Results 201 to 210 of about 9,122 (295)

Microglial GPR35 Ameliorates Epileptogenesis and Neuroinflammation via PDGFA Domain 2 Signaling

Advanced Science, EarlyView.
Activation of microglial G protein–coupled receptor 35 (GPR35) by L‐kynurenic acid (L‐Kyna) initiates a platelet‐derived growth factor A (PDGFA)–dependent phosphoinositide 3‐kinase–protein kinase B (PI3K–AKT) signaling cascade that dampens hippocampal neuroinflammation, thereby restraining epileptogenesis, lowering seizure susceptibility, and ...
Qi Wang, Tingting Qu, Qibing Sun, Ran Li, Junfei Dong, Yuming Du, Ziyin Xuan, Lei Wang, Hanli Li, Jianyun Sun, Fangliang Chen, Jinshuai Liu, Zifan Yang, Jianxiang Lei, Qian Yang, Bin Wang, Zhiming Zhou, Yu Wang   +17 more
wiley   +1 more source

Micromeria congesta Alleviates LPS-Induced Inflammation, Apoptosis, Oxidative Stress and DNA Damage in Rat Heart and Kidneys. [PDF]

Vet Med Sci
Dörtbudak MB, Demircioğlu M, Kapucuk FS.   +2 more
europepmc   +1 more source

Ueber die Produkte der Einwirkung von Aluminiumchlorid auf Aethylidenchlorid und Benzol, oder Toluol, oder m‐Xylol

R. Anschütz, E. Romig
semanticscholar   +1 more source

miR‐135a‐5p Is a Promising Target to Prevent the Glomerulosclerosis Associated with Podocyte Developmental Toxicity in Offspring Induced by Prenatal Dexamethasone Exposure

Advanced Science, EarlyView.
Prenatal dexamethasone exposure (PDE) programs persistent podocyte developmental injury and adult glomerulosclerosis. Mechanistically, glucocorticoid receptor (GR) binds the miR‐135a‐5p promoter and recruits the histone acetyltransferase p300, increasing promoter histone acetylation and sustaining miR‐135a‐5p expression. Elevated miR‐135a‐5p suppresses
Xiaoqi Zhao, Haiyun Chen, Yanan Zhu, Zhiping Xia, Hangyuan He, Yutang Liu, Tianshu Yang, Hui Wang, Ying Ao   +8 more
wiley   +1 more source

Humanized and Charge‐Optimized CSPG4‐Specific CAR‐T Cells show Enhanced Efficacy against Head and Neck Squamous Cell Carcinoma

Advanced Science, EarlyView.
CSPG4 is identified as a high‐value, stemness‐associated target in HPV‐negative HNSCC. By implementing rational biophysical engineering, a humanized and charge‐optimized CAR is developed to overcome tonic signaling‐induced exhaustion. This strategy induces a profound transcriptomic shift toward a rejuvenated, stem‐like memory state, significantly ...
Xiang Xu, Shizhen Qiu, Zhitong Wang, Dan Li, Min Chen, Yinying Chu, Guangfei Li, Yi Fang, Changjiang Li, Fang Shi, Peijie He, Haitao Wu, Haopeng Wang, Jian Chen   +13 more
wiley   +1 more source

Quantitative Stain Mapping in X‐Ray Virtual Histology

Advanced Science, EarlyView.
Virtual histology promises 3D tissue examination without physical sectioning, yet has lacked the tissue‐specificity of conventional pathology. This work demonstrates the first quantitative three‐dimensional stain mapping at histologically relevant resolution, separating contrast agent from tissue to reveal cellular features such as nuclei. The approach
Dominik John, David M. Paganin, Marie‐Christine Zdora, Lisa Marie Petzold, Patrick Ilg, Junan Chen, Sara Baggio, Johannes B. Thalhammer, Sami Wirtensohn, Julian Moosmann, Jörg U. Hammel, Felix Beckmann, Samantha J. Alloo, Jannis N. Ahlers, Madleen Busse, Julia Herzen, Kaye S. Morgan   +16 more
wiley   +1 more source

The Results of Intestinal Villi of Laying Hens Exposed With Avian Pathogenic <i>Escherichia coli</i> (APEC) After Giving Citric Acid and Dextrose. [PDF]

Vet Med Int
Warsito SH, Lamid M, Al-Arif MA, Hermadi HA, Sabdoningrum EK, Ayuti SR, Hsuuw YD.   +6 more
europepmc   +1 more source

Xylol verbrückte Perylenbisimid Cyclophane und Makrozyklen

, 2017
Spenst, Peter
openalex   +1 more source

Untersuchungen über die Kohlenwasserstoffe des Steinkohlentheers; von F. Beilstein. Vierte Abhandlung. Zur Kenntniss des Xylols: I. Xylylsulfhydrat (Sulfoxenol) C₈H₁₀S

H. Yssel de Schepper
openalex   +2 more sources

Untersuchungen über die Kohlenwasserstoffe des Steinkohlentheers; von F. Beilstein. Vierte Abhandlung. Zur Kenntniss des Xylols: Nitroxylol, Xylidin und Derivate. Xylidin [PDF]

G. Deumelandt
openalex   +1 more source