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XRCC1 genetic polymorphism and breast cancer risk

Pharmacogenetics, 2002
Department of Industrial Hygiene and Toxicology,Finnish Institute of Occupational Health, Helsinki, FinlandCorrespondence to Daehee Kang, MD, PhD, Department of Preventive Medicine,Seoul National University College of Medicine, 28 Yongon-Dong Chongno-Gu,Seoul 110-799, KoreaTel: +82 2740 8326; fax: +82 2747 4830; e-mail dhkang@snu.ac.krReceived 30 ...
Sook-Un, Kim   +13 more
openaire   +2 more sources

Genetic polymorphisms of XRCC1 and risk of gastric cancer

Cancer Letters, 2002
Coding polymorphisms of the DNA repair gene XRCC1 have been shown to affect the DNA repair capacity and to be associated with genetic susceptibility to carcinogenesis. In our association study between three amino acid substitution polymorphisms of XRCC1 (Arg194Trp, Arg280His, and Arg399Gln) and the risk of gastric cancer in the Korean population, none ...
Seong-Gene, Lee   +5 more
openaire   +2 more sources

XRCC1 and XRCC3 variants and risk of glioma and meningioma

Journal of Neuro-Oncology, 2008
Several single nucleotide polymorphisms (SNPs) affecting DNA repair capacity and modifying cancer susceptibility have been described. We evaluated the association of SNPs Arg194Trp, Arg280His, and Arg399Gln in the X-ray cross-complementing group 1 (XRCC1) and Thr241Met in the X-ray cross-complementing group 3 (XRCC3) DNA repair genes with the risk of ...
Anne, Kiuru   +14 more
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CYP1A1 and XRCC1 gene polymorphisms in SCC of the larynx

European Journal of Cancer Prevention, 2003
The present study was undertaken to examine CYP1A1 and XRCC1 polymorphisms as potential genetic susceptibility markers for laryngeal squamous cell carcinoma (SCC). Eighty-eight patients with laryngeal SCC and 178 randomly selected healthy blood donors from the same Caucasian population (Porto, Northern Portugal) were analysed for CYP1A1 (MspI and NcoI)
G, Varzim   +4 more
openaire   +2 more sources

Expression of the DNA repair gene XRCC1 in baboon tissues

Mutation Research Letters, 1995
XRCC1 is a DNA repair gene involved in rejoining DNA strand-breaks. We used baboon as an animal model to determine the levels of XRCC1 gene expression in different tissues. Baboons were selected because they are evolutionarily closely related to humans.
Z Q, Zhou, C A, Walter
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Polymorphisms of XRCC1 and XRCC3 genes and susceptibility to breast cancer

Cancer Letters, 2003
Mammalian cells are constantly exposed to a wide variety of genotoxic agents from both endogenous and exogenous sources. Genetic variability in DNA repair may contribute to human cancer risk. We used a case-control study design (162 cases and 302 controls) to test the association between three amino acid substitution variants of DNA repair genes (XRCC1
Tasha R, Smith   +6 more
openaire   +2 more sources

Cervical cancer and XRCC1 gene polymorphisms

Revista Eletrônica Acervo Saúde
Objective: To undertake a literature review on the development of cervical cancer, emphasizing epidemiological data, human papillomavirus (HPV) infection in carcinogenesis, and the role of the XRCC1 gene in DNA repair, in order to provide valuable information for the medical and scientific community.
Andréia Michelle Alves Cunha de Alcântara   +6 more
openaire   +1 more source

[E2F1 upregulates endogenous XRCC1 expression].

Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology, 2009
To investigate the regulatory effect and significance of transcription factor E2F1 on X-ray repair cross2 complementing 1 (XRCC1).Saos2 cells were transfected with the E2F1 expression vectors (tet-E2F1) and mutated E2F1 expression vectors (tet-132E).
Juan, Li   +7 more
openaire   +1 more source

РАК ЯИЧНИКА, ИНДУЦИРОВАННЫЙ ПОЛИМОРФНЫМИ ЛОКУСАМИ RS25487/XRCC1 И RS1799782/XRCC1

Фундаментальная математика и ее приложения в естествознании, 2022
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XRCC1 prevents toxic PARP1 trapping during DNA base excision repair

Molecular Cell, 2021
Hana Hanzlíková   +2 more
exaly  

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