Results 221 to 230 of about 62,440 (265)

Roles of YAP/TAZ in ferroptosis

Trends in Cell Biology, 2022
Ferroptosis is a unique iron-dependent form of regulated cell death. Recently, researchers found that ferroptosis was sensitive to cell density, regulated by Hippo signaling. This article summarizes the roles of the Hippo pathway effectors Yes-associated protein (YAP) and transcriptional coactivator with PDZ-binding motif (TAZ) in ferroptosis and the ...
Suchitra Magesh, Danfeng Cai
openaire   +2 more sources

YAP tips the balance

Nature Reviews Cancer, 2010
A complex interdependent regulatory network exists between YAP, ASPP1 and LATS in the control of apoptosis.
openaire   +2 more sources

Role of YAP/TAZ in mechanotransduction

Nature, 2011
Cells perceive their microenvironment not only through soluble signals but also through physical and mechanical cues, such as extracellular matrix (ECM) stiffness or confined adhesiveness. By mechanotransduction systems, cells translate these stimuli into biochemical signals controlling multiple aspects of cell behaviour, including growth ...
DUPONT, SIRIO, MORSUT, LEONARDO, ARAGONA, MARIACELESTE, ENZO, ELENA, GIULITTI, STEFANO, CORDENONSI, MICHELANGELO, ZANCONATO, FRANCESCA, Le Digabel J, Forcato M, Bicciato S, ELVASSORE, NICOLA, PICCOLO, STEFANO   +11 more
openaire   +3 more sources

BETting on YAP–TAZ

Nature Reviews Cancer, 2018
Two papers recently published in Nature Medicine and Science Signaling highlight the various interdependent or independent ways by which YAP and TAZ can affect tumour growth.
openaire   +2 more sources

Seismic observations at the Yap Islands and the northern Yap Trench

Tectonophysics, 1997
Abstract We conducted two seismic surveys in the Yap region to investigate tectonic activity in this area. One was conducted in the northern Yap Trench for ten days using ocean bottom seismometers, the other was conducted on the Yap Islands for eight months using a small array.
Toshinori Sato, Junzo Kasahara, Hiroshi Katao, Natsumi Tomiyama, Kimihiro Mochizuki, Sadayuki Koresawa   +5 more
openaire   +1 more source

Properly dividing with YAP

Science Signaling, 2016
YAP helps to define where cells undergoing mitosis separate.
openaire   +2 more sources

Mechanical YAPping

Science Signaling, 2011
The transcriptional regulators YAP and TAZ relay mechanical cues from the environment to the nucleus.
openaire   +1 more source

The roles of YAP T425A mutation in the regulation of YAP activity.

Yi chuan = Hereditas, 2017
The Hippo signaling pathway plays a critical role in body development and tissue growth. As the core effector of the Hippo signaling pathway, Yes-associated protein (YAP) has been reported to be involved in various kinds of human cancers. However, the mechanism for the regulation of YAP activity has not been completely understood.
Yang-lu, Yang, Zhuang-zhi, Zou, Yuan, Fang, Beibei, Mao   +3 more
openaire   +1 more source

Actin on Yap

Science Signaling, 2011
Stress fibers promote nuclear accumulation of Yap, thus promoting proliferation.
openaire   +1 more source

Yap Methylated

Science Signaling, 2013
The methyltransferase Set7 promotes cytoplasmic retention of the transcriptional coactivator Yap.
openaire   +1 more source