Results 11 to 20 of about 6,783 (182)

The association of Yarrowia lipolytica with onychomycosis [PDF]

Medical Mycology Case Reports
Onychomycosis, a common fungal nail infection, is typically caused by dermatophytes or Candida species, but rare fungal pathogens can also be involved. We describe a 20-year-old woman with persistent nail shedding who was unresponsive to standard antifungal treatments.
Julia R. Major, Claire A. Warren, Paul A. Rowley   +2 more
openaire   +4 more sources

In Vivo DNA Assembly in Yarrowia lipolytica [PDF]

ACS Synthetic Biology
The oleaginous yeast Yarrowia lipolytica is an important platform organism for biotechnology applications. In this study, we established an in vivo DNA assembly system leveraging CRISPR-Cas9 for efficient genomic integration of multiple DNA fragments into the genome of Y. lipolytica.
Wei Jiang, Ioannis Georgiadis, Tommaso Fumagalli, Shengbao Wang, Christina Vasileiou, Jonathan Dahlin, Irina Borodina   +6 more
openaire   +4 more sources

Utilization, metabolic regulation and applications of hydrophobic substrates in Yarrowia lipolytica [PDF]

Synthetic and Systems Biotechnology
The efficient use of hydrophobic substrates such as n-alkanes and fatty acids as carbon and energy sources is an important native ability of Yarrowia lipolytica. This review summarizes the crucial characteristics of Y.
Fuzhou Zhu, Lin Zhang, Jianping Wen
doaj   +2 more sources

Metabolic engineering of Yarrowia lipolytica targeting bottlenecks to boost D-Pantothenic acid biosynthesis [PDF]

Bioresources and Bioprocessing
D-Pantothenic acid (DPA), also known as vitamin B5, is a water-soluble organic acid, widely applied in foods, feeds, cosmetics, and medicines. Although numerous and rapidly developing cell factories have been established for DPA biosynthesis, there has ...
Xing-Kai Li, Nuo Zhang, Hai-Peng Li, Zheng-Yu Huang, Gao-Yue Niu, Chen-Yi Sun, Jian-He Xu   +6 more
doaj   +2 more sources

Engineering ergothioneine production in Yarrowia lipolytica [PDF]

FEBS Letters, 2021
Ergothioneine is a naturally occurring antioxidant that has shown potential in ameliorating neurodegenerative and cardiovascular diseases. In this study, we investigated the potential of the Crabtree‐negative, oleaginous yeast Yarrowia lipolytica as an alternative host for ergothioneine production.
van der Hoek, Steven A., Rusnák, Matej, Jacobsen, Irene Hjorth, Martínez, José L., Kell, Douglas B., Borodina, Irina   +5 more
openaire   +3 more sources

The complete mitochondrial genome of Yarrowia lipolytica [PDF]

Comparative and Functional Genomics, 2001
AbstractWe here report the complete nucleotide sequence of the 47.9 kb mitochondrial (mt) genome from the obligate aerobic yeast Yarrowia lipolytica. It encodes, all on the same strand, seven subunits of NADH:ubiquinone oxidoreductase (ND1‐6, ND4L), apocytochrome b (COB), three subunits of cytochrome oxidase (COX1, 2, 3), three subunits of ATP ...
Kerscher, S., Durstewitz, G., Casaregola, Serge, Gaillardin, C., Brandt, U.   +4 more
openaire   +5 more sources

Engineering Yarrowia lipolytica for the biosynthesis of geraniol

Metabolic Engineering Communications, 2023
Geraniol is a monoterpene with wide applications in the food, cosmetics, and pharmaceutical industries. Microbial production has largely used model organisms lacking favorable properties for monoterpene production. In this work, we produced geraniol in metabolically engineered Yarrowia lipolytica.
Ayushi Agrawal, Zhiliang Yang, Mark Blenner   +2 more
openaire   +3 more sources

Lipase Assay in Yarrowia lipolytica [PDF]

, 2003
Lipases (triacylglycerol acyl hydrolases, EC 3. 1.1.3) are key enzymes in fat metabolism produced by microorganisms, plants, and animals that catalyze the breakdown of triacylglycerols to free fatty adds and glycerol. In Y. lipolytica severaJ genes encoding lipases have been isoiated,LlP2 coding for a secreted lipase (Pignede et al.
Morín, M., Gonzalez, Francisco J., Choupina, Altino, Burguillo, Francisco J., Dominguez, Ángel   +4 more
openaire   +2 more sources

Biosurfactant Production from the Biodegradation of n-Paraffins, Isoprenoids and Aromatic Hydrocarbons from Crude Petroleum by Yarrowia lipolytica IMUFRJ 50682

Fermentation, 2022
Yarrowia lipolytica is a unique, strictly aerobic yeast with the ability to degrade efficiently hydrophobic substrates. In the present work, we evaluated the degrading potential of Yarrowia lipolytica IMUFRJ 50682, isolated from tropical estuarine water ...
Tatiana Felix Ferreira, Fernanda Faria Martins, Caroline Alves Cayres, Priscilla F. F. Amaral, Débora de Almeida Azevedo, Maria Alice Zarur Coelho   +5 more
doaj   +1 more source

Engineering Yarrowia lipolytica to produce glycoproteins homogeneously modified with the universal Man3GlcNAc2 N-glycan core. [PDF]

PLoS ONE, 2012
Yarrowia lipolytica is a dimorphic yeast that efficiently secretes various heterologous proteins and is classified as "generally recognized as safe." Therefore, it is an attractive protein production host.
Karen De Pourcq, Petra Tiels, Annelies Van Hecke, Steven Geysens, Wouter Vervecken, Nico Callewaert   +5 more
doaj   +1 more source