Results 271 to 280 of about 157,061 (320)

Characteristics of xylazine‐related deaths in West Virginia—Xylazine‐related deaths

The American Journal on Addictions, 2022
AbstractBackground and ObjectivesThe involvement of xylazine, a veterinary drug, in West Virginia (WV) human drug‐related deaths was examined.MethodsWV drug deaths from 2019 (when xylazine was first identified) to mid‐2021. Characteristics including toxicology findings were compared between xylazine and nonxylazine deaths.ResultsOf 3292 drug deaths ...
Julie Sibbesen, Marie A. Abate, Zheng Dai, Gordon S. Smith, Eric Lundstrom, James C. Kraner, Allen R. Mock   +6 more
openaire   +2 more sources

Xylazine and Overdoses: Trends, Concerns, and Recommendations.

American Journal of Public Health, 2022
Xylazine is a nonopioid veterinary anesthetic and sedative that is increasingly detected in the illicit drug supply in the United States. Data indicate a striking prevalence of xylazine among opioid-involved overdose deaths.
R. S. Alexander, Bethany R Canver, Kimberly L Sue, K. Morford   +3 more
semanticscholar   +1 more source

Understanding sensitivity and cross-reactivity of xylazine lateral flow immunoassay test strips for drug checking applications.

Drug Testing and Analysis, 2023
The continued prevalence of xylazine in the illicit drug market has necessitated development of quick and simple methods for identification, including lateral flow immunoassays (also known as "test strips"), like those frequently used to detect fentanyl.
Edward Sisco, D. Nestadt, Madeline B. Bloom, Kristin E. Schneider, Rae A Elkasabany, Saba Rouhani, Susan G. Sherman   +6 more
semanticscholar   +1 more source

Here's What to Know About Xylazine, aka Tranq, the Animal Tranquilizer Increasingly Found in Illicit Fentanyl Samples.

Journal of the American Medical Association (JAMA), 2023
This Medical News feature discusses the increasingly common combination of xylazine, an animal tranquilizer, and illicit fentanyl.
R. Rubin
semanticscholar   +1 more source

Xylazine-Associated Wounds and Related Health Concerns Among People Who Use Drugs: Reports From Front-Line Health Workers in 7 US States

Substance use & addiction journal
Background: Xylazine, an adrenergic alpha-2 agonist increasingly present in the US drug supply, is associated with severe skin ulcers and other harms. Expert knowledge from front-line harm reduction and healthcare professionals is an essential component ...
Jennifer J. Carroll
semanticscholar   +1 more source

Prevalence of xylazine in overdose cases: An analysis of Miami‐Dade County medical examiner case data

Journal of Forensic Sciences, 2023
Xylazine sedative, muscle relaxant, and analgesic used in a veterinary setting. Although xylazine was never approved for therapeutic use in humans, it has become popular in the street drug market as a cutting or bulking agent in the fentanyl and heroin ...
Rocio B. Potoukian, J. Gonyea, Elisa N Shoff, G. Hime, Diane M. Moore   +4 more
semanticscholar   +1 more source

Evaluation of the relationship of xylazine and fentanyl blood concentrations among fentanyl-associated fatalities

Clinical toxicology
Introduction Illicit fentanyl and fentanyl-analogs have produced a devastating increase in opioid fatalities in the United States. Increasingly, xylazine has been found in the illicit fentanyl supply. The role of xylazine in fentanyl intoxication remains
Hannah L Hays, Henry A Spiller, Rebecca T DeRienz, Natalie I. Rine, Han-Tian Guo, Meagan Seidenfeld, NL Michaels, Gary A. Smith   +7 more
semanticscholar   +1 more source

Xylazine in the Unregulated Drug Market: An Integrative Review of Its Prevalence, Health Impacts, and Detection and Intervention Challenges in the United States

Policy, Politics & Nursing Practice
Xylazine, a veterinary sedative, has emerged as a concerning element in the landscape of substance use in the United States. This integrative review synthesizes evidence from a systematic examination of 14 selected studies conducted between 2008 and 2023.
E. Kyei, Grace K. Kyei, Rockson Ansong, Charles K Boakye, Ernest Asamoah   +4 more
semanticscholar   +1 more source

Exploring Xylazine Awareness, Health Impacts, and Harm Reduction Strategies: Findings From a Multimethods Study in Lowell, Massachusetts

Substance use & addiction journal
Background: Xylazine, an adulterant in local drug supplies, has been detected in approximately 30% of opioid samples submitted for testing in Massachusetts.
Shikhar Shrestha, Kevin Cyr, Grace Hajinazarian, Jaime Dillon, Takkyung Oh, Jennifer Pustz, T. Stopka   +6 more
semanticscholar   +1 more source

Wound Characteristics Among Patients Exposed to Xylazine.

JAMA dermatology
Importance The alpha-2 agonist xylazine is increasingly detected as an adulterant in illicitly manufactured fentanyl. There is concern that xylazine may be responsible for an emerging pattern of necrotizing wounds among people who use drugs, but the ...
Lydia Lutz, Rachel McFadden, Lin Xu, Ranvir Bhatia, M. H. Davis, Natasa Rohacs, Jenny Wei, Jeanmarie Perrone, M. Lowenstein, Ashish P. Thakrar   +9 more
semanticscholar   +1 more source