A preliminary investigation of gene expression and levels of FSH, IL-10, and TNF-α and histological staining in natural aging mice. [PDF]
Intan YSN +3 more
europepmc +1 more source
The Regulatory Role of Iron Transporter SLC39A13 in Liver Fibrosis
SLC39A13/ZIP13, a newly discovered intracellular iron transporter, delivers iron to the ER/Golgi to catalyze procollagen hydroxylation during collagen maturation. Here, we systematically characterize the cell type‐specific functions of ZIP13 across distinct hepatic cell populations, and identify hepatic stellate cell‐specific ZIP13 as a promising and ...
Shanshan Guo +5 more
wiley +1 more source
Description of Encephalon Morphology of Nile Tilapia Oreochromis niloticus (Linnaeus, 1758) (Perciformes: Cichlidae) From Brazil. [PDF]
Pereira ALS +5 more
europepmc +1 more source
The diagram depicts the endothelial‐protective mechanism of magnesium lithospermate B (MLB) in sepsis‐associated lung injury. MLB binds GPX4 at Gly79, disrupts its interaction with FUNDC1, prevents mitophagy‐mediated GPX4 degradation, restores mitophagic flux, reduces ROS, and limits ferroptosis.
Zhixi Li +10 more
wiley +1 more source
Morphological and histopathological description of Calyptospora sp. parasitism in Cichla monoculus Spix, 1929 (Osteichthyes, Cichlidae) from the lake region of Pracuúba-Amapá, Brazil. [PDF]
Amoras ES +6 more
europepmc +1 more source
SLC2A3 derived lactate promotes metastasis through p53 lactylation at K120 and osteoclast differentiation. Pharmacological inhibition of SLC2A3 upregulates PD‐1 expression on CD8+ T cells via lactate induced p53 lactylation, which modulates immune evasion. ABSTRACT Bone metastasis is a devastating consequence of lung cancer.
Yi Ding +10 more
wiley +1 more source
Ovarian ROS-dependent IgG accumulation precedes lipofuscin deposition and follicular decline: comparative insights from the bitch and mouse models of ovarian aging. [PDF]
Montenegro L +9 more
europepmc +1 more source
Sphingomonas paucimobilis‐Driven Epithelial–Endothelial Transition in Adenomyosis Pathogenesis
This study identifies epithelial–endothelial transition (EET) as a novel adenomyosis pathogenic mechanism driven by Sphingomonas paucimobilis colonization. Systematic inhibitor experiments validate a TNFα→NF‐κB→MMP signaling cascade essential for EET. Critically, bacterial culture supernatant fails to induce pathological changes, demonstrating viable ...
Peigen Chen +7 more
wiley +1 more source
A Novel Approach for Dermal Application of Pranoprofen-Loaded Lipid Nanoparticles for the Treatment of Post-Tattoo Inflammatory Reactions. [PDF]
De Grau-Bassal G +8 more
europepmc +1 more source

