Results 81 to 90 of about 2,411 (230)

Hepatocyte Mettl3 Deficiency Drives Primary Sclerosing Cholangitis and Liver Fibrosis via Cholangiocyte‐Macrophage Crosstalk

open access: yesAdvanced Science, Volume 13, Issue 13, 3 March 2026.
Schematic illustration demonstrating that hepatic Mettl3 depletion significantly elevates the secretion of Mif and Csf1. This elevation facilitates Trem2+ macrophage infiltration and triggers cholangiocyte remodeling through the Spp1‐Cd44 interaction, resulting in spontaneous PSC development in vivo.
Wenting Pan   +19 more
wiley   +1 more source

Towards ultrafast dynamics with split-pulse X-ray photon correlation spectroscopy at free electron laser sources

open access: yesNature Communications, 2018
X-ray photon correlation spectroscopy has been mainly used to measure slow dynamics using synchrotron sources. Here the authors demonstrate the split-and- delay pulse set-up to study nanosecond dynamics of gold nanoparticles using XPCS with free electron
W. Roseker   +15 more
doaj   +1 more source

Compressed correlation functions and fast aging dynamics in metallic glasses

open access: yes, 2013
We present x-ray photon correlation spectroscopy measurements of the atomic dynamics in a Zr67Ni33 metallic glass, well below its glass transition temperature.
B. Ruta   +4 more
core   +1 more source

Microscopic evidence of the connection between liquid-liquid transition and dynamical crossover in an ultraviscous metallic glass former [PDF]

open access: yes, 2018
Liquid-liquid transitions are interesting to many researchers since they occur in systems as diverse as monoatomic liquids, multicomponent oxides, and metallic glass formers.
Bernasconi, Andrea   +8 more
core   +5 more sources

HMGB1 Assists in Overcoming Cisplatin Resistance in Chemoresistant Human Ovarian Cancer Cells

open access: yesMolecular Carcinogenesis, Volume 65, Issue 3, Page 375-390, March 2026.
ABSTRACT Cisplatin is one of the most effective chemotherapeutic agents used in the treatment of ovarian cancer. However, the frequent development of cisplatin resistance remains a significant limitation, leading to therapeutic failure and poor patient outcomes.
Van Huynh   +3 more
wiley   +1 more source

Time-delayed beam splitting with energy separation of x-ray channels

open access: yes, 2013
We introduce a time-delayed beam splitting method based on the energy separation of x-ray photon beams. It is implemented and theoretically substantiated on an example of an x-ray optical scheme similar to that of the classical Michelson interferometer ...
Shvyd'ko, Yuri V.   +2 more
core   +1 more source

Collective pinning dynamics of charge-density waves in 1T-TaS 2 [PDF]

open access: yes, 2012
Using high-resolution x-ray scattering and x-ray photon correlation spectroscopy (XPCS), we have investigated the structure and dynamics of charge density wave (CDW) dynamics in pure and titanium-doped 1T-TaS 2.
Mohanty, Jyoti Ranjan   +4 more
core   +1 more source

Long-term XPC Silencing Reduces DNA Double-Strand Break Repair [PDF]

open access: yesCancer Research, 2007
Abstract To study the relationships between different DNA repair pathways, we established a set of clones in which one specific DNA repair gene was silenced using long-term RNA interference in HeLa cell line. We focus here on genes involved in either nucleotide excision repair (XPA and XPC) or nonhomologous end joining (NHEJ; DNA-PKcs ...
Despras, Emmanuelle   +6 more
openaire   +3 more sources

Cellular Stress, Inflammation and Barrier Damage in Gut Epithelial Cells Caused by Aspartame

open access: yesAllergy, Volume 81, Issue 3, Page 884-901, March 2026.
This study shows that aspartame, at dietary‐relevant doses, induces cytotoxicity, cellular distress associated with endoplasmic reticulum stress, oxidative stress, DNA replication and repair mechanism disturbance culminating in epithelial barrier damage.
Yagiz Pat   +16 more
wiley   +1 more source

Dynamics in shear flow studied by X-ray Photon Correlation Spectroscopy

open access: yes, 2008
X-ray photon correlation spectroscopy was used to measure the diffusive dynamics of colloidal particles in a shear flow. The results presented here show how the intensity autocorrelation functions measure both the diffusive dynamics of the particles and ...
A. Fluerasu   +19 more
core   +1 more source

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