MiR-33a Controls hMSCS Osteoblast Commitment Modulating the Yap/Taz Expression Through EGFR Signaling Regulation [PDF]
Mesenchymal stromal cells (hMSCs) display a pleiotropic function in bone regeneration. The signaling involved in osteoblast commitment is still not completely understood, and that determines the failure of current therapies being used.
Alessandro, Riccardo +9 more
core +1 more source
Harran Ovasında Karık ve Damla Sulama Sistemlerinin Ekonomik Yönden Karşılaştırılması
Bu çal ışmada, Harran Ovas ı nda çal ışmaları n ı yürüten GAP Sulama Sistemlerinin İşletme, Bak ı m ve Yönetimi Projesinin GAP İ BY pilot alan olarak bekledi ği F ı rat Sulama Birli ği demonstrasyon alanlar ı nda, tarı m ı yap ı lan domates, biber ...
Gonca Karaca, M. Fatih Selenay
doaj +1 more source
Caveolin-1 Modulates Mechanotransduction Responses to Substrate Stiffness through Actin-Dependent Control of YAP [PDF]
The transcriptional regulator YAP orchestrates many cellular functions, including tissue homeostasis, organ growth control, and tumorigenesis. Mechanical stimuli are a key input to YAP activity, but the mechanisms controlling this regulation remain ...
Català-Montoro, M. +10 more
core +1 more source
AbstractThe YAP transcription coactivator has been implicated as an oncogene and is amplified in human cancers. Previously, it has been shown that CCN2 (connective tissue growth factor, CTGF) is a target of the tumor promoting YAP and its transcription factor target TEAD.
openaire +2 more sources
Harabe Deresi Havzasında Yağış-Akış ilişkisinin AGNPS Modeliyle Değerlendirilmesi
AGNPS modeli dünyada ve özellikle Amerika Birle şik Devletlerinde havza baz ı nda yayg ı n olarak kullan ı lan modellerden birisidir. Şanl ı urfa Köy Hizmetleri Araştı rma Enstitüsü havzalar ı ndan biri olan Harabe Deresi havzas ı verilerinin esas al ı
Cüneyt Aydın, Y. Ersoy Yıldırım
doaj +1 more source
Inhibition of yes-associated protein suppresses brain metastasis of human lung adenocarcinoma in a murine model. [PDF]
Yes-associated protein (YAP) is a main mediator of the Hippo pathway and promotes cancer development and progression in human lung cancer. We sought to determine whether inhibition of YAP suppresses metastasis of human lung adenocarcinoma in a murine ...
Chan, Geraldine +13 more
core +1 more source
Sulama Şebekelerindeki Sanat Yapılarının Yeterliliğinin Belirlenmesi
Bu çal ışmada, Köy Hizmetleri Genel Müdürlüğü, Konya Il Müdürlü ğ ü sorumluluk alan ı içinden seçilen 7 sulama şebekesindeki sanat yap ı lar ı n ı n yeterlili ğ inin belirlenmesi amaçlanm ışt ı r.
Halit Apaydın, Fazl I Öztürk
doaj +1 more source
SerpinB3 and Yap Interplay Increases Myc Oncogenic Activity [PDF]
SerpinB3 has been recently described as an early marker of liver carcinogenesis, but the potential mechanistic role of this serpin in tumor development is still poorly understood.
Biasiolo, Alessandra +16 more
core +2 more sources
Sakarya Havzası Sulamalarında Sistem Performansının Değerlendirilmesi
Bu çal ışmada, sulama sistemleri aras ı nda performans ı n karşı laşt ı rmal ı analizini sa ğ layan karşı laşt ı rma göstergeleri Sakarya Havzas ı Sulama Şebekelerine uygulanm ış ve sistem performans ı değerlendirilmi ştir.
Belgin Çakmak, Mevlüt Beyrıbey
doaj +1 more source
Fibroblasts in head neck squamous cell carcinoma associated with perineural invasion have high level nuclear Yes-Associated Protein (YAP) expression [PDF]
Paul A. Reynolds, PhD, is supported by the Melville Trust for the Care and cure of Cancer.We retrospectively studied the expression of Yes-associated protein (YAP) using immunohistochemical staining in 10 cases of head and neck squamous cell carcinoma ...
Gersten, Adam +5 more
core +1 more source

