Results 81 to 90 of about 102,889 (306)

Harran Ovası Koşullarında Farklı Sulama ve Sıra Aralı klarında Yağmurlama-Damla Sulama Yöntemleriyle Sulanan Soya Fasulyesinin Su Verim ilişkisinin Saptanması

Journal of Agricultural Sciences, 2001
Bu çal ışma; Yağmurlama ve damla sulama yöntemlerinin, soya fasulyesinde dört farkl ı sulama aral ığı nda 3, 6, 9 ve 12 gün ve dört farkl ı s ı ra aral ığı 50x30, 70x30, 80x40 ve 70 cm mesafesinde verim su ili şkisini belirlemek amac ı yla yap ı ...
Erkan Boydak, Sinan Gerçek, Mehmet Şımşek, Halil Kırnak   +3 more
doaj   +1 more source

The sweet side of YAP/TAZ [PDF]

Cell Cycle, 2015
The reprogramming of cancer cell metabolism toward aerobic glycolysis, i.e. the Warburg effect, is a hallmark of cancer; the rationale for selecting such energy-inefficient metabolism is the need to increase cellular biomass and sustain the high proliferation rates of cancer cells.1 Metabolic reprogramming is generally considered as a phenotypic ...
SANTINON, GIULIA, ENZO, ELENA, DUPONT, SIRIO   +2 more
openaire   +3 more sources

Gait Analysis of Pak Biawak: A Necrobot Lizard Built using the Skeleton of an Asian Water Monitor (Varanus Salvator)

Advanced Robotics Research, EarlyView.
Pak Biawak, a necrobot, embodies an unusual fusion of biology and robotics. Designed to repurpose natural structures after death, it challenges conventional boundaries between nature and engineering. Its movements are precise yet unsettling, raising questions about sustainability, ethics, and the untapped potential of biointegrated machines.
Leo Foulds, Donan Satria Yudha, Parvez Alam   +2 more
wiley   +1 more source

Durability of Soft Pneumatic Actuators: A Review and Benchmarking Protocol

Advanced Robotics Research, EarlyView.
Lack of durability is a key challenge hindering the broad scale adoption of soft pneumatic actuators (SPAs) in automation industries. This review provides a comprehensive overview of existing research on SPA durability, introduces a standardized durability benchmarking protocol to consolidate the testing of SPAs, and outlines promising directions for ...
Dickson Chiu Yu Wong, Yucheng Luo, Rob Bernardus Nicolaas Scharff   +2 more
wiley   +1 more source

MOESM1 of Curcumin derivative WZ35 inhibits tumor cell growth via ROS-YAP-JNK signaling pathway in breast cancer

, 2019
Additional file 1: Figure S1. The effects of WZ35 on cell proliferation of normal cells. Figure S2. The effects of WZ35 on cell cycle arrest, apoptosis, migration and invasion ability. Figure S3.
Wencan Wu (1805569), Linjun Yang (652707), Zheying Tao (7841966), Liqian Zhao (7841969), Zheng Zhu (487587), Ri Cui (650428), Lihua Wang (14548), Xiangjie Huang (7841972), Bin Zheng (45359), Canwei Wang (7841963), Ye He (391485), Guang Liang (206236), Tongke Chen (7841975), Hong Chen (108084), Yun Yu (169754)   +14 more
core   +1 more source

YAP/TAZ: An epitome of tumorigenesis

Cancer Letters
Mounting evidence has demonstrated that the transcriptional coactivators Yes-associated protein (YAP) and transcriptional coactivator with PDZ-binding motif (TAZ), are the main effectors of the Hippo signal transduction pathway that is involved in multiple layered events in tumorigenesis.
Soumya Mukherjee, Emily A. Warden, Jianmin Zhang   +2 more
openaire   +3 more sources

Anti‐PD‐1 Nanobody‐Armored MSLN CAR‐T Therapy for Malignant Mesothelioma: Preclinical and Clinical Studies

Advanced Science, EarlyView.
A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun, Haochen Yang, Qing Xu, Xingya Li, Jinxing Lou, Jianchun Duan, Jiachen Xu, Zhuqing Liu, Yong Xia, Zhicai Lin, Linlin Li, Dan Sun, Jiaguo Li, Tao Liu, Jun Guo, Wenfeng Xu, Weimin Zhu, Yi Liu, Boyang Sun, Jia Zhong, Lijie Rong, Qijun Qian, Chenqi Xu, Jie Wang   +23 more
wiley   +1 more source

A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase

Advanced Science, EarlyView.
Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol, Lihi Gur‐Arie, Netanel Tzarum, Tamara Wellins, Naama Katsowich, Miriam Ravins, Michal Bejerano‐Sagie, Klil Cohen, Oded Livnah, Joshua N. Adkins, Ernesto Nakayasu, Alexei Savchenko, Yeu Khai Choong, Nikhil Kumar Tulsian, Saturo Machida, Sigal Ben‐Yehuda, Yael Litvak, J. Sivaraman, Ilan Rosenshine   +18 more
wiley   +1 more source

carliercomputationallab/stochastic-model-YAP-activation: stochastic-model-YAP-activation

<p>A stochastic model for YAP activation within focal adhesion complexes</p> <p>This repository contains the required files to run the 3D particle-based stochastic simulation for YAP activation within the focal adhesion complexes.</p&
Hamidreza Jafarinia
core   +1 more source

On the relationship of YAP and FAK in hMSCs and osteosarcoma cells: Discrimination of FAK modulation by nuclear YAP depletion or YAP silencing

Cellular Signalling, 2019
The HIPPO pathway effector YAP has been shown to be regulated by FAK-signaling. However, the existence of an inverse relationship between YAP and FAK is unknown. Here we demonstrate in hMSCs and in the human osteosarcoma derived cell line Saos that Verteporfin- or RNAi-dependent YAP depletion has opposing influence on FAK.
Husari, Ayman, Steinberg, Thorsten, Dieterle, Martin P., Prucker, Oswald, Rühe, Jürgen, Jung, Britta Antonia, Tomakidi, Pascal   +6 more
openaire   +3 more sources