Superior Stability of Hydroxysafflor Yellow A in Xuebijing Injection and the Associated Mechanism [PDF]
Molecules, 2017 Hydroxysafflor yellow A (HSYA) is the main bioactive ingredient of XBJ injection. At first, the stability of HSYA in solution and in a Xuebijing injection was investigated, then the mechanisms of the increased stability of HSYA in the XBJ injection were ...
Weiling Pu +5 more
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Exploring the Mechanism of Action of Xuebijing Injection in Treating Acute Respiratory Distress Syndrome Based on Network Pharmacology and Animal Experiments [PDF]
Journal of Inflammation ResearchJin Li,1,* Meirong Shen,2,* Zuan Yin3 1Department of Intensive Care Unit, The Affiliated Hospital of Jiangxi University of Chinese Medicine, Nanchang City, Jiangxi Province, 330006, People’s Republic of China; 2Department of Intensive ...
Li J, Shen M, Yin Z
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Examining the effector mechanisms of Xuebijing injection on COVID-19 based on network pharmacology [PDF]
BioData Mining, 2020 Background Chinese medicine Xuebijing (XBJ) has proven to be effective in the treatment of mild coronavirus disease 2019 (COVID-19) cases. But the bioactive compounds and potential mechanisms of XBJ for COVID-19 prevention and treatment are unclear. This
Wen-jiang Zheng +7 more
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Detecting Critical Functional Ingredients Group and Mechanism of Xuebijing Injection in Treating Sepsis [PDF]
Frontiers in Pharmacology, 2021 Sepsis is a systemic inflammatory reaction caused by various infectious or noninfectious factors, which can lead to shock, multiple organ dysfunction syndrome, and death.
Qi- Wu +18 more
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Metabolomic Insights Into the Synergistic Effect of Biapenem in Combination With Xuebijing Injection Against Sepsis [PDF]
Frontiers in Pharmacology, 2020 The drug combination of biapenem (BIPM) and xuebijing injection (XBJ) is commonly applied for the treatment of sepsis in China. However, the potential synergistic mechanism is still enigmatic.
Li-Wei Liu +29 more
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Efficacy of Xuebijing Injection for Sepsis (EXIT-SEP): protocol for a randomised controlled trial [PDF]
BMJ Open, 2019 IntroductionSepsis is a major challenge with high incidence and is associated with high mortality worldwide. Current management of sepsis remains mainly supportive except for treatment with antibiotics. Both basic research and clinical investigation have
Junhua Zhang +3 more
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Treatment effects of Xuebijing injection in patients with sepsis by clinical phenotype: a post hoc analysis of the EXIT-SEP trialResearch in context [PDF]
EClinicalMedicineSummary: Background: Xuebijing injection (XBJ) could improve the outcomes of sepsis patients. However, sepsis is a heterogeneous syndrome, and it remains unclear which patients benefit the most.
Xiran Lou +8 more
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Integrated Transcriptomic, Proteomic, and Network Pharmacology Analyses Unravel Key Therapeutic Mechanisms of Xuebijing Injection for Severe Acute Pancreatitis [PDF]
PharmaceuticalsBackground: Xuebijing Injection (XBJ), a plant-derived traditional Chinese medicine administered as an injection, is widely used in clinical practice to treat various acute critical illnesses including severe acute pancreatitis (SAP).
Linbo Yao +17 more
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Physical compatibility of Xuebijing injection with 53 intravenous drugs during simulated Y-site administration. [PDF]
PLoS ONEObjectiveXuebijing injection (XBJ) is a commonly used herbal medicine injection in China. However, the physical compatibility of XBJ with other intravenous drugs remains unclear.
Tong Tong +4 more
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Xuebijing injection mitigates instant blood−mediated inflammatory reaction and enhances intrahepatic islet transplantation via target NF−κB pathway [PDF]
Frontiers in ImmunologyIntroductionInstant blood-mediated inflammatory reaction (IBMIR) is a major obstacle in clinical islet transplantation, leading to islet apoptosis and dysfunction due to inflammatory reaction.
Yixiang Zhan +21 more
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