Results 91 to 100 of about 384,421 (314)

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown, Giulia Carli, Prabesh Kanel, Stiven Roytman, Jaimie Barr, Nicolaas I. Bohnen, Roger L. Albin   +6 more
wiley   +1 more source

Analysis of the disease burden of vertebral fractures in China and worldwide from 1990 to 2021 and trend forecast to 2035

Journal of Health, Population and Nutrition
Methods Using the Global Burden of Disease (GBD) 2021 database, we analyzed the epidemiological trends of VFs in China from 1990 to 2021 and further explored the disease burden characteristics by age and sex.
Hongwen Gu, Kangen Han, Junchao Li, Zhihao Zhang, Le Xing, Yin Hu, Yanchun Xie, Hailong Yu   +7 more
doaj   +1 more source

Fuel poverty, older people and cold weather: An all-island analysis [PDF]

, 2011
Executive Summary This report covers a number of different aspects of fuel poverty and older people. 1. An exploration of existing government survey data from Northern Ireland and the Republic of Ireland with a particular focus on older people and ...
Barrett, E, Browne, E, Cotter, N, Goodman, PG, McAvoy, H, Monahan, E, Zeka, A   +6 more
core   +1 more source

Is late-life dependency increasing or not? A comparison of the Cognitive Function and Ageing Studies (CFAS) [PDF]

, 2017
Background: Little is known about how dependency levels have changed between generational cohorts of older people. We estimated years lived in different care states at age 65 in 1991 and 2011 and new projections of future demand for care.
Arthur, A., Baldwin, C., Barnes, L. E., Barnes, R., Brayne, C., Brayne, Carol, Comas-Herrera, A., Dening, T., Forster, G., Gao, L., Green, E., Harrison, S., Ince, P. G., Jagger, Carol, Kingston, Andrew, Matthews, Fiona E., McKeith, I. G., Parry, B., Pickett, J., Robinson, Louise, Stephan, B. C.M., Weller, R., Wharton, S., Wittenberg, Raphael, Wohland, Pia, Woods, B.   +25 more
core   +2 more sources

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2017 [PDF]

, 2019
Importance Le cancer et les autres maladies non transmissibles (MNT) sont désormais largement reconnus comme une menace pour le développement mondial. La dernière réunion de haut niveau des Nations Unies sur les maladies non transmissibles a réaffirmé cette observation et a également souligné la lenteur des progrès accomplis dans la réalisation de la ...
Christina Fitzmaurice, Degu Abate, Naghmeh Abbasi, Hedayat Abbastabar, Foad Abd-Allah, Omar Abdel-Rahman, Ahmed Abdelalim, Amir Abdoli, Ibrahim Abdollahpour, Abdishakur S. M. Abdulle, Nebiyu Dereje Abebe, Haftom Niguse Abraha, Laith J Abu-Raddad, Ahmed Abualhasan, Isaac Akinkunmi Adedeji, Shailesh Advani, Mohsen Afarideh, Mahdi Afshari, Mohammad Aghaali, Dominic Agius, Sutapa Agrawal, Ayat Ahmadi, Elham Ahmadian, Ehsan Ahmadpour, Muktar Beshir Ahmed, Mohammad Esmaeil Akbari, Tomi Akinyemiju, Ziyad Al‐Aly, Assim M AlAbdulKader, Fares Alahdab, Tahiya Alam, Genet Melak Alamene, Birhan Alemnew, Kefyalew Addis Alene, Cyrus Alinia, Vahid Alipour, Syed Mohamed Aljunid, Fatemeh Allah Bakeshei, Majid A Almadi, Amir Almasi‐Hashiani, Ubai Alsharif, Shirina Alsowaidi, Nelson Alvis‐Guzmán, Erfan Amini, Saeed Amini, Yaw Ampem Amoako, Zohreh Anbari, Nahla Hamed Anber, Cătălina Liliana Andrei, Mina Anjomshoa, Hossein Ansari, Ansariadi Ansariadi, Seth Christopher Yaw Appiah, Morteza Arab‐Zozani, Jalal Arabloo, Zohreh Arefi, Olatunde Aremu, Habtamu Abera Areri, Al Artaman, Hamid Asayesh, Ephrem Tsegay Asfaw, Alebachew Fasil Ashagre, Reza Assadi, Bahar Ataeinia, Hagos Tasew Atalay, Zerihun Ataro, Suleman Atique, Marcel Ausloos, Leticia Ávila‐Burgos, Euripide Frinel G Arthur Avokpaho, Ashish Awasthi, Nefsu Awoke, Beatriz Paulina Ayala Quintanilla, Martin Amogre Ayanore, Henok Tadesse Ayele, Ebrahim Babaee, Umar Bacha, Alaa Badawi, Mojtaba Bagherzadeh, Eleni Bagli, Senthilkumar Balakrishnan, Abbas Balouchi, Till Bärnighausen, Robert J. Battista, Masoud Behzadifar, Meysam Behzadifar, Bayu Begashaw Bekele, Yared Belete Belay, Yaschilal Muche Belayneh, Kathleen S. Berfield, Adugnaw Berhane, Eduardo Bernabé, Mircea Beuran, Nickhill Bhakta, Krittika Bhattacharyya, Belete Biadgo, Ali Bijani, Muhammad Shahdaat Bin Sayeed, Charles Birungi, Catherine Bisignano   +99 more
openaire   +4 more sources

Location‐Specific Hematoma Volume Predicts Early Neurological Deterioration in Supratentorial ICH

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Early neurological deterioration (END) adversely affects outcomes in patients with intracerebral hemorrhage (ICH). This study aimed to determine the location‐specific hematoma volumes for END in supratentorial ICH patients. Methods We retrospectively analyzed supratentorial ICH patients presenting from two prospective cohorts.
Zuoqiao Li, Guilin Meng, Zijie Wang, Xiao Hu, Jing Cheng, Chu Chen, Tiannan Yang, Jiaxin Luo, Zizhen Meng, Xueyun Liu, Qi Li   +10 more
wiley   +1 more source

Parents with learning disabilities - the lived experience - a study for equal say, Glasgow [PDF]

, 2008
In order to more clearly identify the key issues with regard to parents with learning disabilities, Equal Say commissioned the Glasgow School of Social Work to undertake a small pilot study which aimed to: identify the likely demand for advocacy services
MacIntyre, Gillian, Stewart, Ailsa, University of Strathclyde   +2 more
core   +1 more source

Why Disability Studies Scholars Must Challenge Transmisogyny and Transphobia [PDF]

, 2018
We argue the need for coalition between trans and disability studies and activism, and that Disability Studies gives us the tools for this task. Our argument rests upon six facets.
Liddiard, Kirsty, Slater, Jen
core   +1 more source

Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli, Mudasir Andrabi, Tova Cohen, Pranali G. Patel, Tapasya Katta, Chen Lin   +5 more
wiley   +1 more source