Results 111 to 120 of about 184,467 (306)

TSPYL5 Promotes Triple‐Negative Breast Cancer Metastasis by Antagonizing USP10‐Mediated PTEN Stabilization to Unleash a ZEB1‐Dependent EMT Program

Advanced Science, EarlyView.
The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi, Ming Yi, Shengyu Xie, Zhaokun Wang, Xinyue Zhang, Yangwei Zhang, Rui Tang, Yuan Yang, Yunqiang Liu   +8 more
wiley   +1 more source

Comparing the Efficacy of Natural Oils as Clearing Agents in Histopathology Laboratory

Journal of the Scientific Society
Introduction: Xylene is used as a clearing agent during tissue processing. It acts as an irritant to humans and poses various health hazards to those who are frequently exposed. According to the literature review, our native Indian oils have the property
R. Shivani, S. Amutha, Nadeem Jeddy, Ananthalakshmi Ramamoorthy, L. J. Sai Lakshmi, Pavithra Durairaju   +5 more
doaj   +1 more source

Carbon tetrachloride-xylene equilibria

, 1963
The liquid-liquid equilibria of the ternary systems carbon tetra-chloride-xylene-propylene glycol and carbon tetrachloride-xylene-diethylene glycol were investigated.
Ram, Michael Jay
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Adsorption and Diffusion of Xylene Isomers on Mesoporous Beta Zeolite

, 2015
A systematic and detailed analysis of adsorption and diffusion properties of xylene isomers over Beta zeolites with different mesoporosity was conducted.
Duo Xu, Ruifeng Li, Jinghong Ma, Aixia Song   +3 more
core   +1 more source

PSMA8‐Containing 20S Proteasome Regulates Spermiogenesis and Male Fertility

Advanced Science, EarlyView.
PSMA8 assembles s20S proteasome that degrades specific substrates in elongating spermatids. Degradation of s20S‐substrates activates translation of FXR1‐target mRNAs, which are essential for mitochondrial sheath formation and sperm morphogenesis.
Huiwen Cao, Qianting Zhang, Wei Xu, Anxuan Fang, Haomang Xu, Cheng Qiu, Lugeng He, Chao Yu   +7 more
wiley   +1 more source

Anti-inflammatory Effect of Marhame-mafaselOintment in Male Rats

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2015
Background and Objectives: Inflammation is a protective response against invading foreign agents and necrotic tissue, which can cause tissue damage. In this research, anti-inflammatory effect of Marhame-mafaselointment consisting of Arnebiaeuchroma L ...
Mohsen Khalili Najafabadi, Mohsen Naseri, Majid Asghari, Abbas TalebiMazrae Shahi, Parvaneh Mohseni Moghaddam, Seyed Abbas Hasheminejad, Fatemeh Emadi, Zahra Bararpour, Fariba Ansari   +8 more
doaj  

A Keratinocyte‐Mast Cell NF‐κB2/CXCL2/IL‐6 Amplification Loop Enhances Cutaneous Antifungal Defense Against C. albicans

Advanced Science, EarlyView.
ABSTRACT Mast cells (MCs), key innate immune sentinels at the host–environment interface, serve as primary responders to invading pathogens. However, their specific contribution to host defense against cutaneous Candida albicans (C. albicans) infection and their synergy with other immune and non‐immune cells remain poorly understood. Here, we show that
Yan Yuan, Manyun Mao, Jiaan Zhang, Zhimin Duan, JiaNing Wang, Yujie Chen, Sihan Chen, Chuting Liang, Xvyue Zhou, Songmei Geng, Min Li, Xu Chen, Ni Lian   +12 more
wiley   +1 more source

Biomarkers [PDF]

Xylenes are aromatic hydrocarbons used for industrial applications such as the production of petrochemicals and plastics. Acute xylene exposures can negatively impact health through neurotoxicity and irritation of respiratory and dermal tissues.

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A Simple and Mild Approach for the Synthesis of p-Xylene from Bio-Based 2,5-Dimethyfuran by Using Metal Triflates

, 2017
The production of aromatic platform chemicals from biomass-derived feedstocks is of considerable importance in biomass conversion. However, the development of effective routes with simple steps and under mild conditions is still challenging.
Lu, Xingmei, Dong, Huixian, Liu, Xiaomin, Ni, Lingli, Zhang, Suojiang, Xin, Jiayu   +5 more
core   +1 more source

Cuproptosis and Mitophagy Mediated by the THUMPD1/IGF2R‐Dependent Suppression of AKT and Activation of AMPK Signaling Suppress Lung Adenocarcinoma Progression

Advanced Science, EarlyView.
THUMPD1 drives a tumor‐suppressive signaling cascade in lung adenocarcinoma by promoting IGF2R expression. IGF2R associates with PPP2R1A to suppress AKT and activate AMPK, leading to SLC31A1 upregulation and copper accumulation. Elevated copper disrupts mitochondrial metabolism and induces excessive mitophagy, thereby restraining tumor growth and ...
Kai Wu, Bo Qin, Zhuoyu Gu, Weizheng Ding, Xiaoming Chen, Kaishang Zhang, Yujin Qiao, Shuang Yuan, Song Zhao, Xiangnan Li, Peng Zhang   +10 more
wiley   +1 more source