Polymorphisms in the DNA Repair GenesXPC, XPD, andXPGand Risk of Cutaneous Melanoma: a Case-Control Analysis [PDF]
Chunying Li +13 more
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XPC promotes MDM2-mediated degradation of the p53 tumor suppressor
Although ubiquitin receptor Rad23 has been implicated in bringing ubiquitylated p53 to the proteasome, how Rad23 recognizes p53 remains unclear. We demonstrate that XPC, a Rad23-binding protein, regulates p53 turnover. p53 protein in XPC-deficient cells remains ubiquitylated, but its association with the proteasome is drastically reduced, indicating ...
Krzeszinski, Jing Yan +7 more
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Direct observation of atomic network migration in glass
Many physical properties of glasses are still far from being understood at the atomic level. The lack of experimental methods capable of studying glassy dynamics at this scale has impeded the development of a complete model for atomic transport processes.
Manuel Ross +3 more
doaj +1 more source
Epidermal transit of replication-arrested, undifferentiated keratinocytes in UV-exposed XPC mice: An alternative to in situ apoptosis [PDF]
Gerdine J. Stout +7 more
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Cullin 4A-mediated Proteolysis of DDB2 Protein at DNA Damage Sites Regulates in Vivo Lesion Recognition by XPC [PDF]
Mohamed Elmahdy +5 more
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Self-assembly and dynamic behavior of colloidal rods in the isotropic phase
In this study, we have investigated the dynamic behavior of colloidal rods within their isotropic phase, employing multispeckle ultrasmall-angle x-ray photon correlation spectroscopy (UA-XPCS) focusing on the understanding of the interplay between ...
Md. Arif Kamal, Thomas Zinn, Antara Pal
doaj +1 more source
752 Phosphorylation of XPC regulates XPC’s function in UV-induced DNA damage repair [PDF]
P. Shah, B. Zhao, L. Qiang, Y. He
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Polymer‐coated nanoparticles are widely studied in the context of nanomedicine and it is therefore of utmost importance to understand not only how their structure but also how their colloidal dynamics are affected by physiologically relevant conditions ...
Ferdinand Otto +6 more
doaj +1 more source
535 RNA interference and Chemical-Based High Content Screening for the Normlaization of XPC Phenotype [PDF]
Farah Kobaisi +5 more
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