining their viability via dual metabolic rewiring programs. ACSL5 enhances glycolysis by relieving p53's inhibition of PGAM1 while also sustaining mitochondrial respiration and TCA cycle flux through promoting IDH2 dimerization.
Shuai Tian +11 more
wiley +1 more source
Glassy and liquid metals, from microscopic to macroscopic dynamics [PDF]
Peer ReviewedPostprint (author's final ...
Pineda Soler, Eloi, Soriano, Daniel
core

