Results 221 to 230 of about 283,339 (312)

Piperlongumine suppresses YAP-ET-1-CXCL2 signaling to modulates aggressiveness of triple-negative breast cancer cells. [PDF]

Transl Oncol
Hsieh MY, Yang CC, Hsu WJ, Liu ZW, Lu HY, Chiang MC, Huang CJ, Liao CY, Lin CW, Shueng PW.   +9 more
europepmc   +1 more source

Spatiotemporal cellular dynamics of the notochord shape intervertebral disc morphogenesis in the mouse embryo through apoptosis and proliferation

Developmental Dynamics, EarlyView.
Abstract Background The notochord is a midline structure essential for vertebrate embryogenesis, contributing to the development of the nervous system, digestive tract, and vertebral column. In particular, notochord signaling is indispensable for proper patterning and coordinated development of alternating vertebrae and intervertebral discs (IVDs ...
Julie Warin, Estelle Balissat, Pauline Colombier, Lily Paillat, Maeva Dutilleul, Anne Camus   +5 more
wiley   +1 more source

FAM188B promotes progression of hepatocellular carcinoma by regulating YAP/TAZ via interaction with USP10. [PDF]

J Cancer
Hu S, Wen Y, Chen Y, Fang Y, Mu M, Tu L, Chen W, Tu K, Liu X, Xu Q, Huang D, Li X.   +11 more
europepmc   +1 more source

Skin Shade Discrimination Is Associated With Disordered Weight Control Behaviors in Hong Kong, Malaysia, Singapore, and Thailand

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Emerging evidence indicates that experiencing discrimination is associated with disordered eating. This study aimed to test the association between experiences of colorism (skin shade discrimination penalizing those with darker skin) and the prevalence of disordered weight control behaviors (DWCBs) in four Asian countries/regions ...
Nadia Craddock, S. Bryn Austin, Flora Or, Wipada Rodtanaporn, Paul White, Sook Ning Chua   +5 more
wiley   +1 more source

HSPA5 promotes YAP/TAZ stability independently of the Hippo pathway and induces proneural-to-mesenchymal transition in glioblastoma. [PDF]

Cell Death Dis
Gui S, Yu W, Song Z, Peng L, Luo H, Huang K, Xiao J, Xie J, Cai S, Yuan S, Tao Z, Cheng Z.   +11 more
europepmc   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

YAP Inhibits HIV-1 transcription and promotes HIV-1 latency by regulating E3 ubiquitin ligase UHRF1 mediated tat degradation. [PDF]

PLoS Pathog
Zhou C, He H, Zhang Y, Liu X, Xia M, Qiu J, Wu Z, Rashid HK, Liu W, Peng J, Li L.   +10 more
europepmc   +1 more source

Allyship Motives and Their Differential Associations With Identity and Collective Action

European Journal of Social Psychology, EarlyView.
ABSTRACT Across three studies (N = 785) in the context of anti‐racist collective action in the United States and Germany, we empirically validate a theoretical framework of four motives for advantaged group allyship: outgroup‐focused, ingroup‐focused, personal and morality. We investigate the types of identification these motives stem from and how they
Lea Hartwich, Julia C. Becker
wiley   +1 more source

Mesenchymal stem cells differentiate dynamic from static load through variable regulation of the Hippo pathway. [PDF]

J Biomech
Xie Z, Sen B, Nikitina N, Howard S, Styner M, Rubin C, Uzer G, Rubin J.   +7 more
europepmc   +1 more source

Decoding epilepsy's molecular blueprint: Machine learning unravels transcriptomic subtypes and regulatory networks

Epilepsia, EarlyView.
Abstract Objective Drug‐resistant epilepsy (DRE) affects approximately one‐third of patients with epilepsy. The molecular heterogeneity underlying DRE remains poorly defined, largely due to limited access to resected brain tissue and substantial genetic diversity.
Yanping Weng, Yu Ma, Wanwan Hou, Haibo Li, Yuanfeng Zhou, Rui Zhao, Hao Li, Lian Chen, Yangyang Ma, Li Jin, Yi Wang, Yu An   +11 more
wiley   +1 more source