Lancet, The, 2013 Yaws is an infectious disease caused by Treponema pallidum pertenue-a bacterium that closely resembles the causative agent of syphilis-and is spread by skin-to-skin contact in humid tropical regions. Yaws causes disfiguring, and sometimes painful lesions
Oriol Mitjà Villar +2 more
exaly +4 more sources
British Medical Bulletin, 2014 INTRODUCTION: Yaws, caused by Treponema pallidum ssp. pertenue, is endemic in parts of West Africa, Southeast Asia and the Pacific. The WHO has launched a campaign based on mass treatment with azithromycin, to eradicate yaws by 2020.
Asiedu, Kingsley B +4 more
core +15 more sources
Effectiveness of single-dose azithromycin to treat latent yaws: a longitudinal comparative cohort study [PDF]
The Lancet Global Health, 2017 Summary: Background: Treatment of latent yaws is a crucial component of the WHO yaws eradication strategy to prevent relapse and the resulting transmission to uninfected children.
Oriol Mitjà, DrMD +13 more
doaj +2 more sources
Prevalence study of yaws in the Democratic Republic of Congo using the lot quality assurance sampling method. [PDF]
PLoS ONE, 2009 BACKGROUND:Until the 1970s the prevalence of non-venereal trepanomatosis, including yaws, was greatly reduced after worldwide mass treatment. In 2005, cases were again reported in the Democratic Republic of the Congo.
Sibylle Gerstl +9 more
doaj +7 more sources
Survey of Treponemal Infections in Free-Ranging and Captive Macaques, 1999–2012 [PDF]
Emerging Infectious Diseases, 2017 Survey results showed treponemal infection among pet macaques in Southeast Asia, a region with a high prevalence of human yaws. This finding, along with studies showing treponemal infection in nonhuman primates in Africa, should encourage a One Health ...
Amy R. Klegarth +15 more
doaj +3 more sources
Impact of Community Mass Treatment with Azithromycin for Trachoma Elimination on the Prevalence of Yaws. [PDF]
PLoS Neglected Tropical Diseases, 2015 BackgroundCommunity mass treatment with 30 mg/kg azithromycin is central to the new WHO strategy for eradicating yaws. Both yaws and trachoma--which is earmarked for elimination by 2020 using a strategy that includes mass treatment with 20 mg/kg ...
Michael Marks +10 more
doaj +7 more sources
Comparative efficacy of low-dose versus standard-dose azithromycin for patients with yaws: a randomised non-inferiority trial in Ghana and Papua New Guinea [PDF]
The Lancet Global Health, 2018 Summary: Background: A dose of 30 mg/kg of azithromycin is recommended for treatment of yaws, a disease targeted for global eradication. Treatment with 20 mg/kg of azithromycin is recommended for the elimination of trachoma as a public health problem ...
Michael Marks, PhD +127 more
doaj +4 more sources
Failure of PCR to Detect Treponema pallidum ssp. pertenue DNA in Blood in Latent Yaws. [PDF]
PLoS Neglected Tropical Diseases, 2015 Yaws, caused by Treponema pallidum ssp. pertenue, is a neglected tropical disease closely related to venereal syphilis and is targeted for eradication by 2020. Latent yaws represents a diagnostic challenge, and current tools cannot adequately distinguish
Michael Marks +8 more
doaj +4 more sources
Mapping the distribution of yaws and Haemophilus ducreyi in the western north region of Ghana [PDF]
BMC Infectious DiseasesBackground Treponema pallidum subspecies pertenue and Haemophilus ducreyi cause skin ulcers in impoverished communities. Historical serologic records from Ghana focus on T. pallidum, omitting potential H. ducreyi cases. The objective of this study was to
Shirley Victoria Simpson +11 more
doaj +2 more sources
Integrated Mapping of Yaws and Trachoma in the Five Northern-Most Provinces of Vanuatu. [PDF]
PLoS Neglected Tropical Diseases, 2017 Yaws and trachoma are targeted for eradication and elimination as public health problems. In trachoma-endemic populations mass administration of azithromycin can simultaneously treat yaws.
Fasihah Taleo +14 more
doaj +6 more sources