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Journal of Clinical Medicine, 2022 Ethnopharmacological relevance: Xuebijing injection is a Chinese herbal-derived drug composed of radix paeoniaerubra, rhizomachuanxiong, Salvia miltiorrhiza, floscarthami, and Angelica sinensis.
Youzhong An, Zhao Huiying
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Effects of Xuebijing injection on microcirculation in septic shock
Journal of Surgical Research, 2016This study was conducted to investigate whether Xuebijing injection can rectify the dysfunction of microcirculation in septic shock and assessed the microcirculatory parameters directly via orthogonal polarization spectral and software AVA 3.0.Anesthetized and mechanically ventilated beagle dogs were modeled for septic shock via lipopolysaccharide (LPS)
Liang Wang
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Phytomedicine, 2021 Xuebijing (XBJ) is a traditional Chinese patent medicine for sepsis. However, the mechanism of action (MoA) of XBJ on sepsis remain unclear.Elucidate the MoA of XBJ for treating sepsis based on network pharmacology.Integrate computational prediction, experimental validation and literature reported clinical results analysis based on network pharmacology.
Wuai Zhou, Xinxing Lai, Xiaoqing Yao
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Xuebijing in the treatment of patients with sepsis
American Journal of Emergency Medicine, 2017There are more than 18 million patients diagnosed with sepsis every year. In China, Xuebijing (XBJ) injection is a traditional medicine that is widely used in the treatment of sepsis. However, the efficacy of XBJ in treatment of randomized controlled trials (RCTs) remains unclear. This meta-analysis was to evaluate the clinical efficacy of XBJ based on
Shanwen Chen
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Xuebijing for paraquat poisoning
Cochrane Database of Systematic Reviews, 2012At present, there is a lack of effective treatments for paraquat poisoning. Xuebijing injection is a complex traditional Chinese prescription consisting of Flos Carthami, Radix Paeoniae Rubra, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae and Radix Angelicae Sinensis. Although clinical experience suggests that Xuebijing injection might have potential
Jin, Deng +4 more
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Xuebijing protects against lipopolysaccharide-induced lung injury in rabbits
Experimental Lung Research, 2010 Interleukin (IL)-23 has been identified as a member of the IL-12 cytokine family. It plays an important role in inflammation. To demonstrate the changes of IL-23 in acute lung injury (ALI) and investigate the protective effect of Xuebijing in ALI and the underlying molecular mechanism, ALI was induced by intravenous injection of lipopolysaccharide (LPS,
Junping Sun
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Impact of the gut microbiota on heat stroke rat mediated by Xuebijing metabolism
Microbial Pathogenesis, 2021The goal of the present study was to evaluate the fecal microbiome and serum metabolites in Xuebijing (XBJ)-injected rats after heat stroke using 16S rRNA gene sequencing and gas chromatography-mass spectrometry (GC-MS) metabolomics. Eighteen rats were divided into the control group (CON), heat stroke group (HS), and XBJ group.
Wen, Qiang +6 more
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Some questions on the use of Xuebijing in treating patients with sepsis
The American Journal of Emergency Medicine, 2017A meta-analysis of randomized controlled trials on evaluating the clinical efficacy of Xuebijing in treating patients with sepsis had been recently published in this journal, however, in our opinion, at least 6 questions or doubts existed about the content and methodology of the systematic review, thus, we write this letter to the journal to share ...
Xianshi, Zhou, Guanghua, Tang, Jun, Li
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Xuebijing combined with ulinastation benefits patients with sepsis: A meta-analysis
The American Journal of Emergency Medicine, 2018The potential benefits and possible risks associated with Xuebijing when combined with ulinastatin for sepsis treatment are not fully understood.Databases, such as PubMed, Web of Science, CNKI, WanFang and VIP, were searched to collect randomized, controlled trials. Studies were screened, data were extracted, and the methodological quality was assessed
Jianfei, Zheng +6 more
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Identification of the major constituents in Xuebijing injection by HPLC‐ESI‐MS
Phytochemical Analysis, 2011AbstractIntroduction – Xuebijing injection (XBJ) is a traditional Chinese herbal prescription widely used in the treatment of sepsis. This is the first report concerning the identification of XBJ constituents. In addition, to evaluate XBJ's quality, partial least square discrimination analysis (PLS‐DA) was performed on chemical fingerprint data ...
Hao, Huang +7 more
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