Results 201 to 210 of about 102,889 (306)

NELFA-mediated pausing restrains YAP transcription and context-dependent outcomes in breast cancer. [PDF]

Front Oncol
Vasave BS, Atreya AA, Kulkarni RD, Nagarkar SS, Salvi KR, Koppiker CB, Shashidhara LS, Kulkarni MD.   +7 more
europepmc   +1 more source

Loss of POGLUT2/3‐mediated O‐glucosylation produces lung and aortic phenotypes reminiscent of fibrillin1 mutants

Developmental Dynamics, EarlyView.
Abstract Background Fibrillins provide a scaffold for elastic fiber formation, which enables lung recoil and aortic compliance. Abnormal fibrillin microfibrils, as in Marfan syndrome, lead to enlarged alveoli, vascular stiffening, and aneurysms. Our earlier studies suggested that fibrillin function depends on O‐glucosylation of its epidermal growth ...
Sanjiv Neupane, Angelina Almiroudis, Kaitlyn E. Donnelly, Robert S. Haltiwanger, Bernadette C. Holdener   +4 more
wiley   +1 more source

Molecular signatures and lineage diversification of neurogenic and gliogenic radial glia in the gyrencephalic ferret cortex. [PDF]

Commun Biol
Li J, Yang F, Li W, Fu T, Li Z, Sha Z, Zheng W, Yang C, Yu J, Han D, Jiang X, You Y, Li X, Ma T, He M, Xu Z, Song X, Chen B, Ding J, Wang X, Zhang Z, Yang Z.   +21 more
europepmc   +1 more source

Skin Shade Discrimination Is Associated With Disordered Weight Control Behaviors in Hong Kong, Malaysia, Singapore, and Thailand

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Emerging evidence indicates that experiencing discrimination is associated with disordered eating. This study aimed to test the association between experiences of colorism (skin shade discrimination penalizing those with darker skin) and the prevalence of disordered weight control behaviors (DWCBs) in four Asian countries/regions ...
Nadia Craddock, S. Bryn Austin, Flora Or, Wipada Rodtanaporn, Paul White, Sook Ning Chua   +5 more
wiley   +1 more source

Hemodynamics and matrix stiffness shape the pathogenicity of SPP1⁺ macrophages. [PDF]

Front Immunol
Zhang H, Han J, Zhu S, Yi M, Fan K, Chang R, Shi Y, Dong H.   +7 more
europepmc   +1 more source

Fishing in Yap

Journal of the Anthropological Society of Nippon, 1939
openaire   +2 more sources

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Targeted Modulation of YAP Signaling: Advancing Small-Molecule Strategies in Oncology and Tissue Regeneration. [PDF]

ACS Med Chem Lett
Renner AC, Kargbo RB.
europepmc   +1 more source

Cannabidiol reduces atypical absence seizures and epileptic spasms in a Gabrb3+/D120N mouse model of Lennox–Gastaut syndrome

Epilepsia Open, EarlyView.
Abstract Objective Lennox–Gastaut syndrome (LGS) is a drug‐resistant developmental and epileptic encephalopathy (DEE). Preclinical drug development for LGS is constrained by a lack of syndrome‐relevant animal models. We aimed to evaluate a Gabrb3+/D120N knock‐in (KI) mouse model of LGS by quantifying atypical absence seizures and epileptic spasms and ...
Thomas Harman, Laura A. Sharman, Ka Lai Yip, Miguel Bedoya‐Pérez, Vaishali Janve, Jonathon C. Arnold   +5 more
wiley   +1 more source

The Regulation and Function of Hippo/YAP Pathway in Cancer. [PDF]

FASEB J
Ghosh C, Kakar R, Torkamboor S, Sun Y.
europepmc   +1 more source