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Verbund: Bio-XPCS; Protein-Dynamik
Das Ziel dieses Projekts war es, eine neue Einrichtung an der Strahllinie P10, PETRA III des DESY zu konstruieren und in Betrieb zu nehmen, die es ermöglicht, die Dynamik in biologischen Systemen mithilfe der Röntgenphotonen-Korrelationsspektroskopie (XPCS) zu untersuchen. Die Dynamik in konzentrierten Proteinsystemen ist von grundlegendem Interesse inopenaire +1 more source
Cancer research, 2000
We have examined the mutational spectrum in the Trp53 gene from UVB radiation-induced skin cancers in Trp53+/+ and Trp53+/- mutant mice of all three possible Xpc genotypes. Mutations were detected in exons 2-10 of the Trp53 coding region in approximately 90% of >80 different skin cancers examined. In contrast to Trp53+/+ mice in which most mutations in
A M, Reis +6 more
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We have examined the mutational spectrum in the Trp53 gene from UVB radiation-induced skin cancers in Trp53+/+ and Trp53+/- mutant mice of all three possible Xpc genotypes. Mutations were detected in exons 2-10 of the Trp53 coding region in approximately 90% of >80 different skin cancers examined. In contrast to Trp53+/+ mice in which most mutations in
A M, Reis +6 more
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X-Ray Photon Correlation Spectroscopy (XPCS)
2008G. Grübel, A. Madsen, A. Robert
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