Results 91 to 100 of about 62,440 (265)
CALB2 is a Mechanoresistance Gene in Metastatic Prostate Cancer
Prostate cancer cell lines of differing origins were cultured over many passages while being subjected to semi‐lethal levels of fluid shear stress, representing the harsh mechanical environment these cells are subjected to in the circulation during the process of distant metastasis.
Abigail R. Fabiano +10 more
wiley +1 more source
Ankara Koşullarında Yoncanın Su Tüketimi
Köy Hizmetleri Ankara Ara ştı rma Enstitüsünde, 1995 ve 1996 y ı lları nda, yoncan ı n bitki su tüketimleri tartil; lizimetrede ölçülmü ş ve baz ı kı sa periyotlu tahmin yöntemleri ile hesaplanan de ğerlerle karşı laşt ı nlmışt ı r. Sonuçta, deneme koş
M. Fatih Selenay, Abdullah Kadayıfcı
doaj
Mechanism of Bone-metastatic LUAD Cells Promoting Angiogenesis Through HGF/YAP Signaling Pathway
Background and objective The early stages of tumor bone metastasis are closely associated with changes in the vascular niche of the bone microenvironment, and abnormal angiogenesis accelerates tumor metastasis and progression.
Yan DENG +5 more
doaj +1 more source
Long Non-Coding RNA XIST Promotes Wilms Tumor Progression Through the miR-194-5p/YAP Axis
Xingyue He,1 Xin Luo,2 Junjun Dong,1 Xing Deng,1 Feng Liu,1,2 Guanghui Wei1,2 1Department of Urology, Children’s Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key ...
He X +5 more
doaj
ZBTB11 is identified as an oncogenic transcription factor that activates FBXO28 in breast cancer. FBXO28 promotes K48‐linked ubiquitination and degradation of MST1, suppressing Hippo signaling and enhancing epithelial–mesenchymal transition and metastasis. This transcription‐to‐ubiquitination cascade defines a prognostic biomarker axis and highlights a
An Xu +10 more
wiley +1 more source
Research Advances in Targeting the YAP/TAZ Signaling Pathway to Improve Cancer Immunotherapy
Despite the groundbreaking advances in cancer immunotherapy achieved by immune checkpoint inhibitors (ICIs), their efficacy remains limited by the immunosuppressive tumor microenvironment (TME).
Pingxu ZHANG, Yiyi ZHAN
doaj +1 more source
A rigid‑flexible integrated CO depot is engineered by embedding rigid COFQDs into a flexible ECM gel network. The rigid framework enables high‑capacity CO storage and sonodynamic bacterial killing, while the flexible ECM gel controls sustained CO release, collectively eradicating multidrug‑resistant infection and promoting scarless healing.
Baohong Sun +13 more
wiley +1 more source
Cellular forces are traditionally inferred from displacement measurements, which lack rotational information and are constrained by linear model assumptions. This work replaces displacement with rotational angle for the fundamental mechanical readout.
Linjie Ma +8 more
wiley +1 more source
Rigidity‐tunable nanovesicle (P‐Pm) with mechanically induced adjuvanticity toward tumor‐associated macrophages (TAMs) was designed to engineer R848/gp100 antigen ‐loaded nanovaccine (P@Rg‐Pm), which achieved outstanding anti‐tumor outcomes in both therapeutic and preventive model of B16‐F10 melanoma.
Bangyue Luo, Liyan Qiu
wiley +1 more source
İnsanın temel değerleri değişmese de davranışları ya da satın almaya yönelik eylemleri ve tercihleri farklılaşabiliyor. Ama dikkati çeken bir durum var ki eğer bir şeyin üzerinde çok emek sarf edersen ona daha büyük kıymet veriyorsun. Akla o anda Ferhat ile Şirin Efsanesi geliyor.
openaire +1 more source

