Results 41 to 50 of about 62,440 (265)
Moderate chlorophyll-a environments reduce coral bleaching during thermal stress in Yap, Micronesia
Scientific Reports, 2023 Thermal-stress events on coral reefs lead to coral bleaching, mortality, and changes in species composition. The coral reefs of Yap, in the Federated States of Micronesia, however, remained largely unaffected by major thermal-stress events until 2020 ...
Rachael Keighan +4 more
doaj +1 more source
YAP and the drug resistance highway [PDF]
Nature Genetics, 2015 Deciphering mechanisms of drug resistance is crucial to winning the battle against cancer. A new study points to an unexpected function of YAP in drug resistance and illuminates its potential role as a therapeutic target.
Alona Keren-Paz +2 more
openaire +2 more sources
Advanced Functional Materials, EarlyView.A swelling‐programmed micropatterned hydrogel guides adherent cells through a controlled transition from cell–matrix anchoring to cadherin‐mediated cell–cell compaction, enabling rapid assembly of high‐viability spheroids with defined size and morphology.
Han Gyeol Nam +8 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang +17 more
wiley +1 more source
Gelemen Tarım işletmesindeki Hayvancılık Tesislerinn Yapısal ve Fonksiyonel özellikleri
Journal of Agricultural Sciences, 1997 Bu araştı rmada, Gelemen Tar ım Işletmesinde bulunan hayvanc ı l ı k tesislerinin yap ı sal ve fonksiyonel planlama özellikleri yönünden yeterlilik durumlar ı araştı rı lmış ve sorunlar ı belirlenmeye çal ışı lmışt ı r. Çalışma, işletmedeki 7 adet kapal
M.yavuz Çelık, M.ali Tokgöz
doaj +1 more source
YAP and the Hippo pathway in cholangiocarcinoma [PDF]
Journal of Gastroenterology, 2019 Cholangiocarcinoma (CCA) has an increasing incidence and remains a difficult to treat malignancy. In a search for more effective treatment options, progress has been made in identifying molecular drivers of oncogenic signaling including IDH mutations and FGFR2 fusions.
Takaaki Sugihara +3 more
openaire +2 more sources
Advanced Healthcare Materials, EarlyView.This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz +9 more
wiley +1 more source
Ankara Koşullarında Ayçiçeğinin Su Tüketimi
Journal of Agricultural Sciences, 1998 Ankara Üniversitesi Ziraat Fakültesi Ara ş tı rma ve Uygulama Çiftli ğ inde 1994 ve 1995 y ı llar ı nda yap ı lan bu çal ışmada, ayçiçeğ inin bitki su tüketimleri Ğlçülmüş ve baz ı tahmln yöntemleri ile hesaplanan değerlerle karşı laşt ı nlmışt ı r ...
Abdullah Kadayıfçı, Osman Yıldırım
doaj +1 more source
Yap-lin28a axis targets let7-Wnt pathway to restore progenitors for initiating regeneration
eLife, 2020 The sox2 expressing (sox2+) progenitors in adult mammalian inner ear lose the capacity to regenerate while progenitors in the zebrafish lateral line are able to proliferate and regenerate damaged HCs throughout lifetime. To mimic the HC damage in mammals,
Zhian Ye +8 more
doaj +1 more source
Targeting cancer’s sweet spot: UGP2 as a therapeutic vulnerability
Molecular & Cellular Oncology, 2021 Understanding the mechanisms governing metabolic reprogramming that underlie potential vulnerabilities in cancer cells is key to developing novel therapeutic strategies. The catalytic enzyme UDP-glucose pyrophosphorylase 2 (UGP2) drives the production of
Sunghoon Kim, Andrew Wolfe, Sung Eun Kim
doaj +1 more source